Abstract:
:The development of increasingly sophisticated methods for recording and manipulating neural activity is revolutionizing neuroscience. By probing how activity patterns in different types of neurons and circuits contribute to behavior, these tools can help inform mechanistic models of brain function and explain the roles of distinct circuit elements. However, in systems where functions are distributed over large networks, interpreting causality experiments can be challenging. Here we review common assumptions underlying circuit manipulations in behaving animals and discuss the strengths and limitations of different approaches.
journal_name
Curr Opin Neurobioljournal_title
Current opinion in neurobiologyauthors
Wolff SB,Ölveczky BPdoi
10.1016/j.conb.2018.01.004subject
Has Abstractpub_date
2018-04-01 00:00:00pages
84-94eissn
0959-4388issn
1873-6882pii
S0959-4388(17)30224-6journal_volume
49pub_type
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