Abstract:
:A method is proposed for determining the glucose concentration on the human fingertip by extracting two optical parameters, namely the optical rotation angle and the depolarization index, using a Mueller optical coherence tomography technique and a genetic algorithm. The feasibility of the proposed method is demonstrated by measuring the optical rotation angle and depolarization index of aqueous glucose solutions with low and high scattering, respectively. It is shown that for both solutions, the optical rotation angle and depolarization index vary approximately linearly with the glucose concentration. As a result, the ability of the proposed method to obtain the glucose concentration by means of just two optical parameters is confirmed. The practical applicability of the proposed technique is demonstrated by measuring the optical rotation angle and depolarization index on the human fingertip of healthy volunteers under various glucose conditions.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Chen TL,Lo YL,Liao CC,Phan QHdoi
10.1117/1.JBO.23.4.047001subject
Has Abstractpub_date
2018-04-01 00:00:00pages
1-9issue
4eissn
1083-3668issn
1560-2281pii
JBO-170780RRjournal_volume
23pub_type
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