Abstract：
:In a randomized, double-masked, single drop study the effect of topical isosorbid-mononitrate (ISMO) 0.5% eye drops, the main metabolite of isosorbid-dinitrate, widely used in the treatment of coronary heart diseases, was studied in patients suffering from open angle glaucoma or ocular hypertension. There was no statistically significant IOP change within 8 hours posttreatment after topical administration of ISMO 0.5%. There were no side effects after application of the ophthalmic solution of ISMO 0.5%. There were no significant changes in blood pressure and pulse rate either. A 2% ophthalmic solution of ISMO was investigated with respect to a response on the aqueous humor dynamics in 10 healthy volunteers. Anterior chamber fluorophotometry revealed a mean increase in aqueous flow of 39% within 3 hours after topical application (P less than 0.01). However, in comparison to the placebo treated fellow eyes there were no statistical significant difference in aqueous humor flow during the time of investigation. There was a statistical significant reduction of IOP during the same time period (p less than 0.03) in all treated eyes.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Diestelhorst M,Hinzpeter B,Krieglstein GKdoi
10.1007/BF00171028subject
Has Abstractpub_date
1991-07-01 00:00:00pages
259-62issue
4eissn
0165-5701issn
1573-2630journal_volume
15pub_type
临床试验,杂志文章,随机对照试验abstract：:To determine the optimal area of retinal photocoagulation required for suppressing active neovascularisation (NVI) associated with diabetic retinopathy. We studied 1 eye each of 4 patients in whom active NVI was ophthalmoscopically shown to have been suppressed by additional photocoagulation. These patients initially ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9802-y
更新日期：2014-10-01 00:00:00
abstract：:Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus ...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-008-9223-5
更新日期：2008-06-01 00:00:00
abstract：:To evaluate the potential benefit of intraocular pressure (IOP) reduction in normal-tension glaucoma (NTG) patients in South Korea. A retrospective, multi-center analysis of Korean NTG patients with 5-years follow-up, typical glaucomatous optic disc and/or visual field changes and no recorded IOP >21 mmHg. Progression...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-011-9463-7
更新日期：2011-10-01 00:00:00
abstract：:To study the efficacy and safety of sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft and to investigate the clinical outcomes. Thirty eyes of 30 patients with primary pterygia were treated in this institutional study with excision followed by sutureless amniotic membrane t...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-011-9488-y
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:To compare early optical coherence tomography (OCT) changes in neuroretinal foveal thickness (NFT) after first versus repeated photodynamic treatment (PDT) in eyes with choroidal neovascularization (CNV) due to age-related macular degeneration (AMD). METHODS:This is a prospective comparative case series study....
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9176-0
更新日期：2009-02-01 00:00:00
abstract：:Ewing's sarcoma is a small, blue, round-cell tumor of mesenchymal origin which typically presents itself during the first and the second decades of life. Typically, it is noticed in the long bones of the limbs, pelvis, or ribs. There have been few reports worldwide with none in Pakistan of this rare phenomenon. We rep...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9937-5
更新日期：2014-10-01 00:00:00
abstract：:Clinical trials are often used to evaluate the efficacy of a given treatment. The results of clinical trials however do not always agree with a clinician's experience or intuition. The merits and demerits of Clinical Trials versus Intuition are discussed by using the laser photocoagulation trials of Proliferative Diab...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00159835
更新日期：1986-05-01 00:00:00
abstract：PURPOSE:To report a case of toxic optic neuropathy caused by an ocular bee sting. METHODS:Case report and literature review. RESULTS:A 44-year-old female presented with no light perception vision 2 days after a corneal bee sting in her right eye. She was found to have diffuse cornea edema with overlying epithelial de...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0978-z
更新日期：2019-07-01 00:00:00
abstract：:The choroidal vascular bed has many interesting features such as relatively wide but flat capillaries, fenestrated capillary walls and an enormous blood flow. The high flow rate results in a high oxygen tension in the tissue and is also of importance in the temperature control of the eye. The capillary wall is permeab...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00127638
更新日期：1983-02-01 00:00:00
abstract：:Congenital iris ectropion is an uncommon malformation of the anterior segment of the eye. The authors describe a case of bilateral congenital iris ectropion associated with juvenile glaucoma in an otherwise healthy 9-year-old girl. Intra-ocular pressure (IOP) measured by Goldmann applanation tonometry was 40 mmHg in t...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9388-6
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:To investigate the characteristics of dynamic visual acuity (DVA) and contrast sensitivity (CS) in pseudophakic patients with posterior capsular opacification (PCO). METHODS:Fifty-four eyes (36 patients) with PCO planned for laser capsulotomy were recruited. They underwent examinations of static visual acuity ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01536-9
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To evaluate the accuracy of intraocular lens (IOL) power calculation in relation to optical biometry devices and refraction types. METHODS:Patients undergoing cataract phacoemulsification and insertion of the MX60 IOL were enrolled. Optical biometric measurements were performed with both IOLMaster 700 and Lens...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01355-y
更新日期：2020-07-01 00:00:00
abstract：:To evaluate the efficacy of 25-ga pars plana vitrectomy (PPV) and 25-ga PPV combined with phacoemulsification surgery for managing ciliary block (malignant) glaucoma. The medical records of 11 eyes, in nine consecutive patients with malignant glaucoma were retrospectively reviewed to determine the efficacy of 25-ga PP...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9974-0
更新日期：2015-08-01 00:00:00
abstract：:To report a case of bilateral granulomatous post-streptococcal syndrome uveitis in association with reactive arthritis as manifestation of post-streptococcal syndrome. To our knowledge, this could represent the first reported case in the literature. A 9-year-old girl, with no past ocular history, presented with a 5-da...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9626-1
更新日期：2015-10-01 00:00:00
abstract：:Long-term use of topical drugs can induce changes in the conjunctiva and ocular surface. To determine the conjunctival changes resulting from topical glaucoma medication, patients with glaucoma were selected and classified into seven groups, according to the medication received: 24 eyes were treated with betaxolol, 20...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1005892426045
更新日期：1997-01-01 00:00:00
abstract：:To evaluate the role of brimonidine (BMD), an alpha-2 agonist, in the management of clinically significant macular edema (CSME) in diabetic maculopathy with ischemic changes. A prospective, randomized controlled trial including 30 eyes of 30 metabolically stable diabetic patients with CSME showing fundus fluorescein a...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-013-9871-y
更新日期：2014-08-01 00:00:00
abstract：PURPOSE:Early predictors of diabetic complications may aid in the prevention and/or management of these complications. The aim of this cross-sectional study was to determine the predictive value of retinopathy for the presence of other diabetic complications. METHODS:The population studied comprised 648 patients with ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014409829614
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To evaluate the performance of full-thickness (FT) versus partial-thickness (PT) sutures in a full-thickness corneal wound in an animal model. METHODS:This is a prospective, experimental, comparative, longitudinal study. A 6-mm linear, full-thickness corneal incision was performed on the right eye of eight dom...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01585-0
更新日期：2021-01-01 00:00:00
abstract：:The purpose of this study was to report on the occurrence and management of posterior synechiae (PS) in three hyperopic eyes after iris-fixated anterior chamber phakic IOL implantation. This is a case report of a 55-year-old man and a 55-year-old lady who had undergone iris-fixated anterior chamber phakic IOL implanta...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0202-y
更新日期：2016-12-01 00:00:00
abstract：:The cone dystrophies can be subdivided into 3 functional stages: central cone disease, peripheral cone disease and diffuse cone disease, respectively. In the patient material of our clinic the sex distribution of patients presenting with te diffuse cone disease stage was abnormal: 22 males and 3 females. The authors s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00155631
更新日期：1987-08-01 00:00:00
abstract：:The retinal toxicity of vancomycin in infusion solution used in vitrectomy and lensectomy was investigated in rabbit eyes by means of electroretinography and histologic study (light microscopy). Concentrations of 8 micrograms/ml, 16 micrograms/ml, and 32 micrograms/ml of vancomycin in balanced salt solution caused no ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00942780
更新日期：1993-04-01 00:00:00
abstract：PURPOSE:To compare sub-tenon steroid plus anti-VEGF injection with anti-VEGF injection solely in the treatment of resistant diabetic macular edema (DME). METHOD:Patients who exhibited insufficient anatomic [over 350 μm central macular thickness (CMT)] and less than 3 lines of visual gain at least six anti-VEGF injecti...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-018-0977-0
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:Traditional color vision tests depend on subjective judgments and are not suitable for infant children and subjects with cognitive dysfunction. We aimed to explore an objective and quantitative color vision testing method based on sweep steady-state visual evoked potentials (sweep SSVEPs) and compare the result...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01613-z
更新日期：2020-10-12 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and safety of the bilateral simultaneous XEN (BISIXEN) surgery in open-angle glaucoma patients. METHODS:Retrospective analysis of a prospective data base conducted on uncontrolled glaucoma patients who underwent BISIXEN surgery. Primary endpoint measure was the incidence of sight-thr...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01640-w
更新日期：2021-01-02 00:00:00
abstract：PURPOSE:To explore whether retrobulbar administration of nerve growth factor (NGF) can restore visual function of streptozotocin-induced diabetes rats. METHODS:A high-sucrose/high-fat diet and single injection of streptozotocin (STZ) were used in modeling diabetes. During week 13-15 after STZ injection, diabetic rats ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01537-8
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:With the increasing prevalence of electronic readers (e-readers) for vocational and professional uses, it is important to discover if there are visual consequences in the use of these products. There are no studies in the literature quantifying the incidence or severity of eyestrain, nor are there clinical c...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-016-0281-9
更新日期：2017-04-01 00:00:00
abstract：:Onchocerciasis is a devastating blinding disease caused by the parasite Onchocerca volvulus that infects about 80 million people, causing blindness and visual impairment in 1-2 million people. In hyperendemic areas, more than half of the population will become blind from onchocerciasis before they die. Blindness is th...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00158317
更新日期：1990-05-01 00:00:00
abstract：:To report a unusual case of an isolated traumatic stellated tarso-conjunctival laceration located in the upper left eyelid without eyelid margin involvement and with normal ocular examination. A 19 year-old male wounded by a bokken (wooden katana) while practicing a sham duel had an isolated eyelid tarso-conjunctival ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9573-x
更新日期：2012-08-01 00:00:00
abstract：:To look for a correlation between or the effect of anisometropia amblyopia on retrobulbar blood flow parameters. Peak systolic velocity (PSV) and end-diastolic velocity (EDV) of the ophthalmic artery (OA), central retinal artery (CRA), and temporal posterior ciliary artery (tPCA) were measured with color Doppler imagi...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9572-y
更新日期：2012-08-01 00:00:00
abstract：:Diabetes mellitus and pregnancy have reciprocal influences between them, therefore diabetes mellitus may complicate the course of pregnancy as well as pregnancy can worsen the performance of diabetes especially at the fundus oculi. Several factors seem to play a role in retinal neovascularization. Actually it's not po...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9906-z
更新日期：2014-08-01 00:00:00
