Abstract：
:Drosophila melanogaster has historically been the premier model system for understanding the molecular and genetic bases of complex behaviors. In the last decade technical advances, in the form of new genetic tools and electrophysiological and optical methods, have allowed investigators to begin to dissect the neuronal circuits that generate behavior in the adult. The blossoming of circuit analysis in this organism has also reinforced our appreciation of the inadequacy of wiring diagrams for specifying complex behavior. Neuromodulation and neuronal plasticity act to reconfigure circuits on both short and long time scales. These processes act on the connectome, providing context by integrating external and internal cues that are relevant for behavioral choices. New approaches in the fly are providing insight into these basic principles of circuit function.
journal_name
Curr Opin Neurobioljournal_title
Current opinion in neurobiologyauthors
Griffith LCdoi
10.1016/j.conb.2012.01.002subject
Has Abstractpub_date
2012-08-01 00:00:00pages
609-14issue
4eissn
0959-4388issn
1873-6882pii
S0959-4388(12)00004-9journal_volume
22pub_type
杂志文章,评审abstract：:Recent studies have provided a significant advance in our understanding of motor axon pathfinding. In particular, sources of guidance cues and some of the mechanisms used by motor growth cones during pathfinding have been identified. ...
journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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更新日期：1995-12-01 00:00:00
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.conb.2020.02.001
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
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journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
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journal_title：Current opinion in neurobiology
pub_type： 杂志文章,评审
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