Abstract:
PURPOSE:To report a case of retinal pigment epithelial tear following intravitreal ranibizumab injection for subfoveal choroidal neovascularization. METHODS:Retrospective single case review. RESULTS:A 78-year-old Caucasian female was treated with intravitreal ranibizumab for occult subfoveal choroidal neovascularization (CNV) from age-related macular degeneration (AMD). She returned for evaluation with decreased vision and was found to have a retinal pigment epithelial tear on biomicroscopy. Fluorescein angiography and OCT testing confirmed the clinical findings. CONCLUSION:Although a pigment epithelial tear in neovascular AMD can represent natural history, prior reports of such tears after thermal laser, photodynamic therapy with verteporfin and following intravitreal injection of pegaptanib Na combined with this case report suggest that clinicians should be aware of and monitor patients for the possibility of this complication after intravitreal injections of ranibizumab.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Apte RSdoi
10.1007/s10792-007-9066-5subject
Has Abstractpub_date
2007-02-01 00:00:00pages
59-61issue
1eissn
0165-5701issn
1573-2630journal_volume
27pub_type
杂志文章abstract:OBJECTIVE:To observe the effect of sirt1 on retinal ganglion cells (RGC) with high glucose culture and to explore the role of sirt1 in the development of diabetic retinopathy. Method RGC was infected by sirt1 lentivirus overexpression vector pLV5-sirt1 and interference vector pLV3-si-sirt1. The normal control group and...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01638-4
更新日期:2020-11-11 00:00:00
abstract::Preliminary results of a larger investigation on correlation between Retinal Nerve Fiber Layer Defects (RNFL) and Automated Perimetry (AP) are presented. A group of ocular hypertensive patients was recruited and a cross-section, randomized study was carried out. The group was composed of 54 eyes from 28 patients; 15 m...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00917968
更新日期:1992-09-01 00:00:00
abstract::The Hermansky-Pudlak Syndrome, a "tyrosinase positive' form of oculocutaneous albinism, is a triad comprising albinism, a hemorrhagic diathesis and ceroid-lipofuscin storage. A pedigree is presented showing consanguinity with a pattern of pseudodominance. Electroretinography in two isolated Hermansky-Pudlak subjects w...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00139585
更新日期:1981-08-01 00:00:00
abstract:PURPOSE:To elucidate the role of trabeculectomy in advanced glaucoma. MATERIALS AND METHODS:Only patients with primary open-angle glaucoma were selected. All patients who had cup-disc ratio of 0.9 or a near-total cupping were given a trial of aggressive maximum medical therapy for IOP control for at least 4 weeks. Tar...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0797-7
更新日期:2019-01-01 00:00:00
abstract::To report a case of bilateral granulomatous post-streptococcal syndrome uveitis in association with reactive arthritis as manifestation of post-streptococcal syndrome. To our knowledge, this could represent the first reported case in the literature. A 9-year-old girl, with no past ocular history, presented with a 5-da...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9626-1
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:State Gentamicin antibiotic prophylaxis is contraindicated in 25 gauge Transconjunctival Sutureless Vitrectomy. METHODS:A 75-year-old diabetic woman was affected by glaucoma and mild diabetic retinopathy in both eyes, and epiretinal membrane in the left eye. A 25-gauge Transconjunctival Sutureless Vitrectomy (...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9148-4
更新日期:2008-10-01 00:00:00
abstract:PURPOSE:To investigate the characteristics of dynamic visual acuity (DVA) and contrast sensitivity (CS) in pseudophakic patients with posterior capsular opacification (PCO). METHODS:Fifty-four eyes (36 patients) with PCO planned for laser capsulotomy were recruited. They underwent examinations of static visual acuity ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01536-9
更新日期:2020-12-01 00:00:00
abstract::In a prospective study of untreated ocular hypertension 117 eyes were non-exfoliative and 20 eyes exfoliative. The percentage of optic disc pallor was significantly larger in the exfoliative than in the non-exfoliative group, whereas no significant differences were found in IOP or in the visual field. ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF02028632
更新日期:1989-01-01 00:00:00
abstract::To report a unusual case of an isolated traumatic stellated tarso-conjunctival laceration located in the upper left eyelid without eyelid margin involvement and with normal ocular examination. A 19 year-old male wounded by a bokken (wooden katana) while practicing a sham duel had an isolated eyelid tarso-conjunctival ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9573-x
更新日期:2012-08-01 00:00:00
abstract::Thirty strains of Staphylococcus epidermidis, ten each from normal conjunctival sacs, corneal ulcer cases and from those who developed postoperative endophthalmitis, were examined for their dermonecrotic and haemolytic activities. Dermonecrosis was studied on rabbit skin whereas haemolysis was determined against sheep...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00149145
更新日期:1982-11-01 00:00:00
abstract::The purpose of this study was to evaluate the effect of Nd.YAG-laser treatment on retinal function. All the patients treated showed a temporary decrease of visual acuity immediately after treatment. The ERG and EOG recordings were identical before and after treatment. The Umazume-Ohta test showed temporary central or ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF02027893
更新日期:1987-10-01 00:00:00
abstract:PURPOSE:To investigate the natural course, visual outcome, and risk factors for visual loss after nonarteritic anterior ischemic optic neuropathy (NAION) attack in Chinese patients from a tertiary medical center in Southern Taiwan. METHODS:This is a longitudinal observational study that included sixty NAION patients, ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01448-8
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To report the first European case of endogenous endophthalmitis secondary to a liver abscess due to Klebsiella pneumoniae expressing MagA gene. METHODS:A 33-year-old diabetic patient was admitted for fever and right upper quadrant abdominal pain. Abdominal computed tomography and laboratory studies were perfor...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9111-4
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:Recently, the vasodilator relaxin 2 has been introduced as a treatment for acute heart failure. However, its role on vessels of the eye and intraocular pressure (IOP) remains unclear though it has been hypothesized to induce a decrease IOP after intramuscular injection in humans. We aimed to test whether the ho...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0884-4
更新日期:2019-04-01 00:00:00
abstract::The aim of this study was to evaluate tear osmolarity and ocular comfort with two different types of hydrogel daily disposable lenses. The right eyes of 15 first-time contact lens users were included in this prospective study. All eyes wore hilafilcon B silicone hydrogel contact lenses for 8 h (group 1). After 1 week ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9556-y
更新日期:2012-06-01 00:00:00
abstract::IgG4-related disease is a recently defined inflammatory process characterized by IgG4-bearing plasma cells in the involved tissues. The most common sites of involvement are the pancreas, hepatobiliary tract, salivary glands, lymph nodes, retroperitoneum and orbit, especially the lacrimal glands. Other ocular or ocular...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-015-0070-x
更新日期:2015-08-01 00:00:00
abstract::To describe a congenital retinal macrovessel with macular thickening. This case was investigated using fundus photography, fluorescein angiography, Spectralis optical coherence tomography and a 10-2 visual field test. A 23-year-old man was referred to our clinic with decreased vision in the right eye. Fundus examinati...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-010-9402-z
更新日期:2011-02-01 00:00:00
abstract::Out of 49 patients diagnosed as having Stargardt's disease that have been clinically reviewed, 22 of these cases have been followed for a period up to 13 years. The cases have been studied in three subgroups, according to their fundus appearance. Patients from group I were those whose lesions were confined to the macu...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00137651
更新日期:1985-11-01 00:00:00
abstract::Traumatic expulsive iridodialysis is a rare complication after trauma by a blunt object in eyes with previous small-incision cataract surgery. The presence of an intact lens capsule with an intraocular lens was thought to protect against damage beyond the posterior capsule. We report a case of dehiscence of the catara...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-011-9491-3
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To gain an insight into the manufacturing and fitting of artificial eyes in children and potential improvements to the process. METHOD:An online qualitative survey was distributed to 39 ocularists/prosthetists in Europe and Canada. Participants were recruited through purposive sampling, specifically maximum va...
journal_title:International ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10792-016-0383-4
更新日期:2017-10-01 00:00:00
abstract::To determine the optimal area of retinal photocoagulation required for suppressing active neovascularisation (NVI) associated with diabetic retinopathy. We studied 1 eye each of 4 patients in whom active NVI was ophthalmoscopically shown to have been suppressed by additional photocoagulation. These patients initially ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9802-y
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:To report a case of Pseudomonas aeruginosa endophthalmitis with choroidal abscess formation in a patient with bronchiectasis. METHODS:Case report. RESULTS:A 75-year-old gentleman with bronchiectasis and P. aeruginosa pneumonia developed painless loss of right eye vision. The patient had previously undergone b...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9126-x
更新日期:2008-08-01 00:00:00
abstract::We compared uveitis patients who attended a general eye clinic (n = 183) with those who attended the ophthalmology department of a university hospital (n = 550) to examine factors that affect the clinical statistics of uveitis outpatients. We observed that diabetic iritis and herpetic iritis were significantly more fr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-009-9336-5
更新日期:2010-06-01 00:00:00
abstract::Ewing's sarcoma is a small, blue, round-cell tumor of mesenchymal origin which typically presents itself during the first and the second decades of life. Typically, it is noticed in the long bones of the limbs, pelvis, or ribs. There have been few reports worldwide with none in Pakistan of this rare phenomenon. We rep...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-014-9937-5
更新日期:2014-10-01 00:00:00
abstract::The effect of therapeutic ultrasound for the treatment of refractory glaucoma was evaluated in 44 patients by comparing average IOP curves measured before and 3-4 months after treatment. The insonification regime was standardized and the glaucoma medication in each individual patient was unchanged during IOP curve mea...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00918000
更新日期:1992-09-01 00:00:00
abstract::To investigate the correlation between the perifoveal capillary blood flow velocity (BFV) and the vitreous level of pigment epithelium-derived factor (PEDF) in patients with branch retinal vein occlusion (BRVO) and macular edema. In a retrospective interventional study of patients with BRVO and macular edema, undilute...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9584-7
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To report a childhood case of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) carrying the R92Q variant with a vision-threatening bilateral panuveitis. METHODS:Case report and review of the literature. RESULTS:A 7-year-old boy presented with an active bilateral panuveitis and a macular ras...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-017-0785-y
更新日期:2019-01-01 00:00:00
abstract::A 61-year-old male developed recurrent anterior uveitis over a period of 8 months after an uncomplicated phacoemulsification and posterior chamber intraocular lens implantation surgery. This was subsequently found to be due to a retained lens fragment in the anterior segment, with complete resolution following surgica...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9279-2
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of the bilateral simultaneous XEN (BISIXEN) surgery in open-angle glaucoma patients. METHODS:Retrospective analysis of a prospective data base conducted on uncontrolled glaucoma patients who underwent BISIXEN surgery. Primary endpoint measure was the incidence of sight-thr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01640-w
更新日期:2021-01-02 00:00:00
abstract:PURPOSE:To investigate the effects of glaucomatous damage on the mfVEP parameters of patients suffering from primary open-angle glaucoma (POAG). METHODS:Fifteen healthy subjects and 15 patients with unilateral POAG participated in this study. In addition, routine ophthalmological examinations including visual acuity, ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01138-0
更新日期:2019-12-01 00:00:00