Glial regulation of the axonal membrane at nodes of Ranvier.

abstract：:How is an ant-equipped with a brain that barely exceeds the size of a pinhead-capable of achieving navigational marvels? Even though evidences suggest that navigation is a multimodal process, ants heavily depend on olfactory cues-of pheromonal and non-pheromonal nature-for foraging and orientation. Recent studies have...

journal_title：Current opinion in neurobiology

authors： Steck K

更新日期：2012-04-01 00:00:00

abstract：:The heated debate over the level of postsynaptic receptor occupancy by transmitter has not been extinguished - indeed, new evidence is fanning the flames. Recent experiments using two-photon microscopy suggest that the concentration of glutamate in the synaptic cleft does not attain levels previously suggested. In con...

journal_title：Current opinion in neurobiology

authors： Bergles DE,Diamond JS,Jahr CE

更新日期：1999-06-01 00:00:00

abstract：:In the mammalian cortex, the classic view assumes that the output information of a neuron is encoded in rather stereotyped action potentials, which provide an all-or-none or digital way of communication between cell body and axonal boutons. A role for subthreshold signal propagation within cortical axons has largely b...

journal_title：Current opinion in neurobiology

authors： Alle H,Geiger JR

更新日期：2008-06-01 00:00:00

abstract：:Recent findings suggest that cerebral laterality will not be understood in terms of simple dichotomies, such as the idea that the left hemisphere is analytic and the right holistic. Rather, hemisphere differences can be better explained in terms of relatively specific principles that extend over limited domains. For v...

journal_title：Current opinion in neurobiology

authors： Brown HD,Kosslyn SM

更新日期：1993-04-01 00:00:00

abstract：:The circuitry mediating the integration of reward perception and adaptive behavioral responses has been further refined. Recent developments indicate that the nucleus accumbens has a primary role in motivational circuitry, whereas afferents to the nucleus accumbens, in part, subserve distinct functions. Dopaminergic a...

journal_title：Current opinion in neurobiology

authors： Kalivas PW,Nakamura M

更新日期：1999-04-01 00:00:00

abstract：:It is now 15 years since the discovery that N-methyl-d-aspartate receptor activity is required to maintain the refined topographic organization of retinotectal projections. Recent studies have identified additional components of the signaling pathways required for activity-dependent map formation and maintenance. Nitr...

journal_title：Current opinion in neurobiology

authors： Debski EA,Cline HT

更新日期：2002-02-01 00:00:00

abstract：:Studies of the function of the basal forebrain have focused on cholinergic neurons that project to cortical and limbic structures critical for various cognitive abilities. Recent experiments suggest that these neurons serve a modulatory function in cognition, by optimizing cortical information processing and influenci...

journal_title：Current opinion in neurobiology

authors： Baxter MG,Chiba AA

更新日期：1999-04-01 00:00:00

abstract：:A recent series of exciting observations, using novel high-resolution time-lapse imaging of living cells, has provoked a major shift in our understanding of the dendritic spine, from a stable storage site of long-term memory to a dynamic structure that undergoes rapid morphological variations. Through these recent obs...

journal_title：Current opinion in neurobiology

authors： Segal M,Andersen P

更新日期：2000-10-01 00:00:00

abstract：:Previously, eye positions were characterized by the direction of sight, which has two degrees of freedom for conjugate movements and three degrees of freedom for vergent movements. Several groups have recently presented reliable data and unconventional models on binocular coordination, where all three degrees of freed...

journal_title：Current opinion in neurobiology

authors： Hepp K

更新日期：1994-12-01 00:00:00

abstract：:Neuropeptide Y is an important regulator of energy intake and expenditure. The central portion of this regulatory system appears to reside in the arcuate nucleus/paraventricular nucleus of the hypothalamus. The effects of neuropeptide Y on energy metabolism include increased food intake, decreased thermogenesis and in...

journal_title：Current opinion in neurobiology

authors： Billington CJ,Levine AS

更新日期：1992-12-01 00:00:00

abstract：:Parenting is essential for survival and wellbeing in many species. Since it can be performed with little prior experience and entails considerable sacrifices without immediate benefits for the caregiver, this behavior is likely orchestrated by evolutionarily shaped, hard-wired neural circuits. At the same time, experi...

journal_title：Current opinion in neurobiology

authors： Kohl J

更新日期：2020-02-01 00:00:00

abstract：:Recent data show that the ventral premotor cortex in both humans and monkeys has motor and cognitive functions. The cognitive functions include space perception, action understanding and imitation. The data also show a clear functional homology between monkey area F5 and human area 44. Preliminary evidence suggests th...

journal_title：Current opinion in neurobiology

authors： Rizzolatti G,Fogassi L,Gallese V

更新日期：2002-04-01 00:00:00

abstract：:A recent approach in social neuroscience has been the application of formal computational models for a particular social-cognitive process to neuroimaging data. Here we review preliminary findings from this nascent subfield, focusing on observational learning and strategic interactions. We present evidence consistent ...

journal_title：Current opinion in neurobiology

authors： Dunne S,O'Doherty JP

更新日期：2013-06-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) and positron emission tomography measure local changes in brain hemodynamics induced by cognitive or perceptual tasks. These measures have a uniformly high spatial resolution of millimeters or less, but poor temporal resolution (about 1s). Conversely, electroencephalography...

journal_title：Current opinion in neurobiology

authors： Dale AM,Halgren E

更新日期：2001-04-01 00:00:00

abstract：:Converging evidence indicates that primates have a distinct cortical image of homeostatic afferent activity that reflects all aspects of the physiological condition of all tissues of the body. This interoceptive system, associated with autonomic motor control, is distinct from the exteroceptive system (cutaneous mecha...

journal_title：Current opinion in neurobiology

authors： Craig AD

更新日期：2003-08-01 00:00:00

abstract：:mRNA localization and regulated translation take central roles in axon guidance and synaptic plasticity. By spatially restricting gene expression within neurons, local protein synthesis provides growth cones and synapses with the capacity to autonomously regulate their structure and function. Studies in a variety of s...

journal_title：Current opinion in neurobiology

authors： Martin KC

更新日期：2004-06-01 00:00:00

abstract：:We discuss very recent experiments with rodents addressing the idea that long-term memories initially depending on the hippocampus, over a prolonged period, become independent of it. No unambiguous recent evidence exists to substantiate that this occurs. Most experiments find that recent and remote memories are equall...

journal_title：Current opinion in neurobiology

authors： Sutherland RJ,Lehmann H

更新日期：2011-06-01 00:00:00

abstract：:Genetically encoded sensors of neural activity enable visualization of circuit-level function in the central nervous system. Although our understanding of the molecular events that regulate neuronal firing, synaptic function, and plasticity has expanded rapidly over the past 15 years, an appreciation for how cellular ...

journal_title：Current opinion in neurobiology

authors： Barth AL

更新日期：2007-10-01 00:00:00

abstract：:Rhythms are a prominent signature of brain activity. Their expression is correlated with numerous examples of healthy information processing and their fluctuations are a marker of disease states. Yet, their causal or epiphenomenal role in brain function is still highly debated. We review recent studies showing brain r...

journal_title：Current opinion in neurobiology

authors： Jones SR

更新日期：2016-10-01 00:00:00

abstract：:Developing axons appear to navigate to their targets partly in response to long-range diffusible chemoattractants secreted by target cells. The past year has seen the identification of the first target-derived attractants for developing axons, the netrins. Target-derived diffusible factors have also been implicated in...

journal_title：Current opinion in neurobiology

authors： Kennedy TE,Tessier-Lavigne M

更新日期：1995-02-01 00:00:00

abstract：:Animals respond to sensory cues emitted by their conspecifics by initiating a repertoire of sex-specific social behaviors, such as mating, fighting, and parental care. These behavioral responses are thought to be largely driven by genetically pre-programmed circuits. However, they can also vary significantly according...

journal_title：Current opinion in neurobiology

authors： Li Y,Dulac C

更新日期：2018-12-01 00:00:00

abstract：:How does auditory cortex represent auditory stimuli, and how do these representations contribute to behavior? Recent experimental evidence suggests that activity in auditory cortex consists of sparse and highly synchronized volleys of activity, observed both in anesthetized and awake animals. Many neurons are capable ...

journal_title：Current opinion in neurobiology

authors： Hromádka T,Zador AM

更新日期：2009-08-01 00:00:00

abstract：:Processing of auditory information requires constant adjustment due to alterations of the environment and changing conditions in the nervous system with age, health, and experience. Consequently, patterns of activity in cortical networks have complex dynamics over a wide range of timescales, from milliseconds to days ...

journal_title：Current opinion in neurobiology

authors： Froemke RC,Schreiner CE

更新日期：2015-12-01 00:00:00

abstract：:PTEN germline mutations are found in a small subset of children diagnosed with autism spectrum disorder (ASD) and accompanying macrocephaly. In this review, we discuss recent advances that offer insight into the pathogenesis of this subgroup of autism patients. We provide an overview of how disrupting PTEN function in...

journal_title：Current opinion in neurobiology

authors： Zhou J,Parada LF

更新日期：2012-10-01 00:00:00

abstract：:GABAergic interneurons in the hippocampus coordinate neuronal activity that gives rise to network oscillations. In this article we present advances in our understanding of how different classes of hippocampal interneurons contribute to distinct hippocampal network oscillations. We focus on two main experimental approa...

journal_title：Current opinion in neurobiology

authors： Allen K,Monyer H

更新日期：2015-04-01 00:00:00

abstract：:Vision research has traditionally been studied in stationary subjects observing stimuli, and rarely during navigation. Recent research using virtual reality environments for mice has revealed that responses even in the primary visual cortex are modulated by spatial context - identical scenes presented in different pos...

journal_title：Current opinion in neurobiology

authors： Saleem AB

更新日期：2020-10-01 00:00:00

abstract：:Recent developments have led to a greater insight into the complex processes of perception of visual motion. A better understanding of the neuronal circuitry involved and advances in electrophysiological techniques have allowed researchers to alter the perception of an animal with a stimulating electrode. In addition,...

journal_title：Current opinion in neurobiology

authors： Snowden RJ

更新日期：1992-04-01 00:00:00

abstract：:The glial regulation of synaptic function provides important modulation of the synaptic and behavioral changes induced by drugs of abuse. In some cases, this regulation is adaptive, reducing drug-induced change, and in other cases maladaptive, contributing to the induction or maintenance of these changes. Understandin...

journal_title：Current opinion in neurobiology

authors： Stellwagen D,Kemp GM,Valade S,Chambon J

更新日期：2019-08-01 00:00:00

abstract：:Inhibitory molecules in CNS myelin affect axonal regeneration after injury. In the past year, myelin-associated glycoprotein (MAG), a well-characterized myelin protein, has been identified as an inhibitor of axonal regeneration. This finding, together with its established ability to promote outgrowth, defines MAG as a...

journal_title：Current opinion in neurobiology

authors： Filbin MT

更新日期：1995-10-01 00:00:00

abstract：:Neuroscience research has become increasingly reliant upon quantitative and computational data analysis and modeling techniques. However, the vast majority of neuroscientists are still trained within the traditional biology curriculum, in which computational and quantitative approaches beyond elementary statistics may...

journal_title：Current opinion in neurobiology

authors： Goldman MS,Fee MS

更新日期：2017-10-01 00:00:00