Abstract：
PURPOSE:To identify baseline optical coherence tomography (OCT) factors in ischemic central retinal vein occlusion (CRVO) that predict response to bevacizumab injections. METHODS:Patients underwent OCT at diagnosis and the central macular thickness, subretinal fluid width and height as well as the presence of intraretinal cysts were measured. The extent of disorganized retinal inner layers, outer plexiform layer (OPL), external limiting membrane, ellipsoid zone and cone outer segment tips (COST) was recorded. Patients received three consecutive monthly injections of bevacizumab followed by pro re nata treatment. RESULTS:Overall 32 eyes of 32 patients aging 69.4 ± 12.7 years were included. In univariate correlational analyses baseline OPL disruption (- 41, p = 0.02), EZ disruption (r = - 0.36, p = 0.05) and COST disruption (r = - 0.37, p = 0.04) correlated with deterioration in BCVA at 1 year. Partial least squares demonstrated that the factors most largely associated with deterioration in BCVA were COST disruption and OPL disruption followed by EZ disruption, while worst vision at baseline was associated with improvement in vision. CONCLUSION:In patients with ischemic CRVO treated with bevacizumab, BCVA improvement at 1 year can be partially predicted from baseline OCT measurements by the extent of COST, OPL and EZ disruption.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Segal O,Mimouni M,Rabina G,Yavnieli R,Nemet AYdoi
10.1007/s10792-020-01604-0subject
Has Abstractpub_date
2020-10-22 00:00:00eissn
0165-5701issn
1573-2630pii
10.1007/s10792-020-01604-0pub_type
杂志文章abstract：OBJECTIVES:To evaluate the use of Optical Coherence Tomography (OCT) in the diagnosis of macular edema (ME) in diabetic patients in comparison to indirect ophthalmoscopy (IO) and, in addition, to study the characteristics of these patients. METHODS:165 patients were randomly selected to join the study in 1998. Ophthal...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/b:inte.0000006784.52885.e9
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To identify risk factors for endogenous endophthalmitis (EE) in hospitalized adults, under 65 years of age, with a history of intravenous opioid use and non-ocular infection. METHODS:The National Inpatient Sample Database was used to identify cases of EE with a recent history of intravenous opioid use disorder...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-021-01709-0
更新日期：2021-01-27 00:00:00
abstract：PURPOSE:To investigate the effects of glaucomatous damage on the mfVEP parameters of patients suffering from primary open-angle glaucoma (POAG). METHODS:Fifteen healthy subjects and 15 patients with unilateral POAG participated in this study. In addition, routine ophthalmological examinations including visual acuity, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01138-0
更新日期：2019-12-01 00:00:00
abstract：:Thirty-three cases of aphakic retinal detachment have been treated by pars plana vitrectomy and retinopexy. This procedure allowed us to lower the incidence of postoperative massive periretinal proliferation from 15,4%, in a series that was performed by a classical method, to 6% in the pars plana treated group. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00138265
更新日期：1984-01-01 00:00:00
abstract：:Sarcoidosis is a multisystem disease characterized by enhanced immune responses at sites of involvement. To elucidate the immunopathogenesis of ophthalmic lesions, cell infiltrates in biopsies from conjunctiva and other tissues involved (lungs, lymph nodes, skin) were studied in 26 patients with active sarcoidosis in ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00131162
更新日期：1990-01-01 00:00:00
abstract：:We report our experience with photodynamic therapy (PDT) in the treatment of choroidal neovascularization (CNV) in young adult patients. This was a retrospective study of young adults with CNV treated with PDT. Data collected included age, diagnosis, type and size of CNV, number of treatments, visual outcome, and side...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9346-3
更新日期：2010-08-01 00:00:00
abstract：:A 17-year-old female presented to our hospital with fatigue, arthralgia and fever associated with non-granulomatous anterior uveitis in the left eye. Blood tests revealed renal failure and a renal biopsy showed acute tubulointerstitial nephritis. Findings were consistent with tubulointerstitial nephritis and uveitis (...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9820-9
更新日期：2014-06-01 00:00:00
abstract：:This study aimed to present precancerous and cancerous epithelial eyelid lesions, their histopathological features, and possible correlations with clinical parameters. The retrospective study included 147 formalin-fixed, paraffin-embedded samples. We studied precancerous and cancerous epithelial eyelid lesions. Preneo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0258-8
更新日期：2017-02-01 00:00:00
abstract：:Onchocerciasis is a devastating blinding disease caused by the parasite Onchocerca volvulus that infects about 80 million people, causing blindness and visual impairment in 1-2 million people. In hyperendemic areas, more than half of the population will become blind from onchocerciasis before they die. Blindness is th...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00158317
更新日期：1990-05-01 00:00:00
abstract：PURPOSE:To evaluate and compare outcomes of CO2 laser-assisted sclerectomy surgery (CLASS) with mitomycin C (MMC) combined with or without phacoemulsification in adult Asian glaucoma patients. DESIGN:Retrospective, comparative study. METHODS:Adult Asian glaucoma patients who underwent CLASS alone or combined with pha...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-021-01707-2
更新日期：2021-01-22 00:00:00
abstract：:A case of orbital metastasis of cervical keratinizing squamous cell carcinoma is presented. The patient, in remission from primary cervical and ovarian cancers, presented with complaints of left eye ptosis and pain. Examination revealed the presence of a moderately tender mass along the left supra-temporal orbital rim...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9162-6
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy. METHODS:Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations ...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-017-0685-1
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:To present recurrent corneal erosion (RCE) caused by late suture exposure after blepharoplasty. METHODS:Four patients who have unilateral RCE were found to have previous blepharoplasty. The RCE was associated with late suture exposure. The clinical courses, characteristics, methods to identify the suture expos...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0936-9
更新日期：2019-06-01 00:00:00
abstract：:The association between HLA-A29 and birdshot chorioretinopathy is the strongest of all associations between HLA and disease. Determination of HLA-A29 is even of diagnostic significance. The association between HLA-B27 and acute anterior uveitis (AAU) is much weaker, but B27 positive AAU may be considered as a distinct...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00163552
更新日期：1990-10-01 00:00:00
abstract：:The study aims to determine the progression of gyrate atrophy by measuring the area growth of chorioretinal atrophic lesions using ultra-wide-field images (UWFI). A retrospective, observational, and comparative study was conducted and UWFI (200°) were obtained from two patients with gyrate atrophy at baseline and foll...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0085-3
更新日期：2016-02-01 00:00:00
abstract：:The purpose of the study is to determine the incidence and distribution of paravascular lamellar holes (PLH) around retinal vessels in highly myopic eyes and their relationship with macular retinoschisis (MR). We examined 306 eyes of 178 patients with high myopia, performing multiple scans of the posterior pole within...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0110-6
更新日期：2016-04-01 00:00:00
abstract：PURPOSE:To examine the retinal layers' changes and alterations in retinal microvasculature in patients with rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy (PPV). METHODS:Participants in this study were 103 patients with RRD, 85 macula off and 18 macula on, who were treated with PPV and gas ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01521-2
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To report a case with acute endophthalmitis as a postoperative complication of 25-gauge transconjunctival sutureless vitrectomy. METHODS:A 65-year-old gentleman, who underwent 25-gauge sutureless vitrectomy for an idiopathic epiretinal membrane at Beyoğlu Eye Research and Training Hospital, presented with pain...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9081-6
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:To assess the comprehensive effects of raloxifene hydrochloride on retinal, choroidal and retrobulbar hemodynamics and on visual function in post-menopausal women. DESIGN:Twenty-four post-menopausal women (age 55 +/- 3.8 years) were recruited for this cross-sectional study: 12 received placebo and 12 receive...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-008-9224-4
更新日期：2009-08-01 00:00:00
abstract：PURPOSE:To evaluate superficial capillary plexus (SCP) changes occurring after internal limiting membrane (ILM) peeling for the treatment of idiopathic epiretinal membrane (ERM). METHODS:A total of 15 eyes of 15 patients affected by idiopathic ERM (eight males and seven females; mean age 59.8 ± 9.6 years) were enrolle...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0608-1
更新日期：2018-08-01 00:00:00
abstract：:In order to evaluate possible etiological factors and the natural course of 'idiopathic' preretinal fibrosis in young persons, nine consecutive patients with macular pucker diagnosed under the age of 50 years were examined. There were six women and three men with the mean age of 27.2 years (range 15-50) and the mean f...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00202776
更新日期：1987-02-01 00:00:00
abstract：PURPOSE:To study the connective tissue (CT) structure of upper eyelid skin of primary open-angle glaucoma (POAG) patients. PATIENTS AND METHODS:Forty-seven patients aged 47-91 expecting blepharoplasty formed 3 groups: group 1 [16 subjects without POAG, median age 55 years (interquartile range 54-55.5)], group 2 [12 su...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1035-7
更新日期：2019-09-01 00:00:00
abstract：:Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus ...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-008-9223-5
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Autoenucleation is a severe, rare form of self-mutilation. The majority of cases have been reported in the 15- to 60-year age group, usually in psychiatric patients with a history of depression or schizophrenia, sometimes caused by drug abuse. CASE REPORT:We report a case of left-sided autoenucleation in an...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9222-6
更新日期：2009-08-01 00:00:00
abstract：:Aqueous flare and cells are the two inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barriers. When examined with the slit lamp, measurement of intraocular inflammation remains subjective with considerable intra- and interobserver variations. Laser flare cell photo...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-009-9310-2
更新日期：2010-10-01 00:00:00
abstract：:Pigmented rabbits were treated with timolol maleate, betaxolol hydrochloride or levobunolol hydrochloride eye drops twice a day for six months. Animals of the same age group and breed were used as controls. There were no differences observed in corneal epithelium with light and transmission electron microscopy. With s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02028643
更新日期：1989-01-01 00:00:00
abstract：:Current theories for macular hole formation implicate antero-posterior and tractional forces at the vitreofoveal interface. It is thought that localized perifoveal defects enlarge from centrifugal forces acting about the axis of ocular rotation. If this is true, eyes with longer axial lengths should have an increased ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9568-7
更新日期：2012-08-01 00:00:00
abstract：:A young patient is described who presented with sudden visual loss in the left eye quickly followed by proliferative retinopathy with retinal detachment and thrombotic glaucoma. He developed similar initial symptoms in the right eye but has now made a complete recovery in that eye on systemic steroids, oral acyclovir,...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00163567
更新日期：1990-10-01 00:00:00
abstract：PURPOSES:This research aimed to investigate effects and risk factors on non-contact tonometer (NCT) readings in healthy myopic subjects by employing cross-sectional study design. METHODS:Totally, sixty otherwise healthy myopic volunteers (mean 28.4 years old) with 90% female were recruited in ophthalmic clinic. The ro...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01203-8
更新日期：2020-02-01 00:00:00
abstract：PURPOSE:To determine the efficacy of locally produced Latanoprost in reducing the intraocular pressure (IOP) in patients with Primary open-angle glaucoma (POAG). DESIGN:Open-label, non-comparative, observational case study with non-probability purposive sampling. METHODS:A total of 48 patients (94 eyes) of either gen...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-017-0773-2
更新日期：2018-12-01 00:00:00
