A diagnostic challenge: chronic myelomonocytic leukaemia and recurrent anterior ischaemic optic neuropathy.

Abstract:

:We report the first case of ischaemic optic neuropathy (ION) linked to chronic myelomonocytic leukaemia (CMML) and its associated vasculitis. We discuss the link between CMML and vasculitis and the evidence suggesting it can cause anterior ischaemic optic neuropathy through a vasculitic process. We highlight the difficulty and delay in diagnosis as the use of steroids masked an underlying systemic process. Recurrent ION and raised inflammatory markers should raise suspicion of vasculitis. Together with an elevated monocyte but low platelet count, CMML should be considered.

journal_name

Int Ophthalmol

authors

De Smit E,O'Sullivan E

doi

10.1007/s10792-012-9675-5

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

415-23

issue

4

eissn

0165-5701

issn

1573-2630

journal_volume

33

pub_type

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