Abstract：
:Onchocerciasis is a devastating blinding disease caused by the parasite Onchocerca volvulus that infects about 80 million people, causing blindness and visual impairment in 1-2 million people. In hyperendemic areas, more than half of the population will become blind from onchocerciasis before they die. Blindness is the most important effect of the disease and results, in part, from direct invasion of the eye by microfilariae. The recent development of ivermectin has revolutionized our ability to treat this disease. An annual oral dose of only 150 mg/kg completely suppresses the disease manifestations. Programs for the community-based mass distribution of ivermectin are now being conducted and promise to control this major blinding scourge.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Taylor HRdoi
10.1007/BF00158317subject
Has Abstractpub_date
1990-05-01 00:00:00pages
189-94issue
3eissn
0165-5701issn
1573-2630journal_volume
14pub_type
杂志文章,评审abstract：PURPOSE:Corneal melting with perforation is a severe ophthalmic complication of autoimmune disorders such as rheumatoid arthritis. It requires urgent medical management in order to maintain the integrity of the globe and preserve vision. Treating this complication by penetrating keratoplasty is problematic due to the h...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0545-z
更新日期：2018-06-01 00:00:00
abstract：:To evaluate efficacy and safety of same site re-operation in eyes with failed trabeculectomy. A retrospective, noncomparative, interventional case series. We reviewed the medical records of 35 eyes of 35 patients who underwent same-site re-operation for failed trabeculectomy. The surgery involved a fornix-based perito...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9840-5
更新日期：2014-06-01 00:00:00
abstract：:A 71-year-old man presented with a large disciform scar in the right eye and hard (nodular) as well as soft (granular) drusen scattered throughout the posterior pole of the left eye. A large serous pigment epithelial detachment was evident in the drusen area of the left fundus. Six months later a tear of the retinal p...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00139344
更新日期：1987-06-01 00:00:00
abstract：PURPOSE:To report a case of bilateral Terson Syndrome with sub inner limiting membrane hemorrhage associated with a rare finding: perimacular fold. METHODS:The patient, a 34 years old female with aneurysmal subarachnoid hemorrhage and bilateral Terson syndrome was admitted to the Ophthalmology department, complaining ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0822-5
更新日期：2019-02-01 00:00:00
abstract：:In order to evaluate possible etiological factors and the natural course of 'idiopathic' preretinal fibrosis in young persons, nine consecutive patients with macular pucker diagnosed under the age of 50 years were examined. There were six women and three men with the mean age of 27.2 years (range 15-50) and the mean f...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00202776
更新日期：1987-02-01 00:00:00
abstract：:This study aimed to present precancerous and cancerous epithelial eyelid lesions, their histopathological features, and possible correlations with clinical parameters. The retrospective study included 147 formalin-fixed, paraffin-embedded samples. We studied precancerous and cancerous epithelial eyelid lesions. Preneo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0258-8
更新日期：2017-02-01 00:00:00
abstract：UNLABELLED:The purpose of this study is to evaluate the effect of trephination with free scleral auto-implant plug exposed to Mitomycin-C out of the eye, in surgical treatment of primary open-angle glaucoma (POAG), in comparison with efficacy of trabeculectomy with MMC (32 eyes with POAG of patients, younger than 55 ye...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00212952
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To assess posterior inflammation using a fluorescein (FA)/indocyanine-green angiography (ICGA) scoring system, and compare them to the presently recommended outcome measure, the standardization of uveitis nomenclature vitreous haze score (SUN-VH) in stromal choroiditis. METHODS:This was a retrospective study o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0979-y
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:To report a technique of intra-scleral fixation of the iris hooks for trans-scleral capsular bag fixation in patient with zonular dialysis. METHODS:Two scleral flaps, two scleral tunnels and two sclerotomies were formed. The anterior capsule was captured and pulled by the iris hooks resulting in the IOL adopti...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0623-2
更新日期：2018-08-01 00:00:00
abstract：PURPOSE:To assess the level of awareness among UK ophthalmic surgeons of the potential risks from starch powdered surgical gloves during ophthalmic surgery and to show by electron microscopy that starch granule contamination can occur during ophthalmic surgery. SETTING:A sample (N = 46) of UK ophthalmologists from the...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006392915801
更新日期：1998-01-01 00:00:00
abstract：:The appearance of a hypopyon is an extremely uncommon finding in acute angle-closure glaucoma and only a few cases have been previously reported in the literature. We report a fifty-year-old female who, following a recent bereavement, presented with classical features of acute angle-closure glaucoma and a hypopyon. Th...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00942925
更新日期：1993-06-01 00:00:00
abstract：:Lipoid proteinosis is a rare disorder involving multiple organ systems. The ocular manifestations are usually trivial, but greatly aid in the diagnosis. We describe a patient who presented to us with typical moniliform blepharosis. A brief description of relevance to the ophthalmologist and review of the literature fo...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-011-9417-0
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:To investigate the feasibility of intrastromal lenticule insertion to restore corneal shape in a model of ectatic human cornea. METHODS:For this experimental ex vivo study on 34 human corneas unsuitable for transplantation, 17 corneas were thinned by decentralized posterior excimer laser ablation to 200 μm thi...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01106-8
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND/AIMS:To study the observer-related variability of optic nerve head (ONH) measurements using confocal laser scanning tomography (HRT I) in a screening setting. METHODS:Six experienced glaucoma specialists independently evaluated 50 ONH topographies from 25 adults using HRT software ver. 2.01 in a masked fash...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-006-9022-9
更新日期：2005-08-01 00:00:00
abstract：:The aim of this study is to determine the incidence of cystoid macular edema (CME) following repositioning and McCannel iris-suturing of dislocated intraocular lenses. This study is conducted in an urban private practice. A retrospective chart review was performed on consecutive patients who presented with posteriorly...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9964-2
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PE...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0498-2
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Bevacizumab (Avastin) has been used as off-label treatment for the specific inhibition of the vascular endothelial growth factor (VEGF). Although only intravenous administration of the drug is approved in combination therapy of colorectal carcinoma, promising short-term results have been reported about its i...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9122-1
更新日期：2008-04-01 00:00:00
abstract：PURPOSE:To describe the intraoperative complications and the learning curve of microincision cataract surgery assisted by femtosecond laser (FLACS) with bimanual technique performed by an experienced surgeon. METHODS:It is a prospective, observational, comparative case series. A total of 120 eyes which underwent biman...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0776-z
更新日期：2019-01-01 00:00:00
abstract：:Acute and invasive fungal infections are usually seen in immunocompromised and debilitated patients. We report a young immunocompetent 28-year-old Indian male who presented with unilateral endogenous endophthalmitis in the left eye and was managed with pars plana vitreous surgery. The polymerase chain reaction from th...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9235-1
更新日期：2009-08-01 00:00:00
abstract：PURPOSE:We sought to assess the risk factors associated with avascular fibrous membrane development in patients with retinopathy of prematurity (ROP). METHODS:This retrospective, cross-sectional study included premature infants diagnosed with ROP. Gestational age, birth weight, stage and zone of the ROP, the presence ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01484-4
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:Aromatase inhibitors (anastrozole, letrozole) and selective estrogen receptor modulators (tamoxifen) are widely used as adjuvant hormonal therapy in women with hormone receptor-positive breast cancer. We aimed to evaluate the effects of oral adjuvant hormonotherapy on tear functions in patients with breast canc...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01384-7
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:To investigate the changes in the anterior chamber volume (ACV) with swept-source optical coherence tomography (SS-OCT) after cataract surgery and the factors that influence these ACV changes. METHODS:This was a prospective cohort study. Fifty-one patients who underwent cataract surgery were enrolled. Their AC...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1012-1
更新日期：2019-08-01 00:00:00
abstract：:Congenital iris ectropion is an uncommon malformation of the anterior segment of the eye. The authors describe a case of bilateral congenital iris ectropion associated with juvenile glaucoma in an otherwise healthy 9-year-old girl. Intra-ocular pressure (IOP) measured by Goldmann applanation tonometry was 40 mmHg in t...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9388-6
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:To investigate the changes in ocular higher-order aberrations (HOA) after trabeculectomy using mitomycin-C (MMC). METHODS:We retrospectively reviewed data for 63 eyes from 63 glaucoma patients who had undergone MMC augmented trabeculectomy. We measured intraocular pressure (IOP), refractive errors, anterior ch...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0802-1
更新日期：2019-01-01 00:00:00
abstract：INTRODUCTION:We report on a 62-year-old healthy woman who suffered from bilateral predescemetic opacities, where the underlying disorder could not be identified. She had bilateral keratopathy with corneal edema, a diffuse predescemetic avascular haze and deszemetic folds. Because of high hyperopia (right +7.50/left +7....
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/b:inte.0000018521.88103.17
更新日期：2004-01-01 00:00:00
abstract：PURPOSE:To investigate complex and different phenotypes in seven Chinese patients diagnosed with Bardet-Biedl syndrome (BBS) and carrying pathogenic mutations. METHODS:Seven unrelated BBS patients were enrolled. Their medical and ophthalmic histories were reviewed, and comprehensive clinical examinations, such as fund...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01415-3
更新日期：2020-09-01 00:00:00
abstract：:After glaucoma filtering surgery subconjunctival injection of human recombinant tissue plasminogen activator may promote the function of glaucoma filter bleb and increase outflow facility. It can also increase postoperative complications, such as corneal damage. The aim of our research was to determine corneal endothe...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00156413
更新日期：1995-01-01 00:00:00
abstract：PURPOSE:To investigate the diurnal fluctuations of macular vessel density (VD) in primary open-angle glaucoma (POAG) and healthy subjects using optical coherence tomography angiography. METHODS:A total of 22 POAG eyes and 15 healthy eyes were included in this study. Macular VD, intraocular pressure, and blood pressure...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01408-2
更新日期：2020-09-01 00:00:00
abstract：:The Hermansky-Pudlak Syndrome, a "tyrosinase positive' form of oculocutaneous albinism, is a triad comprising albinism, a hemorrhagic diathesis and ceroid-lipofuscin storage. A pedigree is presented showing consanguinity with a pattern of pseudodominance. Electroretinography in two isolated Hermansky-Pudlak subjects w...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00139585
更新日期：1981-08-01 00:00:00
abstract：:To determine the optimal area of retinal photocoagulation required for suppressing active neovascularisation (NVI) associated with diabetic retinopathy. We studied 1 eye each of 4 patients in whom active NVI was ophthalmoscopically shown to have been suppressed by additional photocoagulation. These patients initially ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9802-y
更新日期：2014-10-01 00:00:00
