当前位置： SCI文献检索 > JOURNAL OF BIOMEDICAL OPTICS期刊下所有文献 > High temperature heat source generation with quasi-continuous wave semiconductor lasers at power levels of 6 W for medical use.

High temperature heat source generation with quasi-continuous wave semiconductor lasers at power levels of 6 W for medical use.

Abstract：

:We investigate a technology to create a high temperature heat source on the tip surface of the glass fiber proposed for medical surgery applications. Using 4 to 6 W power level semiconductor lasers at a wavelength of 980 nm, a laser coupled fiber tip was preprocessed to contain a certain amount of titanium oxide powder with a depth of 100 μm from the tip surface so that the irradiated low laser energy could be perfectly absorbed to be transferred to thermal energy. Thus, the laser treatment can be performed without suffering from any optical characteristic of the material. A semiconductor laser was operated quasi-continuous wave mode pulse time duration of 180 ms and >95% of the laser energy was converted to thermal energy in the fiber tip. Based on two-color thermometry, by using a gated optical multichannel analyzer with a 0.25 m spectrometer in visible wavelength region, the temperature of the fiber tip was analyzed. The temperature of the heat source was measured to be in excess 3100 K.

journal_name

J Biomed Opt

journal_title

Journal of biomedical optics

authors

Fujimoto T,Imai Y,Tei K,Ito S,Kanazawa H,Yamaguchi S

doi

10.1117/1.JBO.19.10.101502

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

101502

issue

10

eissn

1083-3668

issn

1560-2281

pii

1875698

journal_volume

19

pub_type

杂志文章

相关文献

JOURNAL OF BIOMEDICAL OPTICS文献大全
  • Optical fiber-based dispersion for spectral discrimination in fluorescence lifetime imaging systems.

    abstract：:The excited state lifetime of a fluorophore together with its fluorescence emission spectrum provide information that can yield valuable insights into the nature of a fluorophore and its microenvironment. However, it is difficult to obtain both channels of information in a conventional scheme as detectors are typicall...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.25.1.014506

    authors： Sagar MAK,Dai B,Chacko J,Weber J,Velten A,Sanders S,White J,Eliceiri K

    更新日期：2019-12-01 00:00:00

  • In-vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography.

    abstract：:We interrogate the ability of free-space fluorescence tomography to image small animals in vivo using charge-coupled device (CCD) camera measurements over 360-deg noncontact projections. We demonstrate the performance of normalized dual-wavelength measurements that are essential for in-vivo use, as they account for th...

    journal_title：Journal of biomedical optics

    pub_type： 信件

    doi：10.1117/1.3149854

    authors： Deliolanis NC,Dunham J,Wurdinger T,Figueiredo JL,Tannous BA,Ntziachristos V

    更新日期：2009-05-01 00:00:00

  • Extending Förster resonance energy transfer measurements beyond 100 Å using common organic fluorophores: enhanced transfer in the presence of multiple acceptors.

    abstract：:Using commercially available organic fluorophores, the current applications of Förster (fluorescence) resonance energy transfer (FRET) are limited to about 80 Å. However, many essential activities in cells are spatially and/or temporally dependent on the assembly/disassembly of transient complexes consisting of large-...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.17.1.011006

    authors： Maliwal BP,Raut S,Fudala R,D'Auria S,Marzullo VM,Luini A,Gryczynski I,Gryczynski Z

    更新日期：2012-01-01 00:00:00

  • Diagnostic performance of receptor-specific surgical specimen staining correlates with receptor expression level.

    abstract：:Intraoperative margin assessment is imperative to cancer cure but is a continued challenge to successful surgery. Breast conserving surgery is a relevant example, where a cosmetically improved outcome is gained over mastectomy, but re-excision is required in >25  %   of cases due to positive or closely involved margin...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.24.2.026002

    authors： Schaefer JM,Barth CW,Davis SC,Gibbs SL

    更新日期：2019-02-01 00:00:00

  • Implantable photonic devices for improved medical treatments.

    abstract：:An evolving area of biomedical research is related to the creation of implantable units that provide various possibilities for imaging, measurement, and the monitoring of a wide range of diseases and intrabody phototherapy. The units can be autonomic or built-in in some kind of clinically applicable implants. Because ...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.19.10.108001

    authors： Sheinman V,Rudnitsky A,Toichuev R,Eshiev A,Abdullaeva S,Egemkulov T,Zalevsky Z

    更新日期：2014-01-01 00:00:00

  • Measurement of the refractive index of whole blood and its components for a continuous spectral region.

    abstract：:The refractive index of blood is a key biophysical parameter, which can reflect the physiological state. We measured the refractive index of whole blood and other components, such as serum, plasma, and hemoglobin, based on internal reflection by using a homemade apparatus in the spectral range of 400 to 750 nm. In add...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.24.3.035003

    authors： Liu S,Deng Z,Li J,Wang J,Huang N,Cui R,Zhang Q,Mei J,Zhou W,Zhang C,Ye Q,Tian J

    更新日期：2019-03-01 00:00:00

  • Quantitative polarized Raman spectroscopy in highly turbid bone tissue.

    abstract：:Polarized Raman spectroscopy allows measurement of molecular orientation and composition and is widely used in the study of polymer systems. Here, we extend the technique to the extraction of quantitative orientation information from bone tissue, which is optically thick and highly turbid. We discuss multiple scatteri...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.3426310

    authors： Raghavan M,Sahar ND,Wilson RH,Mycek MA,Pleshko N,Kohn DH,Morris MD

    更新日期：2010-05-01 00:00:00

  • Detection of breast surgical margins with optical coherence tomography imaging: a concept evaluation study.

    abstract：:This study aimed to evaluate the concept of using high-resolution optical coherence tomography (OCT) imaging to rapidly assess surgical specimens and determine if cancer positive margins were left behind in the surgical bed. A mouse model of breast cancer was used in this study. Surgical specimens from 30 animals were...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.19.5.056001

    authors： Savastru D,Chang EW,Miclos S,Pitman MB,Patel A,Iftimia N

    更新日期：2014-05-01 00:00:00

  • Analysis of blood coagulation process based on fractality and dynamic characteristic of laser speckle pattern.

    abstract：:The reflection and transmission of coherent light from a biological system can yield information about its condition. In the case of blood exposed to the air, there is a change in the properties of the speckle patterns observed in the coagulation process. This can be studied by means of the rate of temporal variation,...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.24.3.031018

    authors： Yokoi N,Aizu Y,Uozumi J

    更新日期：2018-12-01 00:00:00

  • Early diagnosis of teeth erosion using polarized laser speckle imaging.

    abstract：:Dental erosion starts with a chemical attack on dental tissue causing tooth demineralization, altering the tooth structure and making it more sensitive to mechanical erosion. Medical diagnosis of dental erosion is commonly achieved through a visual inspection by the dentist during dental checkups and is therefore high...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.21.7.071103

    authors： Abou Nader C,Pellen F,Loutfi H,Mansour R,Le Jeune B,Le Brun G,Abboud M

    更新日期：2016-07-01 00:00:00

  • Label-free optical activation of astrocyte in vivo.

    abstract：:As the most abundant cell type in the central nervous system, astrocyte has been one of main research topics in neuroscience. Although various tools have been developed, at present, there is no tool that allows noninvasive activation of astrocyte in vivo without genetic or pharmacological perturbation. Here we report ...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.3600774

    authors： Choi M,Yoon J,Ku T,Choi K,Choi C

    更新日期：2011-07-01 00:00:00

  • Development of a digital fluorescence sensing technique to monitor the response of macrophages to external hypoxia.

    abstract：:Oxygen plays a very important role in living cells. The intracellular level of oxygen is under tight control, as even a small deviation from normal oxygen level affects major cellular metabolic processes and is likely to result in cellular damage or cell death. This paper describes the use of the oxygen sensitive fluo...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.1344190

    authors： Asiedu JK,Ji J,Nguyen M,Rosenzweig N,Rosenzweig Z

    更新日期：2001-04-01 00:00:00

  • Digital phantoms generated by spectral and spatial light modulators.

    abstract：:A hyperspectral image projector (HIP) based on liquid crystal on silicon spatial light modulators is explained and demonstrated to generate data cubes. The HIP-constructed data cubes are three-dimensional images of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxyhemoglobi...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章,收录出版

    doi：10.1117/1.JBO.20.11.111215

    authors： Chon B,Tokumasu F,Lee JY,Allen DW,Rice JP,Hwang J

    更新日期：2015-01-01 00:00:00

  • Pulsed photoacoustic flow imaging with a handheld system.

    abstract：:Flow imaging is an important technique in a range of disease areas, but estimating low flow speeds, especially near the walls of blood vessels, remains challenging. Pulsed photoacoustic flow imaging can be an alternative since there is little signal contamination from background tissue with photoacoustic imaging. We p...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.21.2.026004

    authors： van den Berg PJ,Daoudi K,Steenbergen W

    更新日期：2016-02-01 00:00:00

  • Tutorial on diffuse light transport.

    abstract：:A tutorial introduction to diffuse light transport is presented. The basic analytic equations of time-resolved, steady-state and modulated light transport are introduced. The perturbation method for handling slight heterogeneities in optical properties is outlined. The treatment of boundary conditions such as an air/t...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.2967535

    authors： Jacques SL,Pogue BW

    更新日期：2008-07-01 00:00:00

  • Clinical study of noninvasive in vivo melanoma and nonmelanoma skin cancers using multimodal spectral diagnosis.

    abstract：:The goal of this study was to determine the diagnostic capability of a multimodal spectral diagnosis (SD) for in vivo noninvasive disease diagnosis of melanoma and nonmelanoma skin cancers. We acquired reflectance, fluorescence, and Raman spectra from 137 lesions in 76 patients using custom-built optical fiber-based c...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.19.11.117003

    authors： Lim L,Nichols B,Migden MR,Rajaram N,Reichenberg JS,Markey MK,Ross MI,Tunnell JW

    更新日期：2014-01-01 00:00:00

  • Temperature distribution in selective laser-tissue interaction.

    abstract：:Selective photothermal interaction using dye enhancement has proven to be effective in minimizing surrounding tissue damage and delivering energy to target tissue. During laser irradiation, the process of photon absorption and thermal energy diffusion in the target tissue and its surrounding tissue are crucial. Such i...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.2204615

    authors： Crochet JJ,Gnyawali SC,Chen Y,Lemley EC,Wang LV,Chen WR

    更新日期：2006-05-01 00:00:00

  • Analysis of the metabolic deterioration of ex vivo skin from ischemic necrosis through the imaging of intracellular NAD(P)H by multiphoton tomography and fluorescence lifetime imaging microscopy.

    abstract：:Ex vivo human skin has been used extensively for cosmeceutical and drug delivery studies, transplantable skin allografts, or skin flaps. However, it has a half-life of a few days due to ischemic necrosis. Traditional methods of assessing viability can be time-consuming and provide limited metabolic information. Using ...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.3466580

    authors： Sanchez WY,Prow TW,Sanchez WH,Grice JE,Roberts MS

    更新日期：2010-07-01 00:00:00

  • Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy.

    abstract：:Fiber-guided ablation of soft tissue with pulsed holmium and thulium lasers was investigated for intraluminal incisions. A bare fiber/tissue-contact application system with a nearly tangential irradiation geometry was first used in vitro on porcine ureter tissue. The efficiency and precision of the method was analyzed...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.429865

    authors： Brinkmann R,Knipper A,Dro Ge G,Schro Er F,Gromoll B,Birngruber R

    更新日期：1998-01-01 00:00:00

  • Hybrid method for fast Monte Carlo simulation of diffuse reflectance from a multilayered tissue model with tumor-like heterogeneities.

    abstract：:We present a hybrid method that combines a multilayered scaling method and a perturbation method to speed up the Monte Carlo simulation of diffuse reflectance from a multilayered tissue model with finite-size tumor-like heterogeneities. The proposed method consists of two steps. In the first step, a set of photon traj...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.17.1.010501

    authors： Zhu C,Liu Q

    更新日期：2012-01-01 00:00:00

  • Model-based spectroscopic analysis of the oral cavity: impact of anatomy.

    abstract：:In order to evaluate the impact of anatomy on the spectral properties of oral tissue, we used reflectance and fluorescence spectroscopy to characterize nine different anatomic sites. All spectra were collected in vivo from healthy oral mucosa. We analyzed 710 spectra collected from the oral cavity of 79 healthy volunt...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.2992139

    authors： McGee S,Mirkovic J,Mardirossian V,Elackattu A,Yu CC,Kabani S,Gallagher G,Pistey R,Galindo L,Badizadegan K,Wang Z,Dasari R,Feld MS,Grillone G

    更新日期：2008-11-01 00:00:00

  • Confocal detection of planar homogeneous and heterogeneous immunosorbent assays.

    abstract：:Optically sectioned detection of fluorescence immunoassays using a confocal microscope enables the creation of both homo- and heterogeneous planar format assays. We report a set assays requiring optically sectioned detection using a model system and analysis procedures for separating signals of a surface layer from an...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.3268772

    authors： Ghafari H,Zhou Y,Ali S,Hanley QS

    更新日期：2009-11-01 00:00:00

  • Adaptive wide-field optical tomography.

    abstract：:We describe a wide-field optical tomography technique, which allows the measurement-guided optimization of illumination patterns for enhanced reconstruction performances. The iterative optimization of the excitation pattern aims at reducing the dynamic range in photons transmitted through biological tissue. It increas...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.18.3.036006

    authors： Venugopal V,Intes X

    更新日期：2013-03-01 00:00:00

  • Fiber optic biosensor for the detection of C-reactive protein and the study of protein binding kinetics.

    abstract：:Application of a fiber optic biosensor (FOB) to the real-time investigation of the interaction kinetics between FITC-conjugated monoclonal sheep anti-human C-reactive protein (CRP) antibody and CRP isoforms on the surface of optical fiber is described. Recently, both the native pentameric CRP (pCRP), an acute phase pr...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.2714029

    authors： Chou C,Hsu HY,Wu HT,Tseng KY,Chiou A,Yu CJ,Lee ZY,Chan TS

    更新日期：2007-03-01 00:00:00

  • New laryngoscope for quantitative high-speed imaging of human vocal folds vibration in the horizontal and vertical direction.

    abstract：:We report the design of a novel laser line-triangulation laryngoscope for the quantitative visualization of the three-dimensional movements of human vocal folds during phonation. This is the first successful in vivo recording of the three-dimensional movements of human vocal folds in absolute values. Triangulation ima...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.3041164

    authors： George NA,de Mul FF,Qiu Q,Rakhorst G,Schutte HK

    更新日期：2008-11-01 00:00:00

  • Toward the clinical application of time-domain fluorescence lifetime imaging.

    abstract：:High-speed (video-rate) fluorescence lifetime imaging (FLIM) through a flexible endoscope is reported based on gated optical image intensifier technology. The optimization and potential application of FLIM to tissue autofluorescence for clinical applications are discussed. ...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.2102807

    authors： Munro I,McGinty J,Galletly N,Requejo-Isidro J,Lanigan PM,Elson DS,Dunsby C,Neil MA,Lever MJ,Stamp GW,French PM

    更新日期：2005-09-01 00:00:00

  • simEye: Computer-based simulation of visual perception under various eye defects using Zernike polynomials.

    abstract：:We describe a computer eye model that allows for aspheric surfaces and a three-dimensional computer-based ray-tracing technique to simulate optical properties of the human eye and visual perception under various eye defects. Eye surfaces, such as the cornea, eye lens, and retina, are modeled or approximated by a set o...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.2357734

    authors： Fink W,Micol D

    更新日期：2006-09-01 00:00:00

  • Tumor-associated macrophages and stromal TNF-α regulate collagen structure in a breast tumor model as visualized by second harmonic generation.

    abstract：:Collagen fibers can be imaged with second harmonic generation (SHG) and are associated with efficient tumor cell locomotion. Preferential locomotion along these fibers correlates with a more aggressively metastatic phenotype, and changes in SHG emission properties accompany changes in metastatic outcome. We therefore ...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.18.8.086003

    authors： Burke RM,Madden KS,Perry SW,Zettel ML,Brown EB 3rd

    更新日期：2013-08-01 00:00:00

  • Combined anatomical optical coherence tomography and intraluminal pressure reveal viscoelasticity of the in vivo airway.

    abstract：:It is hypothesized that the local, viscoelastic (time-dependent) properties of the airway are important to accurately model and ultimately predict dynamic airway collapse in airway obstruction. Toward this end, we present a portable, endoscopic, swept-source anatomical optical coherence tomography (aOCT) system combin...

    journal_title：Journal of biomedical optics

    pub_type： 信件

    doi：10.1117/1.JBO.23.10.100501

    authors： Balakrishnan S,Bu R,Iftimia N,Price H,Zdanski C,Oldenburg AL

    更新日期：2018-10-01 00:00:00

  • Surface plasmon-based infrared spectroscopy for cell biosensing.

    abstract：:Cell morphology is often used as a valuable indicator of the physical condition and general status of living cells. We demonstrate a noninvasive method for morphological characterization of adherent cells. We measure infrared reflectivity spectrum at oblique angle from living cells cultured on thin Au film, and utiliz...

    journal_title：Journal of biomedical optics

    pub_type： 杂志文章

    doi：10.1117/1.JBO.17.8.081409

    authors： Yashunsky V,Lirtsman V,Zilbershtein A,Bein A,Schwartz B,Aroeti B,Golosovsky M,Davidov D

    更新日期：2012-08-01 00:00:00