Abstract：
PURPOSE:To evaluate the cognitive performance of patients with glaucoma and compare it to individuals with Alzheimer's disease (AD). METHODS:This is a prospective, cross-sectional and case-control study. All subjects were assessed using the Mini-Mental State Examination (MMSE) and its subtests verbal fluency, word list memory, delayed recall of the word list, word list recognition test, Boston naming and constructive praxis from Consortium to Establish a Registry for Alzheimer's Disease (CERAD). The results were compared among the groups. RESULTS:A total of 50 healthy elderly with a mean age of 71.2 ± 5.2 years; 41 patients with glaucoma (72.2 ± 4.4 years); and 21 patients with AD (79.0 ± 7.6 years) were included. There was a reduction in all cognitive assessment tests evaluated, both for patients with glaucoma, and for those with AD compared with controls (p < 0.001 for all). Comparing the patients with glaucoma and AD, it was noted that the last had lower cognitive function (p < 0.001), except for the CERAD tests Boston (p = 0.1) and praxis (p = 0.6). Glaucoma patients, however, presented results of cognitive tests similar to those described for patients with mild AD, including lower values for MMSE (21.9 ± 3.7), Boston (10.6 ± 2.6) and praxis (5.9 ± 2.3). CONCLUSION:Glaucoma patients had reduction in cognition when compared to normal individuals. They were similar to the values reported in the literature for patients with mild AD, mostly, and also in some subjects with the presence of advanced AD.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Maurano STP,da Silva DJ,Ávila MP,Magacho Ldoi
10.1007/s10792-017-0658-4subject
Has Abstractpub_date
2018-10-01 00:00:00pages
1839-1844issue
5eissn
0165-5701issn
1573-2630pii
10.1007/s10792-017-0658-4journal_volume
38pub_type
杂志文章abstract：PURPOSE:To analyze the demographic patterns, clinical characteristics, and treatment protocols of optic neuropathies. MATERIALS AND METHODS:The hospital data of patients with optic neuropathy admitted to the Department of Neuro-ophthalmology in a tertiary referral center in Turkey between January 2010 to January 2017 ...
journal_title：International ophthalmology
pub_type： 杂志文章
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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