Abstract:
PURPOSE:We sought to assess the risk factors associated with avascular fibrous membrane development in patients with retinopathy of prematurity (ROP). METHODS:This retrospective, cross-sectional study included premature infants diagnosed with ROP. Gestational age, birth weight, stage and zone of the ROP, the presence of plus disease, and laser photocoagulation (LP) application were noted for each patient. Location, extension, development time, vanishing time of the avascular fibrous membrane, and associated complications were also noted. Patients who developed avascular fibrous membrane formed the membrane group (n = 38) and those who did not develop avascular fibrous membrane formed the control group (n = 208). RESULTS:Mean gestational age and birth weight did not differ between the groups (p = 0.897 and p = 0.343). ROP developed significantly earlier in the control group than in the membrane group (p < 0.001). The patients in the control group underwent LP treatment significantly earlier than did patients in the membrane group (p < 0.001). Regression analysis showed that higher postmenstrual age at the time of ROP diagnosis increased the risk of avascular fibrous membrane development by up to 1.6-fold (p = 0.002; 95% CI 1.2-2.3) and later LP treatment was associated with a 3.3-fold increased risk of avascular fibrous membrane development (p = 0.003; 95% CI 1.5-7.3). CONCLUSIONS:Late-onset ROP and later LP treatment were found to be associated with an increased risk of avascular fibrous membrane development in patients with ROP.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Kabatas EU,Ozates Sdoi
10.1007/s10792-020-01484-4subject
Has Abstractpub_date
2020-11-01 00:00:00pages
3005-3011issue
11eissn
0165-5701issn
1573-2630pii
10.1007/s10792-020-01484-4journal_volume
40pub_type
杂志文章abstract:INTRODUCTION:Uveitis encompasses a wide variety of sight-threatening diseases characterized by intraocular inflammation. It is often classified as infectious and non-infectious uveitis. Unlike infectious uveitis, a distinct infectious agent cannot be identified in non-infectious uveitis and disease origin is usually au...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
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journal_title:International ophthalmology
pub_type: 杂志文章
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更新日期:2013-06-01 00:00:00
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journal_title:International ophthalmology
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journal_title:International ophthalmology
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journal_title:International ophthalmology
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abstract::Knowledge of the presentation pattern of glaucoma helps in providing more understanding of the disease, leading to better control. The aim of this study was to determine the presentation pattern among newly diagnosed glaucoma patients in Lagos, Nigeria. This was a multicenter cross-sectional survey of newly diagnosed ...
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更新日期:2017-08-01 00:00:00
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pub_type: 杂志文章
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journal_title:International ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2020-11-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
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更新日期:1981-08-01 00:00:00
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更新日期:2020-06-01 00:00:00
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journal_title:International ophthalmology
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journal_title:International ophthalmology
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journal_title:International ophthalmology
pub_type: 杂志文章,评审
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更新日期:2014-08-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/b:inte.0000006784.52885.e9
更新日期:2001-01-01 00:00:00