Abstract:
PURPOSE:The authors investigated the use of dapiprazole, an alpha-adrenergic blocking agent, in preventing pigment release and IOP increase after exercise in patients affected with PDS. METHODS:Three young myopic males (31, 34 and 35 years old) affected with pigmentary dispersion syndrome performed 30 minutes of jogging on a computerized treadmill. Telemetric heartbeat measurement was performed to obtain constant pulse rate training. Computerized tonography and IOP measurement were performed 10 minutes after the exercise. After one month the patients repeated the same exercise after pre-treatment with dapiprazole 0.5% eyedrops (one drop 30, 20 and 10 minutes before the exercise). Ten minutes after the exercise IOP measurements and computerized tonography were repeated. RESULTS:After 30 minutes of exercise IOP measurements showed values ranging from 19 to 45 mmHg (mean 30.33; SD 8.73). Computerized tonography C values after exercise ranged from 0.04 to 0.16 (mean 0.09; SD 0.04). After pre-treatment with dapiprazole 0.5% eyedrops, IOP values ranged from 18 to 28 mmHg (mean 23.33; SD 3.44) and tonography C values ranged from 0.10 to 0.20 (mean 0.14; SD 0.03). CONCLUSIONS:The study supports the concept that exercise-induced pigment release temporarily obstructs the acqueous outflow channels, causing IOP increase in some patients with PDS. Pre-treatment with dapiprazole was useful in reducing IOP spikes and in increasing tonographic total outflow facility after exercise. The absence of induced myopia and the lack of dangerous vitreoretinal tractions on retinal periphery make dapiprazole a safe method to reduce exercise-induced pigment dispersion.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Mastropasqua L,Carpineto P,Ciancaglini M,Gallenga PEdoi
10.1007/BF00130855subject
Has Abstractpub_date
1995-01-01 00:00:00pages
359-62issue
6eissn
0165-5701issn
1573-2630journal_volume
19pub_type
杂志文章abstract:PURPOSE:To report a case of toxic optic neuropathy caused by an ocular bee sting. METHODS:Case report and literature review. RESULTS:A 44-year-old female presented with no light perception vision 2 days after a corneal bee sting in her right eye. She was found to have diffuse cornea edema with overlying epithelial de...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-018-0978-z
更新日期:2019-07-01 00:00:00
abstract::To determine the optimal area of retinal photocoagulation required for suppressing active neovascularisation (NVI) associated with diabetic retinopathy. We studied 1 eye each of 4 patients in whom active NVI was ophthalmoscopically shown to have been suppressed by additional photocoagulation. These patients initially ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9802-y
更新日期:2014-10-01 00:00:00
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journal_title:International ophthalmology
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doi:10.1007/s10792-007-9111-4
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abstract::Various techniques which use monoclonal antibodies to detect Chlamydia trachomatis in clinical specimens are reviewed. An investigation comparing the efficacy of immunofluorescent staining with Giemsa staining in detecting Chlamydia in conjunctival scrapings from cases of active trachoma is presented. Sixty-two eyes o...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00133786
更新日期:1988-01-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-021-01707-2
更新日期:2021-01-22 00:00:00
abstract:PURPOSE:To investigate complex and different phenotypes in seven Chinese patients diagnosed with Bardet-Biedl syndrome (BBS) and carrying pathogenic mutations. METHODS:Seven unrelated BBS patients were enrolled. Their medical and ophthalmic histories were reviewed, and comprehensive clinical examinations, such as fund...
journal_title:International ophthalmology
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To evaluate the cognitive performance of patients with glaucoma and compare it to individuals with Alzheimer's disease (AD). METHODS:This is a prospective, cross-sectional and case-control study. All subjects were assessed using the Mini-Mental State Examination (MMSE) and its subtests verbal fluency, word lis...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0658-4
更新日期:2018-10-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
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更新日期:2011-12-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/b:inte.0000018521.88103.17
更新日期:2004-01-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章,评审
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更新日期:2011-04-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1005892426045
更新日期:1997-01-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章,评审
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更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:Vogt-Koyanagi-Harada syndrome (VKHS) is an inflammatory systemic autoimmune disease principally affecting pigmented tissues in the ocular, auditory, integumentary and central nervous systems. Patients are generally women in the fourth decade of life. The prognosis is correlated mainly with the time between...
journal_title:International ophthalmology
pub_type: 杂志文章
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更新日期:2018-04-01 00:00:00
abstract::A series of pathological conditions such as pupillary block glaucoma, angle block glaucoma, acoria, pupillary membranes and goniosynechias of various origins have been treated successfully by means of pulses emitted from a Nd:YAG Q-switched laser above optical breakdown threshold. Since linear absorption is not requir...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00130696
更新日期:1981-05-01 00:00:00
abstract::The melanocytoma of the optic disc is a deeply-pigmented tumor located on the optic nerve head. In contrast to malignant melanoma, it appears to occur in equal frequency in whites and non-whites. Histologically, it consists of deeply-pigmented plump nervus cells with benign characteristics. No treatment is usually nec...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00133275
更新日期:1978-09-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01463-9
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:The objective is to report a rare case of asymptomatic penetrating injury with a copper foreign body found during an examination for cataract surgery. METHOD:A case report. RESULTS:A 73-year-old woman had vision loss. Examination by pupil dilation disclosed a dark-brown metallic mass located under the anterio...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9074-5
更新日期:2007-10-01 00:00:00
abstract::Trichiasis/Entropion are the severe consequences of chronic trachoma during early life. Blindness and vision loss is preventable with timely lid surgery to correct trichiasis. In a trachoma hyperendemic region of Central Tanzania, a two year follow-up survey was conducted among 205 women with trichiasis to determine t...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00919249
更新日期:1994-01-01 00:00:00
abstract::To investigate the efficacy of anti-tuberculous therapy and systemic corticosteroids in patients suffering from active presumed tuberculous choroiditis by the assessment of central retinal sensitivity and fixation characteristics. Six patients (six eyes) with active presumed tuberculous choroiditis were treated with a...
journal_title:International ophthalmology
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更新日期:2010-10-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10792-013-9871-y
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To review the multimodal imaging patterns of posterior syphilitic uveitis. METHODS:A systematic review. RESULTS:The percentage of syphilis has started to increase again: The World Health Organization has reported 12 million new cases of syphilis each year. In addition, syphilis was responsible for 0.3% of dea...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-020-01285-9
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To present the long-term results of therapeutic keratoplasty for microbial keratitis in moderate to advanced phases. METHODS:The medical records of 44 patients who underwent therapeutic keratoplasty for microbial keratitis at the ophthalmology clinic of a training and research hospital between June 2012 and Ma...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01538-7
更新日期:2020-12-01 00:00:00
abstract::A case of keratomycosis caused by Alternaria species in a patient with glaucoma is reported. A 55-year-old Japanese man who had been followed for developmental glaucoma presented with corneal ulcer in his right eye, which did not respond to antibacterial agents. There was no history of traumatic episode. Culture on po...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9260-0
更新日期:2009-12-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01498-y
更新日期:2020-11-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01603-1
更新日期:2020-10-14 00:00:00
abstract::Roussel and Fankhauser have proposed contact glasses with a collecting front surface centred on the bundle focus for use with high power lasers. We demonstrate here that the main contribution to the gain in energy density within the focus spot must be attributed to the front surface of the glass. This is at variance w...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00165111
更新日期:1984-06-01 00:00:00
abstract::The study aims to determine the progression of gyrate atrophy by measuring the area growth of chorioretinal atrophic lesions using ultra-wide-field images (UWFI). A retrospective, observational, and comparative study was conducted and UWFI (200°) were obtained from two patients with gyrate atrophy at baseline and foll...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-015-0085-3
更新日期:2016-02-01 00:00:00
abstract::A 61-year-old male developed recurrent anterior uveitis over a period of 8 months after an uncomplicated phacoemulsification and posterior chamber intraocular lens implantation surgery. This was subsequently found to be due to a retained lens fragment in the anterior segment, with complete resolution following surgica...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9279-2
更新日期:2010-02-01 00:00:00
abstract::Risk factors for corneal transplantation failure include both immunologic factors, such as graft rejection, corneal neovascularization, and peripheral anterior synechiae, as well as non-immunologic factors, such as ocular surface disorders (OSD) and glaucoma. This review highlights the necessity of having healthy ocul...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-007-9127-9
更新日期:2008-06-01 00:00:00