Abstract:
:Laser welding has the potential to become an effective method for wound closure and healing without sutures. Closure of skin incisions by laser welding with a combination of two near-infrared lasers (980 and 1064 nm), was performed for the first time in this study. One centimeter long, full-thickness incisions were made on the Wistar rat's dorsal skin. The efficiencies of laser-welding with different parameters were investigated. Incision-healing, histology examination, and a tensile strength test of incisions were recorded. Laser welding with the irradiance level of 15.9 W∕cm(2) for both 980 and 1064-nm lasers and exposure time of 5 s per spot in continuous wave mode yielded a more effective closure and healing with minimal thermal damage, faster recovery, and stronger apposition in comparison with a suturing technique. The conclusion is that skin welding with a combination of two near-infrared diode lasers can be a good candidate for incision closure, and further investigations are in progress for clinical use.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Hu L,Lu Z,Wang B,Cao J,Ma X,Tian Z,Gao Z,Qin L,Wu X,Liu Y,Wang Ldoi
10.1117/1.3552648subject
Has Abstractpub_date
2011-03-01 00:00:00pages
038001issue
3eissn
1083-3668issn
1560-2281journal_volume
16pub_type
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