Abstract:
:Thermal injury, as well as other forms of severe trauma, induces simultaneous hyper- and anti-inflammatory response. While data about decreased number and responsiveness of T lymphocytes are largely consistent, reports concerning granulocytes following trauma are contradictory. Contrary to the evidence on the increased accumulation of granulocytes in the lungs or liver, the results from our laboratory demonstrated reduced granulocyte influx in the wound that heals in conditions of thermal injury. We also demonstrated evidence that indicates impaired signal transduction in granulocytes following thermal injury, as well as their divergent response regarding the adhesiveness, oxidative burst and nitric oxide production at the wound site.
journal_name
Immunol Resjournal_title
Immunologic researchauthors
Draskovic-Pavlovic B,Vucevic D,Bozic B,Majstorovic I,Colic Mdoi
10.1007/s12026-012-8280-zsubject
Has Abstractpub_date
2012-04-01 00:00:00pages
133-8issue
1-2eissn
0257-277Xissn
1559-0755journal_volume
52pub_type
杂志文章,评审abstract::An early and critical event of the human immunodeficiency virus type 1 (HIV-1) life cycle is uncoating of the viral core. Uncoating involves the disassembly of HIV-1 capsid (CA). The underlying mechanisms governing uncoating are poorly defined, and the role of viral and host factors in uncoating is not well understood...
journal_title:Immunologic research
pub_type: 杂志文章
doi:10.1007/s12026-010-8164-z
更新日期:2010-12-01 00:00:00
abstract::Assembly of the class I MHC molecule is inextricably linked to the antigen presentation function of the class I molecule. Association of the class I MHC molecule with beta 2-microglobulin (beta 2m) is a prerequisite for association with the heterodimeric protein TAP, and once peptide is acquired, the class I molecule ...
journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/BF02918217
更新日期:1995-01-01 00:00:00
abstract::The initial stages of an immune response are regulated at the level of the cell-surface antigen and Fc receptors. The extracellular portions of these receptors provide immune specificity and determine the nature of the responding effector cells, whereas the intracellular portion transduces signals into the cell and de...
journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/BF02786325
更新日期:1997-02-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1385/IR:28:3:285
更新日期:2003-01-01 00:00:00
abstract::We have used MAb to L3T4 to examine the function of L3T4+ T cells in normal and autoimmune mice. Treatment of mice with MAb to L3T4 profoundly depleted L3T4+ cells from the blood, spleen, and lymph nodes, but not the thymus. In BALB/c and C57BL/6 mice, selective depletion of L3T4+ cells blocked both primary and second...
journal_title:Immunologic research
pub_type: 杂志文章
doi:10.1007/BF02917584
更新日期:1986-01-01 00:00:00
abstract::Kv1.3 and IKCa1 lymphocyte potassium channels have been implicated as important targets of selective immunomodulation. We compared the alterations in cytokine production upon selective inhibition of Kv1.3 or IKCa1 channels (by MGTX and TRAM, respectively) in healthy donors (HD), RA and AS patients. We also determined ...
journal_title:Immunologic research
pub_type: 杂志文章
doi:10.1007/s12026-015-8683-8
更新日期:2016-04-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/s12026-012-8265-y
更新日期:2012-09-01 00:00:00
abstract::Soybeans are rich in immuno-modulatory isoflavones such as genistein, daidzein, and glycitein. These isoflavones are well-known antioxidants, chemopreventive and anti-inflammatory agents. Several epidemiological studies suggest that consumption of traditional soy food containing isoflavones is associated with reduced ...
journal_title:Immunologic research
pub_type: 杂志文章,评审
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更新日期:2012-12-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章
doi:10.1007/s12026-017-8976-1
更新日期:2018-02-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章
doi:10.1007/s12026-007-0017-z
更新日期:2007-01-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章,评审
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更新日期:2011-12-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/s12026-013-8399-6
更新日期:2013-07-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章
doi:10.1007/s12026-020-09164-2
更新日期:2020-11-03 00:00:00
abstract::Immunological memory is a hallmark of adaptive immunity, a defense mechanism endowed to vertebrates during evolution. However, an autoimmune pathogenic role of memory lymphocytes is also emerging with accumulating evidence, despite reasonable skepticism on their existence in a chronic setting of autoimmune damage. It ...
journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/s12026-013-8448-1
更新日期:2013-12-01 00:00:00
abstract::Our laboratory has studied the molecular basis of T helper cell differentiation. We have used reporter transgenic mice, selective hybridization techniques, and studies of cell signaling to show that a complex pattern of gene expression is reprogrammed as the decision is made to become either a Th1 or Th2 cell. Many of...
journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/BF02786484
更新日期:1999-01-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/s12026-018-9046-z
更新日期:2019-02-01 00:00:00
abstract::Anti-CD3 monoclonal antibodies (MAbs) were developed as a way of inducing immune suppression of T cells. More recent studies have indicated that anti-CD3 MAbs can affect immune responses by inducing immune regulation. We recently reported that a single course of treatment with a non-FcR binding anti-CD3 MAb, hOKT3gamm...
journal_title:Immunologic research
pub_type: 杂志文章,评审
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更新日期:2003-01-01 00:00:00
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更新日期:2004-01-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章,评审
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更新日期:2005-01-01 00:00:00
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更新日期:2007-01-01 00:00:00
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更新日期:2005-01-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/BF02790403
更新日期:1999-01-01 00:00:00
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journal_title:Immunologic research
pub_type: 杂志文章,评审
doi:10.1007/s12026-007-8010-0
更新日期:2008-01-01 00:00:00
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更新日期:2016-04-01 00:00:00
abstract::Primary immunodeficiencies (PI) are genetic defects of the immune system that result in chronic, serious, and often life-threatening infections, if not diagnosed and treated. Many patients with PI are undiagnosed, underdiagnosed, or misdiagnosed. In fact, recent studies have shown that PI may be more common than previ...
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更新日期:2018-06-01 00:00:00
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更新日期:2008-01-01 00:00:00
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journal_title:Immunologic research
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更新日期:2014-12-01 00:00:00
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journal_title:Immunologic research
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更新日期:1989-01-01 00:00:00