Abstract：
PURPOSE:To analyze the relationship between the seasonal allergic conjunctivitis (SAC), eotaxin-2, matrix metalloproteinase-9 (MMP-9), and the topographical findings in the keratoconus patients. METHODS:Thirty-four eyes of patients without SAC (Group 1), 34 eyes of patients with SAC (Group 2), and 20 eyes of control subjects (control group) were enrolled. Tear samples of the subjects were collected by Schirmer method. Corneal topography parameters, tear MMP-9, and tear eotaxin-2 levels were analyzed. RESULTS:The mean tear MMP-9 levels in Groups 1 and 2 were significantly higher than in the control group (p = 0.004). MMP-9 level exhibited a positive correlation with the keratoconus stage and a negative correlation with the thinnest corneal thickness (r = 0.294, p = 0.018, and r = - 0.302, p = 0.006, respectively). The tear eotaxin-2 level was higher in Group 2 than in Group 1 and control group which is not statistically significant (p = 0.17). CONCLUSION:The tear eotaxin-2 did not exhibit any difference in the presence of keratoconus. The tear MMP-9 level was higher in the keratoconic eyes, and it showed a correlation with the stage of the disease and the corneal thickness.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Mutlu M,Sarac O,Cağıl N,Avcıoğlu Gdoi
10.1007/s10792-019-01149-xsubject
Has Abstractpub_date
2020-01-01 00:00:00pages
51-57issue
1eissn
0165-5701issn
1573-2630pii
10.1007/s10792-019-01149-xjournal_volume
40pub_type
杂志文章abstract：:Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus ...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
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更新日期：2008-06-01 00:00:00
abstract：PURPOSE:To describe the incidence of, and risk factors associated with, diabetic retinopathy in diabetic persons assessed at a Saudi diabetes centre. METHODS:Five hundred and two patients with diabetes mellitus assessed by our service were studied. There were 174 patients (34.7%) with insulin-dependent diabetes mellit...
journal_title：International ophthalmology
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更新日期：1998-01-01 00:00:00
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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更新日期：1997-01-01 00:00:00
abstract：:Sensorineural hearing loss is the most common disease associated with systemic retinitis pigmentosa (RP). We have conducted an epidemiological study to assess the correlation of age at onset of visual symptoms and hearing loss associated with RP. Epidemiological data was derived from a questionnaire-based study of pat...
journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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更新日期：1998-01-01 00:00:00
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journal_title：International ophthalmology
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更新日期：1987-08-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
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更新日期：2020-03-01 00:00:00
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journal_title：International ophthalmology
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更新日期：1996-01-01 00:00:00
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
