Collagen cross-linking for resistant corneal ulcer.

Abstract:

:Corneal ulcer is a devastating corneal disease which is potentially sight-threatening and conventionally is treated by topical antibiotics and in some cases with more invasive procedures such as keratoplasty. The aim of this study is to evaluate the efficacy of corneal collagen cross-linking in resistant corneal ulcers. Ten patients with resistant infectious corneal ulcers who had not responded properly to maximal treatment with topical and subconjunctival antibiotics were enrolled in the study and underwent classic corneal collagen cross-linking with riboflavin and UV-A under sterile conditions in the operating room and were followed up regularly. The result was healing and scar formation with improvement of vision in all patients except for two who underwent enucleation and tectonic penetrating keratoplasty. Corneal collagen cross-linking is a viable therapeutic option for treatment of corneal ulcers and can be used as an adjuvant for conventional treatment in resistant cases.

journal_name

Int Ophthalmol

authors

Sorkhabi R,Sedgipoor M,Mahdavifard A

doi

10.1007/s10792-012-9633-2

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

61-6

issue

1

eissn

0165-5701

issn

1573-2630

journal_volume

33

pub_type

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