Abstract:
:An autofluorescence lifetime wide-field imaging system that can generate contrast in underlying tissue structures of normal and malignant brain tissue samples with video rate acquisition and processing time is presented. Images of the investigated tissues were acquired with high resolution (∼35 μm) using an algorithm to produce contrast based on differences in relative lifetimes. Sufficient contrast for delineation was produced without the computation of fluorescence decay times or Laguerre coefficients. The imaged tissues were sent for histological analysis that confirmed the detected imaged tissues morphological findings and correlations between relative lifetime maps and histology identified.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Papour A,Taylor Z,Sherman A,Sanchez D,Lucey G,Liau L,Stafsudd O,Yong W,Grundfest Wdoi
10.1117/1.JBO.18.6.060504subject
Has Abstractpub_date
2013-06-01 00:00:00pages
60504issue
6eissn
1083-3668issn
1560-2281pii
1697682journal_volume
18pub_type
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