The neural circuits of thermal perception.

Abstract:

:Thermal information about skin surface temperature is a key sense for the perception of object identity and valence. The identification of ion channels involved in the transduction of thermal changes has provided a genetic access point to the thermal system. However, from sensory specific 'labeled-lines' to multimodal interactive pathways, the functional organization and identity of the neural circuits mediating innocuous thermal perception have been debated for over 100 years. Here we highlight points in the system that require further attention and review recent advances using in vivo electrophysiology, cellular resolution calcium imaging, optogenetics and thermal perceptual tasks in behaving mice that have begun to uncover the anatomical principles and neural processing mechanisms underlying innocuous thermal perception.

journal_name

Curr Opin Neurobiol

authors

Bokiniec P,Zampieri N,Lewin GR,Poulet JF

doi

10.1016/j.conb.2018.04.006

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

98-106

eissn

0959-4388

issn

1873-6882

pii

S0959-4388(18)30006-0

journal_volume

52

pub_type

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