Abstract:
:To investigate the correlation between the perifoveal capillary blood flow velocity (BFV) and the vitreous level of pigment epithelium-derived factor (PEDF) in patients with branch retinal vein occlusion (BRVO) and macular edema. In a retrospective interventional study of patients with BRVO and macular edema, undiluted vitreous specimens were obtained from 12 eyes of 12 patients. The level of PEDF was then measured in vitreous samples by an enzyme-linked immunosorbent assay. Before vitreous fluid sampling, perifoveal capillary BFV was measured by fluorescein angiography with a scanning laser ophthalmoscope and the tracing method. Subsequently, the relationship between perifoveal capillary BFV and the vitreous level of PEDF was investigated. There was a significant positive correlation between BFV and the vitreous level of PEDF in the 12 patients (ρ = 0.75, p = 0.013). The vitreous level of PEDF may influence macular microcirculation in patients with BRVO and macular edema.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Noma H,Funatsu H,Mimura Tdoi
10.1007/s10792-012-9584-7subject
Has Abstractpub_date
2012-10-01 00:00:00pages
485-9issue
5eissn
0165-5701issn
1573-2630journal_volume
32pub_type
杂志文章abstract:PURPOSE:Growth factors are considered as key molecules that participating in fibrosis formation. This research aimed to clarify potential effects of p53 on regulation of transforming growth factor β (TGF-β) and fibrosis formation and investigate the associated mechanisms. METHODS:Vimentin was examined to identify huma...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01320-9
更新日期:2020-06-01 00:00:00
abstract::The purpose of this study was to evaluate the effect of Nd.YAG-laser treatment on retinal function. All the patients treated showed a temporary decrease of visual acuity immediately after treatment. The ERG and EOG recordings were identical before and after treatment. The Umazume-Ohta test showed temporary central or ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF02027893
更新日期:1987-10-01 00:00:00
abstract::To evaluate the efficacy of 25-ga pars plana vitrectomy (PPV) and 25-ga PPV combined with phacoemulsification surgery for managing ciliary block (malignant) glaucoma. The medical records of 11 eyes, in nine consecutive patients with malignant glaucoma were retrospectively reviewed to determine the efficacy of 25-ga PP...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-014-9974-0
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:The purpose was to evaluate the angle of the anterior chamber (ACA) and intraocular pressure (IOP) changes following eventless phacoemulsification surgery done for non-glaucomatous Egyptian patients. METHODS:A prospective, interventional study involved 126 cataractous patients undergoing phacoemulsification wi...
journal_title:International ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10792-019-01234-1
更新日期:2020-03-01 00:00:00
abstract::The effect of therapeutic ultrasound for the treatment of refractory glaucoma was evaluated in 44 patients by comparing average IOP curves measured before and 3-4 months after treatment. The insonification regime was standardized and the glaucoma medication in each individual patient was unchanged during IOP curve mea...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00918000
更新日期:1992-09-01 00:00:00
abstract:PURPOSE:To compare corneal graft survival rates after penetrating keratoplasty (PK) and Descemet's stripping endothelial keratoplasty (DSEK) in patients with a glaucoma drainage device (GDD) or medically managed glaucoma. METHODS:A retrospective chart review was conducted on consecutive patients who underwent primary ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0451-4
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To describe indocyanine green angiography (ICGA) and visual acuity (VA) results in patients with neovascular age-related macular degeneration (nAMD) refractory to ranibizumab switched to aflibercept. METHODS:This study is a prospective interventional case series. Thirty-two eyes of 32 patients with nAMD showin...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01082-z
更新日期:2019-11-01 00:00:00
abstract::This paper builds on results of a previous paper on the prevalence of trachomatous visual impairment as the foundation for assessing the global burden of trachomatous blindness and low vision: approximately 2.9 million cases of trachomatous blindness and 3.8 million low visioned corresponding to a global prevalence of...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00130921
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To perform vector analysis of changes in corneal astigmatism and evaluate changes in corneal topographic parameters following the lateral tarsal strip (LTS) procedure in patients with involutional ectropion or entropion. METHODS:Nineteen eyes of 15 patients (10 eyes with ectropion and 9 eyes with entropion) we...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0987-y
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:To report a case of resolution of retinal arterial aneurysms in a patient of idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) treated with oral steroids. METHODS:This study contains case report and review of literature. RESULTS:A 16-year-old girl with stage 2 IRVAN was treated with oral ste...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-018-0913-3
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:To identify baseline optical coherence tomography (OCT) factors in ischemic central retinal vein occlusion (CRVO) that predict response to bevacizumab injections. METHODS:Patients underwent OCT at diagnosis and the central macular thickness, subretinal fluid width and height as well as the presence of intraret...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01604-0
更新日期:2020-10-22 00:00:00
abstract:BACKGROUND:The surgical management of macular holes has been a subject of controversy in recent years. Various techniques such as vitrectomy, membrane peeling, and gas tamponade with or without transforming growth factor-beta 2, and recently the use of autologous platelets have produced closure rates from 58% to 96%, d...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1023/a:1005866002930
更新日期:1997-01-01 00:00:00
abstract::The clinical and histopathological findings are described in a case of cerebral and ocular abnormalities associated with (congenital) muscular dystrophy. Histopathological examination of the eyes revealed a fetal configuration of the anterior chamber angle, elongated ciliary processes, cataract, persistence of primary...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF01007744
更新日期:1993-08-01 00:00:00
abstract::The beneficial effect of photocoagulation in diabetic retinopathy is now established (2-6, 10). Whereas the capability of providing photocoagulation is widespread, the indications and actual techniques are poorly defined. In this paper, we propose to discuss the principles of photocoagulation. In a following paper the...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00133274
更新日期:1978-09-01 00:00:00
abstract::The purpose of this study was to report on two novel missense mutations of the cornea-specific TGFBI gene in one single patient and in two generations of a family diagnosed with unique corneal dystrophy (CD) phenotypes. Ophthalmologic examination, in several cases ocular coherence tomography of the anterior segment (A...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0216-5
更新日期:2016-12-01 00:00:00
abstract::To describe the epidemiology, mechanism of injury, and final visual and anatomical outcomes of pediatric patients with open globe injury. The medical records of patients aged ≤ 16 years diagnosed with open globe injury between January 2006 and December 2010 were retrospectively reviewed. Forty-nine pediatric patients ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9890-8
更新日期:2014-08-01 00:00:00
abstract:PURPOSES:This research aimed to investigate effects and risk factors on non-contact tonometer (NCT) readings in healthy myopic subjects by employing cross-sectional study design. METHODS:Totally, sixty otherwise healthy myopic volunteers (mean 28.4 years old) with 90% female were recruited in ophthalmic clinic. The ro...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01203-8
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:The purpose of this article was to introduce a novel surgical technique for the management of peripheral Descemet's membrane perforation during deep anterior lamellar keratoplasty (DALK). METHODS:First, a thin stromal patch was prepared either from the anterior stromal lamella cut during DALK or from the anter...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-01065-6
更新日期:2019-10-01 00:00:00
abstract::Central serous chorioretinopathy (CSCR) is characterized by neurosensory retinal detachment. Because the retina pigment epithelium and choroidal pathology is the current mechanism in CSCR, many studies in the literature focused on the outer retinal layers. There is little information about the functional or histologic...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0278-4
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To observe the effect of sirt1 on retinal ganglion cells (RGC) with high glucose culture and to explore the role of sirt1 in the development of diabetic retinopathy. Method RGC was infected by sirt1 lentivirus overexpression vector pLV5-sirt1 and interference vector pLV3-si-sirt1. The normal control group and...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01638-4
更新日期:2020-11-11 00:00:00
abstract::The glistening and delayed opacification of intraocular lenses (IOLs) has been reported in literature as a late and permanent change in the acrylic IOL due to temperature change. We report a case in which clouding and opacification of an IOL occurred intraoperatively within a few seconds of implantation into the capsu...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-011-9481-5
更新日期:2011-12-01 00:00:00
abstract::A 71-year-old man presented with a large disciform scar in the right eye and hard (nodular) as well as soft (granular) drusen scattered throughout the posterior pole of the left eye. A large serous pigment epithelial detachment was evident in the drusen area of the left fundus. Six months later a tear of the retinal p...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00139344
更新日期:1987-06-01 00:00:00
abstract:INTRODUCTION:We report on a 62-year-old healthy woman who suffered from bilateral predescemetic opacities, where the underlying disorder could not be identified. She had bilateral keratopathy with corneal edema, a diffuse predescemetic avascular haze and deszemetic folds. Because of high hyperopia (right +7.50/left +7....
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/b:inte.0000018521.88103.17
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Rhegmatogenous retinal detachment associated with choroidal detachment (RRDCD) refers to the detachment of the ciliary body and choroid from the sclera along with retinal detachment. The recovery of visual function is often far worse after surgical treatment of RRDCD than following anatomical reduction for c...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01433-1
更新日期:2020-10-01 00:00:00
abstract::Most of the tissue used for penetrating keratoplasty is issued through eye banks that store the corneoscleral button either in hypothermic storage at 2-6 degrees C or in organ culture at 31-37 degrees C. These two preservation techniques differ in technical aspects, tissue evaluation possibilities, storage time and mi...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-007-9086-1
更新日期:2008-06-01 00:00:00
abstract::Various techniques which use monoclonal antibodies to detect Chlamydia trachomatis in clinical specimens are reviewed. An investigation comparing the efficacy of immunofluorescent staining with Giemsa staining in detecting Chlamydia in conjunctival scrapings from cases of active trachoma is presented. Sixty-two eyes o...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00133786
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate the accuracy of the convolutional neural network (CNN) model in glaucoma identification with three primary colors (red, green, blue; RGB) and split color channels using fundus photographs with a small sample size. METHODS:The dataset was prepared using color fundus pho...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01485-3
更新日期:2020-11-01 00:00:00
abstract::Glycated proteins formed by the Maillard reaction were measured by furosine determination in human normal lenses and in senile and diabetic cataracts. Furosine, an hydrolysis product of fructose-lysine adduct formed in the early stages of the Maillard reaction, was measured by high performance liquid chromatography (H...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00951795
更新日期:1994-01-01 00:00:00
abstract::We report the first case of ischaemic optic neuropathy (ION) linked to chronic myelomonocytic leukaemia (CMML) and its associated vasculitis. We discuss the link between CMML and vasculitis and the evidence suggesting it can cause anterior ischaemic optic neuropathy through a vasculitic process. We highlight the diffi...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9675-5
更新日期:2013-08-01 00:00:00
abstract::To investigate long-term clinical outcomes after acute angle closure in the Chinese population. A 10-year retrospective review of primary acute angle closure in Hong Kong Chinese to document patient demographics, treatment, and pre- and post-acute angle closure intraocular pressure (IOP) and visual acuity (VA). The ye...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9806-7
更新日期:2014-04-01 00:00:00