Abstract：
BACKGROUND:Optic disc drusen (ODD) are acellular deposits in the prelaminar optic nerve head. The most accredited theory is that they are secondary to abnormalities in axonal metabolism and degeneration, but the pathogenesis is not clear to date. CLINICAL MANIFESTATION:Although ODD are often considered a benign condition, the great majority of patients with ODD show visual field defects and are at higher risk for developing anterior ischemic optic neuropathy. ODD are classified as superficial or buried, with the latter being often misdiagnosed as papilledema with optic nerve head swelling, leading to an unnecessary investigation for causes of increased intracranial pressure. AIM:The recent technological improvements in OCT imaging which allowed an earlier and more certain diagnosis even of the smallest ODD, renovated the interest around this pathology. However, an updated systematic review is still missing. Therefore, the aim of this work is to provide a concise yet comprehensive overview of the current state of art, focusing on pathophysiology, clinical presentation, diagnostic methods, treatment modalities and potential future perspectives of this condition.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Allegrini D,Pagano L,Ferrara M,Borgia A,Sorrentino T,Montesano G,Angi M,Romano MRdoi
10.1007/s10792-020-01365-wsubject
Has Abstractpub_date
2020-08-01 00:00:00pages
2119-2127issue
8eissn
0165-5701issn
1573-2630pii
10.1007/s10792-020-01365-wjournal_volume
40pub_type
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journal_title：International ophthalmology
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