Abstract：
PURPOSE:To compare the outcome of penetrating keratoplasty (PKP) and deep anterior lamellar keratoplasty (DALK) in the surgical management of keratoconus (KC). PATIENT AND METHODS:A retrospective review was conducted of the medical records of all patients treated with PKP or DALK for KC at University of Iowa Hospitals and Clinics from January 1, 2000, to December 31, 2006. The main outcome measures were visual outcome, graft survival, and complications. Cases with a minimum follow-up of 6 months were included in the statistical analysis. RESULTS:Of 41 eyes that met the inclusion criteria, 30 eyes were treated with PKP and 11 eyes were treated with DALK. The mean follow-up was almost identical for eyes treated with PKP or DALK (21.9 vs. 22.5 months, respectively). At the most recent examination, the mean best spectacle-corrected visual acuity (BSCVA) was 20/28 for the PKP group and 20/29 for the DALK group (P = 0.77). The percentage of eyes that achieved BSCVA of 20/25 or better was higher in the PKP group than in the DALK group (77.3 vs. 45.5%, respectively), but this difference was not statistically significant (P = 0.72). Endothelial rejection occurred in 4 (13.3%) eyes after PKP. Visually significant interface haze occurred in the early postoperative course in 2 (18.2%) eyes after DALK. No cases of late-onset endothelial failure were found in either group. CONCLUSION:Treatment of KC with PKP or DALK is associated with similar visual outcomes, graft survival, and prevalence of sight-threatening complications.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Cohen AW,Goins KM,Sutphin JE,Wandling GR,Wagoner MDdoi
10.1007/s10792-010-9393-9subject
Has Abstractpub_date
2010-12-01 00:00:00pages
675-81issue
6eissn
0165-5701issn
1573-2630journal_volume
30pub_type
杂志文章abstract：PURPOSE:Proliferative vitreoretinopathy in the inferior retina remains clinically challenging. Heavier-than-water intraocular tamponades have been developed to improve inferior tamponading properties, and their chemical compositions have been substantially improved over the years, in parallel with developments in vitre...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-017-0489-3
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:The study aims to evaluate changes in neopterin levels and tryptophan degradation which are induced by Th1-type immune response and nitric oxide metabolism which may be involved in allergic inflammation. METHODS:Serum nitrite, kynurenine, tryptophan and neopterin levels were evaluated in 36 patients with seaso...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0669-1
更新日期：2018-10-01 00:00:00
abstract：:The purpose of the study was to evaluate the outcomes and possible complications of CXL performed with customized epithelial debridement technique to keratoconic corneas with the thinnest pachymetry values less than 400 µm. Nineteen eyes of 19 patients were included. The uncorrected (UCVA) and best corrected visual ac...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0234-3
更新日期：2017-02-01 00:00:00
abstract：:To evaluate the potential benefit of intraocular pressure (IOP) reduction in normal-tension glaucoma (NTG) patients in South Korea. A retrospective, multi-center analysis of Korean NTG patients with 5-years follow-up, typical glaucomatous optic disc and/or visual field changes and no recorded IOP >21 mmHg. Progression...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-011-9463-7
更新日期：2011-10-01 00:00:00
abstract：:Strabismus is a well recognized complication of retrobulbar anesthesia for cataract surgery. This may manifest as either paresis or sometimes contracture (overaction) in the late stage. Management of the patient is tailored to the individual case. Herein, we report a patient with inferior rectus paresis and medial rec...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9342-7
更新日期：2010-08-01 00:00:00
abstract：:Carotid cavernous fistulas (CCFs) can be classified as direct and indirect, depending on their flow rates and their etiology. Both forms can cause the same characteristic ophthalmological symptoms and signs. We analyzed these ocular characteristics and determined the prognostics factors associated with treatment outco...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9550-4
更新日期：2012-04-01 00:00:00
abstract：:We evaluated the in vitro effects of the 1.3 u wavelength of a Nd:YAG laser using a fiberoptic delivery system, with or without sapphire tips on ocular tissue. Conjunctival and retinal adhesions were achieved best with a noncontact technique compared with a contact method. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00155628
更新日期：1987-08-01 00:00:00
abstract：:To analyze the pattern of intermediate uveitis (IU) in a referral center in Tunisia, North Africa. A retrospective, descriptive study of 87 consecutive patients (145 eyes) examined at the Department of Ophthalmology of Monastir (Tunisia) from January 1996 to August 2008. All patients underwent an extensive ocular and ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9352-5
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To compare the preoperative and postoperative measurements of optical low-coherence reflectometry (OLCR) biometry and assessment of its refractive predictability. METHODS:A total of 114 eyes of 102 patients who underwent cataract treatment were prospectively examined. The axial length (AL), central corneal thi...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0952-9
更新日期：2019-06-01 00:00:00
abstract：:The purpose of this study was to evaluate the presence of Toxoplasmosis gondii in samples of peripheral blood from patients with varying etiologies of uveitis. Whole blood from patients with different forms of uveitis was tested for the presence of T. gondii using real-time PCR targeting the well-characterized 529 bp ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0221-8
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To demonstrate differences in optic nerve head (ONH), retinal nerve fiber layer (RNFL), and macular thickness in patients with internal carotid artery (ICA) stenosis using spectral domain optical coherence tomography (SD-OCT). METHODS:A case-controlled study was conducted in 31 patients with a diagnosis of uni...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01642-8
更新日期：2020-11-10 00:00:00
abstract：:Diplopia is a very disturbing condition that has been reported as a complication of several surgical procedures. The following review aims to identify the ocular and nonocular surgical techniques more often associated with this undesirable result. Diplopia is reported as an adverse outcome of some neurosurgical proced...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9927-7
更新日期：2014-08-01 00:00:00
abstract：:The purpose of the study was to compare the accuracy of various biometric formulas for predicting postoperative refraction determined using applanation A-scan ultrasound. This retrospective comparative study included 485 eyes that underwent uneventful phacoemulsification with intraocular lens (IOL) implantation. Appla...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0195-6
更新日期：2016-10-01 00:00:00
abstract：:The association between HLA-A29 and birdshot chorioretinopathy is the strongest of all associations between HLA and disease. Determination of HLA-A29 is even of diagnostic significance. The association between HLA-B27 and acute anterior uveitis (AAU) is much weaker, but B27 positive AAU may be considered as a distinct...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00163552
更新日期：1990-10-01 00:00:00
abstract：:Invasive aspergillosis is a rare disease and is often misdiagnosed. The clinical course is quite aggressive and it is a potentially fatal disease. We report a case of invasive aspergillosis involving the dura mater and optic nerves which was successfully treated with voriconazole, even though the patient had residual ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9730-x
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:The aim of this study was to evaluate the corneal biomechanical parameters in patients with ankylosing spondylitis (AS) and to compare them with the healthy subjects. METHODS:Sixty patients with AS (study group) and 60 healthy subjects (control group) were enrolled in this prospective study. The study group wa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0368-3
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:The objective of this study is to examine the morphometry of the lacrimal drainage system with reference to bony landmarks in the vicinity. METHODS:Twenty midsaggitalized heads obtained from sixteen preserved cadavers were studied. Measurements involved detailed morphometry of anterior and posterior lacrimal c...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0753-6
更新日期：2018-12-01 00:00:00
abstract：:The retinal toxicity of vancomycin in infusion solution used in vitrectomy and lensectomy was investigated in rabbit eyes by means of electroretinography and histologic study (light microscopy). Concentrations of 8 micrograms/ml, 16 micrograms/ml, and 32 micrograms/ml of vancomycin in balanced salt solution caused no ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00942780
更新日期：1993-04-01 00:00:00
abstract：:Onchocerciasis is a major blinding disease affecting at least 28 million people in Africa and Latin America. Although a large-scale vector control program has been highly successful in limiting transmission of infection in West Africa, there has not been a satisfactory form of treatment available for those already inf...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136735
更新日期：1987-12-01 00:00:00
abstract：:To evaluate the role of brimonidine (BMD), an alpha-2 agonist, in the management of clinically significant macular edema (CSME) in diabetic maculopathy with ischemic changes. A prospective, randomized controlled trial including 30 eyes of 30 metabolically stable diabetic patients with CSME showing fundus fluorescein a...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-013-9871-y
更新日期：2014-08-01 00:00:00
abstract：PURPOSE:To assess the comparative efficacy and the long-term cost-utility of alternative minimally invasive glaucoma surgeries (MIGSs) when combined with cataract surgery in patients with primary open-angle glaucoma (POAG). METHODS:Treatment effects, as measured by the 1-year reduction in intraocular pressure (IOP), w...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01314-7
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:To identify baseline optical coherence tomography (OCT) factors in ischemic central retinal vein occlusion (CRVO) that predict response to bevacizumab injections. METHODS:Patients underwent OCT at diagnosis and the central macular thickness, subretinal fluid width and height as well as the presence of intraret...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01604-0
更新日期：2020-10-22 00:00:00
abstract：PURPOSE:To study the connective tissue (CT) structure of upper eyelid skin of primary open-angle glaucoma (POAG) patients. PATIENTS AND METHODS:Forty-seven patients aged 47-91 expecting blepharoplasty formed 3 groups: group 1 [16 subjects without POAG, median age 55 years (interquartile range 54-55.5)], group 2 [12 su...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1035-7
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:Recently, the vasodilator relaxin 2 has been introduced as a treatment for acute heart failure. However, its role on vessels of the eye and intraocular pressure (IOP) remains unclear though it has been hypothesized to induce a decrease IOP after intramuscular injection in humans. We aimed to test whether the ho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0884-4
更新日期：2019-04-01 00:00:00
abstract：:The choroidal vascular bed has many interesting features such as relatively wide but flat capillaries, fenestrated capillary walls and an enormous blood flow. The high flow rate results in a high oxygen tension in the tissue and is also of importance in the temperature control of the eye. The capillary wall is permeab...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00127638
更新日期：1983-02-01 00:00:00
abstract：:Transvitreal pars plana sclerotomy using the contact Nd:YAG laser with a sapphire probe was performed on a group of rabbit eyes and compared with a similar procedure performed with a Ziegler knife. Although the intraocular pressure (IOP) was lowered in both groups of animals, the reduction was greater and more lasting...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130620
更新日期：1988-01-01 00:00:00
abstract：:The cone dystrophies can be subdivided into 3 functional stages: central cone disease, peripheral cone disease and diffuse cone disease, respectively. In the patient material of our clinic the sex distribution of patients presenting with te diffuse cone disease stage was abnormal: 22 males and 3 females. The authors s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00155631
更新日期：1987-08-01 00:00:00
abstract：:The purpose of this study was to determine the causes of childhood visual impairment and blindness in students of a school for blind children, to determine how many students had some residual vision, and to evaluate any unmet low-vision care. A survey of students in the blind school was conducted in two parts in May-J...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9134-x
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:To elucidate the role of trabeculectomy in advanced glaucoma. MATERIALS AND METHODS:Only patients with primary open-angle glaucoma were selected. All patients who had cup-disc ratio of 0.9 or a near-total cupping were given a trial of aggressive maximum medical therapy for IOP control for at least 4 weeks. Tar...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0797-7
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:To evaluate the performance of full-thickness (FT) versus partial-thickness (PT) sutures in a full-thickness corneal wound in an animal model. METHODS:This is a prospective, experimental, comparative, longitudinal study. A 6-mm linear, full-thickness corneal incision was performed on the right eye of eight dom...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01585-0
更新日期：2021-01-01 00:00:00
