Abstract:
:Renal ischemia that occurs intraoperatively during procedures requiring clamping of the renal artery (such as renal procurement for transplantation and partial nephrectomy for renal cancer) is known to have a significant impact on the viability of that kidney. To better understand the dynamics of intraoperative renal ischemia and recovery of renal oxygenation during reperfusion, a visible reflectance imaging system (VRIS) was developed to measure renal oxygenation during renal artery clamping in both cooled and warm porcine kidneys. For all kidneys, normothermic and hypothermic, visible reflectance imaging demonstrated a spatially distinct decrease in the relative oxy-hemoglobin concentration (%HbO₂) of the superior pole of the kidney compared to the middle or inferior pole. Mean relative oxy-hemoglobin concentrations decrease more significantly during ischemia for normothermic kidneys compared to hypothermic kidneys. VRIS may be broadly applicable to provide an indicator of organ ischemia during open and laparoscopic procedures.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Crane NJ,Huffman SW,Alemozaffar M,Gage FA,Levin IW,Elster EAdoi
10.1117/1.JBO.18.3.035001subject
Has Abstractpub_date
2013-03-01 00:00:00pages
035001issue
3eissn
1083-3668issn
1560-2281pii
1658061journal_volume
18pub_type
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