Abstract:
PURPOSE:The study aims to evaluate changes in neopterin levels and tryptophan degradation which are induced by Th1-type immune response and nitric oxide metabolism which may be involved in allergic inflammation. METHODS:Serum nitrite, kynurenine, tryptophan and neopterin levels were evaluated in 36 patients with seasonal allergic conjunctivitis, along with these values in 41 healthy subjects. All these parameters have been compared with symptom and sign scores. RESULTS:Tryptophan and kynurenine concentrations were not significantly changed, while serum nitrite concentrations were significantly low, and neopterin levels were significantly increased in patients compared to healthy subjects (p < 0.05). There was a significant relationship between symptom scores and serum nitrite levels in patients. CONCLUSIONS:This preliminary study demonstrates that serum nitric oxide metabolism might have a role in allergic conjunctivitis. Serum neopterin levels but not tryptophan metabolism could serve as a biomarker in patients with seasonal allergic conjunctivitis.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Cinici E,Palabiyik SS,Sipahi H,Baydar Tdoi
10.1007/s10792-017-0669-1subject
Has Abstractpub_date
2018-10-01 00:00:00pages
1871-1878issue
5eissn
0165-5701issn
1573-2630pii
10.1007/s10792-017-0669-1journal_volume
38pub_type
杂志文章abstract:PURPOSE:To introduce a case of ciliary detachment with primary pulmonary hypertension (PPH). METHODS:The clinical manifestations of a case of ciliary detachment with PPH were addressed by comprehensive examination including ultrasound biological microscope (UBM), intraocular pressure, color fundus photographs, fluores...
journal_title:International ophthalmology
pub_type: 杂志文章
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更新日期:2018-02-01 00:00:00
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journal_title:International ophthalmology
pub_type: 杂志文章,评审
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更新日期:2020-12-01 00:00:00
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journal_title:International ophthalmology
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更新日期:2013-12-01 00:00:00
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更新日期:2019-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2001-01-01 00:00:00
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pub_type: 杂志文章,已发布勘误
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更新日期:2019-01-01 00:00:00
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更新日期:1985-04-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2014-02-01 00:00:00
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更新日期:2005-06-01 00:00:00
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更新日期:2017-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
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更新日期:2013-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-10-01 00:00:00