Abstract：
PURPOSE:To elucidate the role of trabeculectomy in advanced glaucoma. MATERIALS AND METHODS:Only patients with primary open-angle glaucoma were selected. All patients who had cup-disc ratio of 0.9 or a near-total cupping were given a trial of aggressive maximum medical therapy for IOP control for at least 4 weeks. Target IOP was defined as ≤ 12 mm Hg. Patients who showed progression were included in the study. A total of 10 patients were selected. Trabeculectomy was performed using limbal-based conjunctival flap. Patients were followed up for a period of 2 years for visual acuity, intraocular pressure, visual fields, slit-lamp biomicroscopy and bleb morphology. RESULTS:Mean preoperative intraocular pressure on five drugs was 21.7 ± 3.8 mm Hg (range 18-27 mm Hg) on maximum medical therapy. Mean post-operative intraocular pressure was 11 ± 1.78 mm Hg (range 9-13 mm Hg) and 11 ± 1.92 mm Hg (range 9-14 mm Hg) at 1 month and 6 months post-operatively, respectively. Post-operatively, the visual acuity remained stable in 17 patients. It dropped by 1 Snellen line in 2 patients and 2 Snellen lines in 1 patient, respectively, over a period of 6 months and later improved to 6/6P following cataract surgery. There was no defined visual field progression in any of the 20 patients. CONCLUSION:Besides being a cost-effective alternative to medical management, trabeculectomy not only provides a better IOP control but also has a high safety profile when performed by an experienced surgeon.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Sethi HS,Naik MP,Saluja Kdoi
10.1007/s10792-017-0797-7subject
Has Abstractpub_date
2019-01-01 00:00:00pages
137-143issue
1eissn
0165-5701issn
1573-2630pii
10.1007/s10792-017-0797-7journal_volume
39pub_type
杂志文章abstract：:Preliminary results of a larger investigation on correlation between Retinal Nerve Fiber Layer Defects (RNFL) and Automated Perimetry (AP) are presented. A group of ocular hypertensive patients was recruited and a cross-section, randomized study was carried out. The group was composed of 54 eyes from 28 patients; 15 m...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00917968
更新日期：1992-09-01 00:00:00
abstract：AIMS/BACKGROUND:We evaluated the retinal toxicity of spartanamicin B and its efficacy in a rabbit model of Candidal endophthalmitis. METHODS:Toxicity. Fourteen albino rabbit eyes were injected intravitreally with spartanamicin B (1, 2, 5, 10, 25, 50, and 100 microg); 2 eyes received the vehicle alone. Efficacy. Ten ra...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006191629625
更新日期：1998-01-01 00:00:00
abstract：:The aim of this study was to evaluate tear osmolarity and ocular comfort with two different types of hydrogel daily disposable lenses. The right eyes of 15 first-time contact lens users were included in this prospective study. All eyes wore hilafilcon B silicone hydrogel contact lenses for 8 h (group 1). After 1 week ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9556-y
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PE...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0498-2
更新日期：2018-04-01 00:00:00
abstract：:To analyze the association between Eales disease, histocompatibility leukocyte antigen alleles (HLA-A/B, HLA-DRB/DQB) and tuberculosis infection, and to explore susceptible genes and protective genes associated with Eales disease and tuberculosis infection in a population of Han nationals from Zunyi City in Guizhou Pr...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9718-6
更新日期：2013-10-01 00:00:00
abstract：:The aim of this study is to compare a portable spectral domain optical coherence tomography (SD-OCT) device with a non-portable SD-OCT for the identification of anterior chamber angle parameters based on location of Schwalbe's line (SL) and to measure their reproducibility. 99 eyes from 46 normal, healthy participants...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0223-6
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To report the fluorescein fundus angiographic (FFA) findings in the different clinical stages of Vogt-Koyanagi-Harada (VKH) patients. METHODS:Retrospective, transversal and descriptive study. All patients underwent FFA at least in one occasion. Patients with incomplete clinical files or a deficient FFA were ex...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-006-9027-4
更新日期：2007-04-01 00:00:00
abstract：PURPOSE:Ripasudil accelerates aqueous humour drainage along the trabecular meshwork-Schlemm's canal route and has been approved for clinical use in Japan. We retrospectively investigated the efficacy and safety of adding ripasudil to existing treatment regimens to reduce intraocular pressure (IOP) in patients with glau...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0427-9
更新日期：2018-02-01 00:00:00
abstract：:The purpose of this study is to evaluate whole lysyl oxidase like 1 (LOXL1) gene by sequence analysis in Turkish patients with exfoliation glaucoma (XFG). A total of 48 (35 male, 13 female) patients with XFG were enrolled. Besides routine ophthalmological examination, peripapillary retinal nerve fibre layer (RNFL) ana...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0174-y
更新日期：2016-10-01 00:00:00
abstract：:Postural behaviour of intraocular pressure (IOP) was studied in 29 glaucomatous eyes before and after argon laser trabeculoplasty (ALT) and compared with that of 60 normal eyes. Although argon laser trabeculoplasty was successful in lowering the IOP below 21 mm Hg, it produced little effect on the postural behaviour o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00916436
更新日期：1992-05-01 00:00:00
abstract：:Sarcoidosis is a multisystem disease characterized by enhanced immune responses at sites of involvement. To elucidate the immunopathogenesis of ophthalmic lesions, cell infiltrates in biopsies from conjunctiva and other tissues involved (lungs, lymph nodes, skin) were studied in 26 patients with active sarcoidosis in ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00131162
更新日期：1990-01-01 00:00:00
abstract：:Insulin-like growth factor-1 (IGF-1) is altered in several neurodegenerative diseases, the association between serum IGF-1 levels and glaucoma has not been evaluated. This study was designed to evaluate whether serum IGF-1 levels are different in patients with Pseudoexfoliation (PEX) with or without glaucoma. The stud...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0271-y
更新日期：2017-04-01 00:00:00
abstract：PURPOSE:To report a case of toxic optic neuropathy caused by an ocular bee sting. METHODS:Case report and literature review. RESULTS:A 44-year-old female presented with no light perception vision 2 days after a corneal bee sting in her right eye. She was found to have diffuse cornea edema with overlying epithelial de...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0978-z
更新日期：2019-07-01 00:00:00
abstract：:A 37 year old woman presented with a bilateral vitritis. 4 months previously, she had developed in her left eye a necrotizing retinitis compatible with acute retinal necrosis (ARN). A trial of Acyclovir was unsuccessful as were systemic steroids. Over the following 2 months the vitritis worsened. The patient underwent...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00163568
更新日期：1990-10-01 00:00:00
abstract：:I have developed two protective caps that fit on the viewing windows of the indirect ophthalmoscope. These caps contain filters that absorb the argon laser beam and protect the operator's eyes during endolaser treatment. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00225937
更新日期：1986-04-01 00:00:00
abstract：:Infants have been known occasionally to stare without blinking for almost a minute. This puts great demands on the stability of their tear-film. To verify the stability of infant tears, we performed biophysical experiments on Meibomian gland secretion, which forms the outermost layer of the tear-film. The secretion wa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00919408
更新日期：1994-01-01 00:00:00
abstract：:To report a unusual case of an isolated traumatic stellated tarso-conjunctival laceration located in the upper left eyelid without eyelid margin involvement and with normal ocular examination. A 19 year-old male wounded by a bokken (wooden katana) while practicing a sham duel had an isolated eyelid tarso-conjunctival ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9573-x
更新日期：2012-08-01 00:00:00
abstract：PURPOSE:To compare the efficacy and safety of two intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents, ranibizumab and aflibercept, for the treatment of vascularized pigment epithelium detachment (vPED) due to age-related macular degeneration (AMD) in a follow-up time of 12 months. METHODS:Particip...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0833-2
更新日期：2019-02-01 00:00:00
abstract：PURPOSE:To evaluate rotational stability and visual and refractive outcomes of supplementary toric IOLs (Sulcoflex Toric 653T, Rayner Intraocular Lenses Ltd) for residual astigmatic refractive error in pseudophakic eyes. METHODS:A retrospective interventional case series was conducted in a single surgeon practice. Cha...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1027-7
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:To determine whether there are angiographic differences among normal, preperimetric and advanced glaucoma eyes using indocyanine green angiography with SLO. This method was chosen because of its sensibility to detect peripapillary capillary vessels. METHODS:Scanning laser opthalmoscopy was preformed on normal ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014431404096
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To evaluate the changes on optical coherence tomography angiography (OCTA) in macula-off rhegmatogenous retinal detachments (RRD) treated with pars plana vitrectomy (PPV) and silicone oil (SO) 5000-cSt tamponade. MATERIALS AND METHOD:Forty-five eyes with macula-off RRD treated with PPV and SO tamponade were en...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01516-z
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:We aimed to analyze the clinical characteristics of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome. Furthermore, we aimed to correlate the number and location of retinal aneurysms with the size of retinal non-perfusion area and neovascularization. METHODS:Six patients with IRVAN ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0962-7
更新日期：2019-07-01 00:00:00
abstract：AIM:To evaluate the effect of acute anaerobic exercise on macular perfusion measured by swept-source optical coherence tomography angiography (SS-OCTA) in young football players. MATERIALS AND METHODS:Football players with ages between 18 and 20 years were included into the study. After a detailed ophthalmological exa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01303-w
更新日期：2020-06-01 00:00:00
abstract：:The unifying principle underlying this classification system is: The more posterior the disease and the greater the amount of involved retinal vascular tissue, the more serious the disease. The staging of the disease at any given location expresses the natural history and evolution of events at the border between vasc...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136454
更新日期：1985-04-01 00:00:00
abstract：PURPOSE:To report a case of Pseudomonas aeruginosa endophthalmitis with choroidal abscess formation in a patient with bronchiectasis. METHODS:Case report. RESULTS:A 75-year-old gentleman with bronchiectasis and P. aeruginosa pneumonia developed painless loss of right eye vision. The patient had previously undergone b...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9126-x
更新日期：2008-08-01 00:00:00
abstract：:The purpose of this study was to compare the keratometry (K) values obtained by the Scheimpflug camera combined with placido-disk corneal topography (Sirius) and optical biometry (Lenstar) for intraocular lens (IOL) power calculation before the cataract surgery, and to evaluate the accuracy of postoperative refraction...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0330-4
更新日期：2017-08-01 00:00:00
abstract：:The purpose is to report a case of Candida interface infection after deep anterior lamellar keratoplasty (DALK). A 23-year-old female patient underwent DALK surgery in the left eye for keratoconus. Four weeks after the surgery, she presented with asymptomatic white-cream colored deposits at the graft-host interface. E...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9545-1
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:A case report of recurrent unilateral granulomatous iridocyclitis with ocular hypertension without retinitis caused by cytomegalovirus (CMV) in an immunocompetent patient. METHODS:Aqueous humor was analysed by multiplex PCR to detect viral DNA, and real-time PCR was used to evaluate virus copies before and ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9090-5
更新日期：2007-12-01 00:00:00
abstract：PURPOSE:Retinal vascular abnormalities are associated with choroidal melanoma. Although tumor ischemia, resulting in soluble angiogenic factor production, is a proposed etiology of these abnormalities, other sources of ischemia may also contribute. Mushroom-shaped choroidal melanomas have increased loss of the overlyin...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1021170402679
更新日期：2001-01-01 00:00:00
abstract：:Corneal ulcer is a devastating corneal disease which is potentially sight-threatening and conventionally is treated by topical antibiotics and in some cases with more invasive procedures such as keratoplasty. The aim of this study is to evaluate the efficacy of corneal collagen cross-linking in resistant corneal ulcer...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-012-9633-2
更新日期：2013-02-01 00:00:00
