The effectiveness of dapiprazole in preventing exercise-induced IOP increase in patients with pigmentary dispersion syndrome.

Abstract:

PURPOSE:The authors investigated the use of dapiprazole, an alpha-adrenergic blocking agent, in preventing pigment release and IOP increase after exercise in patients affected with PDS. METHODS:Three young myopic males (31, 34 and 35 years old) affected with pigmentary dispersion syndrome performed 30 minutes of jogging on a computerized treadmill. Telemetric heartbeat measurement was performed to obtain constant pulse rate training. Computerized tonography and IOP measurement were performed 10 minutes after the exercise. After one month the patients repeated the same exercise after pre-treatment with dapiprazole 0.5% eyedrops (one drop 30, 20 and 10 minutes before the exercise). Ten minutes after the exercise IOP measurements and computerized tonography were repeated. RESULTS:After 30 minutes of exercise IOP measurements showed values ranging from 19 to 45 mmHg (mean 30.33; SD 8.73). Computerized tonography C values after exercise ranged from 0.04 to 0.16 (mean 0.09; SD 0.04). After pre-treatment with dapiprazole 0.5% eyedrops, IOP values ranged from 18 to 28 mmHg (mean 23.33; SD 3.44) and tonography C values ranged from 0.10 to 0.20 (mean 0.14; SD 0.03). CONCLUSIONS:The study supports the concept that exercise-induced pigment release temporarily obstructs the acqueous outflow channels, causing IOP increase in some patients with PDS. Pre-treatment with dapiprazole was useful in reducing IOP spikes and in increasing tonographic total outflow facility after exercise. The absence of induced myopia and the lack of dangerous vitreoretinal tractions on retinal periphery make dapiprazole a safe method to reduce exercise-induced pigment dispersion.

journal_name

Int Ophthalmol

authors

Mastropasqua L,Carpineto P,Ciancaglini M,Gallenga PE

doi

10.1007/BF00130855

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

359-62

issue

6

eissn

0165-5701

issn

1573-2630

journal_volume

19

pub_type

杂志文章
  • Predicting visual function after an ocular bee sting.

    abstract:PURPOSE:To report a case of toxic optic neuropathy caused by an ocular bee sting. METHODS:Case report and literature review. RESULTS:A 44-year-old female presented with no light perception vision 2 days after a corneal bee sting in her right eye. She was found to have diffuse cornea edema with overlying epithelial de...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-018-0978-z

    authors: Ahmed M,Lee CS,McMillan B,Jain P,Wiley L,Odom JV,Leys M

    更新日期:2019-07-01 00:00:00

  • Optimal area of retinal photocoagulation necessary for suppressing active iris neovascularisation associated with diabetic retinopathy.

    abstract::To determine the optimal area of retinal photocoagulation required for suppressing active neovascularisation (NVI) associated with diabetic retinopathy. We studied 1 eye each of 4 patients in whom active NVI was ophthalmoscopically shown to have been suppressed by additional photocoagulation. These patients initially ...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-013-9802-y

    authors: Shiraya T,Kato S,Shigeeda T

    更新日期:2014-10-01 00:00:00

  • Endogenous endophthalmitis complicating Klebsiella pneumoniae liver abscess in Europe: case report.

    abstract:PURPOSE:To report the first European case of endogenous endophthalmitis secondary to a liver abscess due to Klebsiella pneumoniae expressing MagA gene. METHODS:A 33-year-old diabetic patient was admitted for fever and right upper quadrant abdominal pain. Abdominal computed tomography and laboratory studies were perfor...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-007-9111-4

    authors: Karama EM,Willermain F,Janssens X,Claus M,Van den Wijngaert S,Wang JT,Verougstraete C,Caspers L

    更新日期:2008-04-01 00:00:00

  • Monoclonal antibodies in the laboratory diagnosis of trachoma.

    abstract::Various techniques which use monoclonal antibodies to detect Chlamydia trachomatis in clinical specimens are reviewed. An investigation comparing the efficacy of immunofluorescent staining with Giemsa staining in detecting Chlamydia in conjunctival scrapings from cases of active trachoma is presented. Sixty-two eyes o...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00133786

    authors: Taylor PB,Burd EM,Tabbara KF

    更新日期:1988-01-01 00:00:00

  • Evaluating CO2 laser-assisted sclerectomy surgery with mitomycin C combined with or without phacoemulsification in adult Asian glaucoma subjects.

    abstract:PURPOSE:To evaluate and compare outcomes of CO2 laser-assisted sclerectomy surgery (CLASS) with mitomycin C (MMC) combined with or without phacoemulsification in adult Asian glaucoma patients. DESIGN:Retrospective, comparative study. METHODS:Adult Asian glaucoma patients who underwent CLASS alone or combined with pha...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-021-01707-2

    authors: Ho DCW,Perera SA,Hla MH,Ho CL

    更新日期:2021-01-22 00:00:00

  • Characteristics of genotype and phenotype in Chinese patients with Bardet-Biedl syndrome.

    abstract:PURPOSE:To investigate complex and different phenotypes in seven Chinese patients diagnosed with Bardet-Biedl syndrome (BBS) and carrying pathogenic mutations. METHODS:Seven unrelated BBS patients were enrolled. Their medical and ophthalmic histories were reviewed, and comprehensive clinical examinations, such as fund...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01415-3

    authors: Tao T,Wang L,Chong W,Yang L,Li G

    更新日期:2020-09-01 00:00:00

  • Cognitive evaluation of patients with glaucoma and its comparison with individuals with Alzheimer's disease.

    abstract:PURPOSE:To evaluate the cognitive performance of patients with glaucoma and compare it to individuals with Alzheimer's disease (AD). METHODS:This is a prospective, cross-sectional and case-control study. All subjects were assessed using the Mini-Mental State Examination (MMSE) and its subtests verbal fluency, word lis...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-017-0658-4

    authors: Maurano STP,da Silva DJ,Ávila MP,Magacho L

    更新日期:2018-10-01 00:00:00

  • Intraoperative clouding of a posterior chamber intraocular lens.

    abstract::The glistening and delayed opacification of intraocular lenses (IOLs) has been reported in literature as a late and permanent change in the acrylic IOL due to temperature change. We report a case in which clouding and opacification of an IOL occurred intraoperatively within a few seconds of implantation into the capsu...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-011-9481-5

    authors: Tyagi P,Shah N,Jabir M

    更新日期:2011-12-01 00:00:00

  • Contact lens, hyperopia and endothelial changes. A case report.

    abstract:INTRODUCTION:We report on a 62-year-old healthy woman who suffered from bilateral predescemetic opacities, where the underlying disorder could not be identified. She had bilateral keratopathy with corneal edema, a diffuse predescemetic avascular haze and deszemetic folds. Because of high hyperopia (right +7.50/left +7....

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1023/b:inte.0000018521.88103.17

    authors: Roters S,Severin M,Konen W,Szurman P,von Domarus D,Krieglstein GK

    更新日期:2004-01-01 00:00:00

  • Lipoid proteinosis of Urbach and Weithe: case report and a brief review of the literature.

    abstract::Lipoid proteinosis is a rare disorder involving multiple organ systems. The ocular manifestations are usually trivial, but greatly aid in the diagnosis. We describe a patient who presented to us with typical moniliform blepharosis. A brief description of relevance to the ophthalmologist and review of the literature fo...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-011-9417-0

    authors: Sainani MP,Muralidhar R,Parthiban K,Vijayalakshmi P

    更新日期:2011-04-01 00:00:00

  • Identification of anterior chamber angle parameters with a portable SD-OCT device compared to a non-portable SD-OCT.

    abstract::The aim of this study is to compare a portable spectral domain optical coherence tomography (SD-OCT) device with a non-portable SD-OCT for the identification of anterior chamber angle parameters based on location of Schwalbe's line (SL) and to measure their reproducibility. 99 eyes from 46 normal, healthy participants...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-016-0223-6

    authors: Akil H,Marion K,Dastiridou A,Jenkins D,Kramer B,Francis BA,Chopra V

    更新日期:2017-02-01 00:00:00

  • The effects of long-term topical glaucoma medication on conjunctival impression cytology.

    abstract::Long-term use of topical drugs can induce changes in the conjunctiva and ocular surface. To determine the conjunctival changes resulting from topical glaucoma medication, patients with glaucoma were selected and classified into seven groups, according to the medication received: 24 eyes were treated with betaxolol, 20...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1023/a:1005892426045

    authors: Turaçli E,Budak K,Kaur A,Mizrak B,Ekinci C

    更新日期:1997-01-01 00:00:00

  • Bilateral acute angle closure glaucoma and myopic shift by topiramate-induced ciliochoroidal effusion: case report and literature review.

    abstract:PURPOSE:To report two cases of ciliochoroidal effusion after the usage of topiramate. CASES:Two middle-aged women experienced sudden onset of acute glaucoma and acquired myopia after taking topiramate. Ultrasound biomicroscopy demonstrated bilateral ciliochoroidal effusion and angle closure. The A-scan ultrasonography...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-017-0740-y

    authors: Lan YW,Hsieh JW

    更新日期:2018-12-01 00:00:00

  • A challenged case of Vogt-Koyanagi-Harada syndrome: when dermatological manifestations came first.

    abstract:INTRODUCTION:Vogt-Koyanagi-Harada syndrome (VKHS) is an inflammatory systemic autoimmune disease principally affecting pigmented tissues in the ocular, auditory, integumentary and central nervous systems. Patients are generally women in the fourth decade of life. The prognosis is correlated mainly with the time between...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-017-0504-8

    authors: Coutinho I,Pedrosa C,Santos C,Pina S,Lisboa M,Bernardo M,Prieto I

    更新日期:2018-04-01 00:00:00

  • Clinical studies on the efficiency of high power laser radiation upon some structures of the anterior segment of the eye. First experiences of the treatment of some pathological conditions of the anterior segment of the human eye by means of a Q-switched

    abstract::A series of pathological conditions such as pupillary block glaucoma, angle block glaucoma, acoria, pupillary membranes and goniosynechias of various origins have been treated successfully by means of pulses emitted from a Nd:YAG Q-switched laser above optical breakdown threshold. Since linear absorption is not requir...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00130696

    authors: Fankhauser F,Roussel P,Steffen J,Van der Zypen E,Chrenkova A

    更新日期:1981-05-01 00:00:00

  • Melanocytoma of the optic nerve head: a review.

    abstract::The melanocytoma of the optic disc is a deeply-pigmented tumor located on the optic nerve head. In contrast to malignant melanoma, it appears to occur in equal frequency in whites and non-whites. Histologically, it consists of deeply-pigmented plump nervus cells with benign characteristics. No treatment is usually nec...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00133275

    authors: Shields JA

    更新日期:1978-09-01 00:00:00

  • Comparison of inflammatory cytokines levels in the aqueous humor with diabetic retinopathy.

    abstract:PURPOSE:Evidence has accumulated suggesting that various inflammatory cytokines are involved in the progress of diabetic retinopathy (DR), but there are few studies concerning the relationship between individual cytokines levels in the aqueous humor (AH) and the severity of DR. This study aimed to explore the differenc...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01463-9

    authors: Zhang H,Liang L,Huang R,Wu P,He L

    更新日期:2020-10-01 00:00:00

  • Copper foreign body in the lens without damage of iris and lens capsule.

    abstract:PURPOSE:The objective is to report a rare case of asymptomatic penetrating injury with a copper foreign body found during an examination for cataract surgery. METHOD:A case report. RESULTS:A 73-year-old woman had vision loss. Examination by pupil dilation disclosed a dark-brown metallic mass located under the anterio...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-007-9074-5

    authors: Tokoro M,Yasukawa T,Okada M,Ogura Y,Uchida S

    更新日期:2007-10-01 00:00:00

  • Predicting surgical compliance in a cohort of women with trichiasis.

    abstract::Trichiasis/Entropion are the severe consequences of chronic trachoma during early life. Blindness and vision loss is preventable with timely lid surgery to correct trichiasis. In a trachoma hyperendemic region of Central Tanzania, a two year follow-up survey was conducted among 205 women with trichiasis to determine t...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00919249

    authors: West S,Lynch M,Munoz B,Katala S,Tobin S,Mmbaga BB

    更新日期:1994-01-01 00:00:00

  • Anti-tuberculous therapy combined with systemic corticosteroids improves retinal sensitivity in patients with active presumed tuberculous choroiditis.

    abstract::To investigate the efficacy of anti-tuberculous therapy and systemic corticosteroids in patients suffering from active presumed tuberculous choroiditis by the assessment of central retinal sensitivity and fixation characteristics. Six patients (six eyes) with active presumed tuberculous choroiditis were treated with a...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-010-9371-2

    authors: Abu El-Asrar AM,Al-Mezaine HS

    更新日期:2010-10-01 00:00:00

  • Role of brimonidine in the treatment of clinically significant macular edema with ischemic changes in diabetic maculopathy.

    abstract::To evaluate the role of brimonidine (BMD), an alpha-2 agonist, in the management of clinically significant macular edema (CSME) in diabetic maculopathy with ischemic changes. A prospective, randomized controlled trial including 30 eyes of 30 metabolically stable diabetic patients with CSME showing fundus fluorescein a...

    journal_title:International ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10792-013-9871-y

    authors: Gupta PC,Sood S,Narang S,Ichhpujani P

    更新日期:2014-08-01 00:00:00

  • Multimodal imaging patterns of posterior syphilitic uveitis: a review of the literature, laboratory evaluation and treatment.

    abstract:PURPOSE:To review the multimodal imaging patterns of posterior syphilitic uveitis. METHODS:A systematic review. RESULTS:The percentage of syphilis has started to increase again: The World Health Organization has reported 12 million new cases of syphilis each year. In addition, syphilis was responsible for 0.3% of dea...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-020-01285-9

    authors: Pichi F,Neri P

    更新日期:2020-05-01 00:00:00

  • Long-term outcomes of therapeutic penetrating keratoplasty for microbial keratitis in a tertiary care center in Turkey.

    abstract:PURPOSE:To present the long-term results of therapeutic keratoplasty for microbial keratitis in moderate to advanced phases. METHODS:The medical records of 44 patients who underwent therapeutic keratoplasty for microbial keratitis at the ophthalmology clinic of a training and research hospital between June 2012 and Ma...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01538-7

    authors: Kasım B,Koçluk Y

    更新日期:2020-12-01 00:00:00

  • Nontraumatic keratomycosis caused by Alternaria in a glaucoma patient.

    abstract::A case of keratomycosis caused by Alternaria species in a patient with glaucoma is reported. A 55-year-old Japanese man who had been followed for developmental glaucoma presented with corneal ulcer in his right eye, which did not respond to antibacterial agents. There was no history of traumatic episode. Culture on po...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-008-9260-0

    authors: Usui T,Misawa Y,Honda N,Tomidokoro A,Yamagami S,Amano S

    更新日期:2009-12-01 00:00:00

  • Rotational slit-beam marking: an advanced manual corneal astigmatic marking method for toric intraocular lens implantation.

    abstract:PURPOSE:To evaluate the accuracy of an advanced manual corneal astigmatic marking method for toric intraocular lens (IOL) implantation. METHODS:From 52 patients, 52 eyes with cataracts and corneal astigmatism were included. The target axis of the toric IOL was marked with the new manual marking method preoperatively a...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01498-y

    authors: Wu Q,Liu Y,Cai H,Zhang C,Chen X

    更新日期:2020-11-01 00:00:00

  • Strong fixation preference in patients with manifest exotropia: Does it matter or not?

    abstract:PURPOSE:To evaluate the influence of strong fixation preference on clinical and surgical outcomes, in non-amblyopic patients with basic-type intermittent exotropia (IXT). MATERIALS AND METHODS:The records of patients were retrospectively investigated. Non-amblyopic patients with the diagnosis of basic-type IXT were en...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01603-1

    authors: Cakir B,Aksoy NÖ,Bursalı Ö,Özmen S,Çelik E

    更新日期:2020-10-14 00:00:00

  • 'Contact glass for use with high power lasers--geometrical and optical aspects', by P. Roussel and F. Fankhauser (1).

    abstract::Roussel and Fankhauser have proposed contact glasses with a collecting front surface centred on the bundle focus for use with high power lasers. We demonstrate here that the main contribution to the gain in energy density within the focus spot must be attributed to the front surface of the glass. This is at variance w...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00165111

    authors: Lotmar W

    更新日期:1984-06-01 00:00:00

  • Progression of gyrate atrophy measured with ultra-wide-field imaging.

    abstract::The study aims to determine the progression of gyrate atrophy by measuring the area growth of chorioretinal atrophic lesions using ultra-wide-field images (UWFI). A retrospective, observational, and comparative study was conducted and UWFI (200°) were obtained from two patients with gyrate atrophy at baseline and foll...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-015-0085-3

    authors: Salcedo-Villanueva G,Paciuc-Beja M,Villanueva-Mendoza C,Harasawa M,Smith JM,Velez-Montoya R,Olson JL,Oliver SC,Mandava N,Quiroz-Mercado H

    更新日期:2016-02-01 00:00:00

  • Retained lens fragment in the anterior segment as a cause of recurrent anterioruveitis.

    abstract::A 61-year-old male developed recurrent anterior uveitis over a period of 8 months after an uncomplicated phacoemulsification and posterior chamber intraocular lens implantation surgery. This was subsequently found to be due to a retained lens fragment in the anterior segment, with complete resolution following surgica...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-008-9279-2

    authors: Teo L,Chee SP

    更新日期:2010-02-01 00:00:00

  • Graft failure: II. Ocular surface complications.

    abstract::Risk factors for corneal transplantation failure include both immunologic factors, such as graft rejection, corneal neovascularization, and peripheral anterior synechiae, as well as non-immunologic factors, such as ocular surface disorders (OSD) and glaucoma. This review highlights the necessity of having healthy ocul...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-007-9127-9

    authors: Al-Swailem SA

    更新日期:2008-06-01 00:00:00