Detecting inflammation in rheumatoid arthritis using Fourier transform analysis of dorsal optical transmission images from a pilot study.

abstract：:The damage mechanism for near-infrared radiation (IRR) induced cataract is unclear. Both a photochemical and a thermal mechanism were suggested. The current paper aims to elucidate a photochemical effect based on investigation of irradiance-exposure time reciprocity. Groups of 20 rats were unilaterally exposed to 96-W...

journal_title：Journal of biomedical optics

authors： Yu Z,Schulmeister K,Talebizadeh N,Kronschläger M,Söderberg P

更新日期：2015-01-01 00:00:00

abstract：:Temperature distribution is a crucial factor in determining the outcome of laser phototherapy in cancer treatment. Magnetic resonance imaging (MRI) is an ideal method for 3-D noninvasive temperature measurement. A 7.1-T MRI was used to determine laser-induced high thermal gradient temperature distribution of target ti...

journal_title：Journal of biomedical optics

authors： Chen Y,Gnyawali SC,Wu F,Liu H,Tesiram YA,Abbott A,Towner RA,Chen WR

更新日期：2008-07-01 00:00:00

abstract：:Monitoring a degranulation process in a live mast cell is a quite important issue in immunology and pharmacology. Because the size of a granule is normally much smaller than the resolution limit of an optical microscope system, there is no direct real-time live cell imaging technique for observing degranulation proces...

journal_title：Journal of biomedical optics

authors： Yang W,Lee S,Lee J,Bae Y,Kim D

更新日期：2010-07-01 00:00:00

abstract：:The formation of kidney stones is a common and highly studied disease, which causes intense pain and presents a high recidivism. In order to find the causes of this problem, the characterization of the main compounds is of great importance. In this sense, the analysis of the composition and structure of the stone can ...

journal_title：Journal of biomedical optics

authors： Blanco F,López-Mesas M,Serranti S,Bonifazi G,Havel J,Valiente M

更新日期：2012-07-01 00:00:00

abstract：:Since 1978 in vitro fertilization (IVF) procedures have resulted in the birth of over 3 million babies. Yet in 2005, IVF procedures had a live birth rate of only 34%, with 32% of these births resulting in multiple pregnancies. These multiple pregnancies were directly attributed to the transfer of multiple embryos to i...

journal_title：Journal of biomedical optics

authors： Warger WC 2nd,Newmark JA,Warner CM,DiMarzio CA

更新日期：2008-05-01 00:00:00

abstract：:The absorption coefficient mu(a), scattering coefficient mu(s), and anisotropy factor g of diluted and undiluted human blood (hematocrit 0.84 and 42.1%) are determined under flow conditions in the wavelength range 250 to 1100 nm, covering the absorption bands of hemoglobin. These values are obtained by high precision ...

journal_title：Journal of biomedical optics

authors： Friebel M,Roggan A,Müller G,Meinke M

更新日期：2006-05-01 00:00:00

abstract：:Selective photothermal interaction using dye enhancement has proven to be effective in minimizing surrounding tissue damage and delivering energy to target tissue. During laser irradiation, the process of photon absorption and thermal energy diffusion in the target tissue and its surrounding tissue are crucial. Such i...

journal_title：Journal of biomedical optics

authors： Crochet JJ,Gnyawali SC,Chen Y,Lemley EC,Wang LV,Chen WR

更新日期：2006-05-01 00:00:00

abstract：:Under ultraviolet and visible light excitation, melanin is essentially a nonfluorescent substance. This work reports our study on near-infrared (NIR) fluorescence properties of melanins, and explores potential applications of NIR fluorescence techniques for evaluating skin disorders involving melanin. The NIR fluoresc...

journal_title：Journal of biomedical optics

authors： Huang Z,Zeng H,Hamzavi I,Alajlan A,Tan E,McLean DI,Lui H

更新日期：2006-05-01 00:00:00

abstract：:In the present study, we evaluated the applicability of ex vivo photoacoustic imaging (PAI) on small animal organs. We used photoacoustic tomography (PAT) to visualize infarcted areas within murine hearts and compared these data to other imaging techniques [magnetic resonance imaging (MRI), micro-computed tomography] ...

journal_title：Journal of biomedical optics

authors： Holotta M,Grossauer H,Kremser C,Torbica P,Völkl J,Degenhart G,Esterhammer R,Nuster R,Paltauf G,Jaschke W

更新日期：2011-03-01 00:00:00

abstract：:Utilizing a laser scanning confocal microscope system, the refractive indices of articular cartilage (AC) with mechanical or biochemical degenerations were characterized to investigate whether potential correlations exist between refractive index (RI) and cartilage degeneration. The cartilage samples collected from th...

journal_title：Journal of biomedical optics

authors： Wang K,Wu J,Day R,Kirk TB,Hu X

更新日期：2016-09-01 00:00:00

abstract：:Two-photon excitation microscopy is one of the key techniques used to observe three-dimensional (3-D) structures in biological samples. We utilized a visible-wavelength laser beam for two-photon excitation in a multifocus confocal scanning system to improve the spatial resolution and image contrast in 3-D live-cell im...

journal_title：Journal of biomedical optics

authors： Oketani R,Suda H,Uegaki K,Kubo T,Matsuda T,Yamanaka M,Arai Y,Smith N,Nagai T,Fujita K

更新日期：2019-11-01 00:00:00

abstract：:We present the design and experimental results of a new MEMS-based endoscopic optical coherence tomography (OCT) probe. The uniqueness of this miniature OCT imaging probe is a two-axis MEMS mirror with through-silicon vias (TSVs) for interconnecting. The TSV interconnection enables ultracompact probe design, successfu...

journal_title：Journal of biomedical optics

authors： Liu L,Wu L,Sun J,Lin E,Xie H

更新日期：2011-02-01 00:00:00

abstract：:By using a novel temporal characterization technique, we determined that a threshold average laser power of 160 mW is required to drill through a 0.75-mm-thick cortical bone for a Nd:YVO(4) mode-locked laser oscillator with a peak intensity of 1.3 GWcm(2). The ablation mechanism is identified as average-power induced ...

journal_title：Journal of biomedical optics

authors： Lee YM,Tu RY,Chiang AC,Huang YC

更新日期：2007-11-01 00:00:00

abstract：:Nanobioconjugates have been synthesized using cadmium selenide quantum dots (QDs), europium complexes (EuCs), and biotin. In those conjugates, long-lived photoluminescence (PL) is provided by the europium complexes, which efficiently transfer energy via Förster resonance energy transfer (FRET) to the QDs in close spat...

journal_title：Journal of biomedical optics

authors： Cywinski PJ,Hammann T,Hühn D,Parak WJ,Hildebrandt N,Löhmannsröben HG

更新日期：2014-01-01 00:00:00

abstract：:Ambulatory diffuse optical tomography (aDOT) is based on near-infrared spectroscopy (NIRS) and enables three-dimensional imaging of regional hemodynamics and oxygen consumption during a person’s normal activities. Although NIRS has been previously used for muscle assessment, it has been notably limited in terms of the...

journal_title：Journal of biomedical optics

authors： Hu G,Zhang Q,Ivkovic V,Strangman GE

更新日期：2016-09-01 00:00:00

abstract：:Malaria parasites induce morphological, biochemical, and mechanical changes in red blood cells (RBCs). Mechanical variations are closely related to the deformability of individual RBCs. The deformation of various RBCs, including healthy and malaria-infected RBCs (iRBCs), can be directly observed through quantitative p...

journal_title：Journal of biomedical optics

authors： Byeon H,Ha YR,Lee SJ

更新日期：2015-11-01 00:00:00

abstract：SIGNIFICANCE:Despite the importance of the cell membrane in regulation of drug activity, the influence of drug treatments on its physical properties is still poorly understood. The combination of fluorescence lifetime imaging microscopy (FLIM) with specific viscosity-sensitive fluorescent molecular rotors allows the qu...

journal_title：Journal of biomedical optics

authors： Shimolina LE,Gulin AA,Paez-Perez M,López-Duarte I,Druzhkova IN,Lukina MM,Gubina MV,Brooks NJ,Zagaynova EV,Kuimova MK,Shirmanova MV

更新日期：2020-12-01 00:00:00

abstract：:The ability to noninvasively image embryonic vascular anatomy in mouse models is an important requirement for characterizing the development of the normal cardiovascular system and malformations in the heart and vascular supply. Photoacoustic imaging, which can provide high resolution non invasive images of the vascul...

journal_title：Journal of biomedical optics

authors： Laufer J,Norris F,Cleary J,Zhang E,Treeby B,Cox B,Johnson P,Scambler P,Lythgoe M,Beard P

更新日期：2012-06-01 00:00:00

abstract：:Diffuse reflectance spectroscopy, which has been demonstrated as a noninvasive diagnostic technique, relies on quantitative models for extracting optical property values from turbid media, such as biological tissues. We review and compare reflectance models that have been published, and we test similar models over a m...

journal_title：Journal of biomedical optics

authors： Calabro KW,Bigio IJ

更新日期：2014-01-01 00:00:00

abstract：:Computational modeling of arterial mechanics continues to progress, even to the point of allowing the study of complex regions such as the aortic arch. Nevertheless, most prior studies assign homogeneous and isotropic material properties and constant wall thickness even when implementing patient-specific luminal geome...

journal_title：Journal of biomedical optics

authors： Genovese K,Humphrey JD

更新日期：2015-04-01 00:00:00

abstract：:Using single-molecule microscopy, we present a method to quantify the number of single autofluorescent proteins when they cannot be optically resolved. This method relies on the measurement of the total intensity emitted by each aggregate until it photobleaches. This strategy overcomes the inherent problem of blinking...

journal_title：Journal of biomedical optics

authors： Cognet L,Tardin C,Négrier ML,Breillat C,Coussen F,Choquet D,Lounis B

更新日期：2008-05-01 00:00:00

abstract：:Optical spectroscopy, imaging, and therapy tissue phantoms must have the scattering and absorption properties that are characteristic of human tissues, and over the past few decades, many useful models have been created. In this work, an overview of their composition and properties is outlined, by separating matrix, s...

journal_title：Journal of biomedical optics

authors： Pogue BW,Patterson MS

更新日期：2006-07-01 00:00:00

abstract：:Water content is an important factor for skin condition. The determination of the hydration state of the skin is necessary to obtain basic knowledge about the penetration and loss of water in the skin stratum corneum. Attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy is used to measure hy...

journal_title：Journal of biomedical optics

authors： Lucassen GW,van Veen GN,Jansen JA

更新日期：1998-07-01 00:00:00

abstract：:The nEUROPt protocol is one of two new protocols developed within the European project nEUROPt to characterize the performances of time-domain systems for optical imaging of the brain. It was applied in joint measurement campaigns to compare the various instruments and to assess the impact of technical improvements. T...

journal_title：Journal of biomedical optics

authors： Wabnitz H,Jelzow A,Mazurenka M,Steinkellner O,Macdonald R,Milej D,Żołek N,Kacprzak M,Sawosz P,Maniewski R,Liebert A,Magazov S,Hebden J,Martelli F,Di Ninni P,Zaccanti G,Torricelli A,Contini D,Re R,Zucchelli L,Spine

更新日期：2014-08-01 00:00:00

abstract：:Spatially confined and precise time delivery of neuroactive molecules is an important issue in neurophysiology. In this work we developed a technique for delivering chemical stimuli to cultured neurons consisting in encapsulating the molecules of interest in liposomes. These vectors were then loaded in reservoirs cons...

journal_title：Journal of biomedical optics

authors： Pinato G,Raffaelli T,D'Este E,Tavano F,Cojoc D

更新日期：2011-09-01 00:00:00

abstract：:The infrared and Raman spectroscopy of bone and teeth tissues are reviewed. Characteristic spectra are obtained for both the mineral and protein components of these tissues. Vibrational spectroscopy is used to study the mineralization process, to define the chemical structure changes accompanying bone diseases, and to...

journal_title：Journal of biomedical optics

authors： Carden A,Morris MD

更新日期：2000-07-01 00:00:00

abstract：:An evolving area of biomedical research is related to the creation of implantable units that provide various possibilities for imaging, measurement, and the monitoring of a wide range of diseases and intrabody phototherapy. The units can be autonomic or built-in in some kind of clinically applicable implants. Because ...

journal_title：Journal of biomedical optics

authors： Sheinman V,Rudnitsky A,Toichuev R,Eshiev A,Abdullaeva S,Egemkulov T,Zalevsky Z

更新日期：2014-01-01 00:00:00

abstract：:Intraoperative applications of near-infrared (NIR) fluorescent contrast agents can be aided by instrumentation capable of merging the view of surgical field with that of NIR fluorescence. We demonstrate augmented microscopy, an intraoperative imaging technique in which bright-field (real) and electronically processed ...

journal_title：Journal of biomedical optics

authors： Watson JR,Gainer CF,Martirosyan N,Skoch J,Lemole GM Jr,Anton R,Romanowski M

更新日期：2015-10-01 00:00:00

abstract：:Using commercially available organic fluorophores, the current applications of Förster (fluorescence) resonance energy transfer (FRET) are limited to about 80 Å. However, many essential activities in cells are spatially and/or temporally dependent on the assembly/disassembly of transient complexes consisting of large-...

journal_title：Journal of biomedical optics

authors： Maliwal BP,Raut S,Fudala R,D'Auria S,Marzullo VM,Luini A,Gryczynski I,Gryczynski Z

更新日期：2012-01-01 00:00:00

abstract：:We demonstrate the utility of functional near-infrared spectroscopy (fNIRS) as a tool for physicians to study cortical plasticity in children with cerebral palsy (CP). Motor cortex activation patterns were studied in five healthy children and five children with CP (8.4+/-2.3 years old in both groups) performing a fing...

journal_title：Journal of biomedical optics

authors： Khan B,Tian F,Behbehani K,Romero MI,Delgado MR,Clegg NJ,Smith L,Reid D,Liu H,Alexandrakis G

更新日期：2010-05-01 00:00:00