Abstract：
PURPOSE:This study evaluates the outcomes of ruthenium-106 (Ru-106) plaque brachytherapy for vasoproliferative tumors (VPTs) of the ocular fundus in a single referral ocular oncology center. METHODS:The clinical charts of all patients diagnosed with VPT who underwent plaque radiotherapy from 2002 to 2017 were reviewed. Clinical features, types of treatment, outcomes and complications were evaluated. RESULTS:Of 46 patients with VPT diagnosis in our ocular oncology clinic, 25 (54.34%) cases were treated with Ru-106 plaque brachytherapy. Eleven patients (44%) were male, and the mean age at the time of diagnosis was 40.92 ± 13.11 years. The mean follow-up time was 47.56 ± 36.87 months. Inferotemporal quadrant was the most common site of the tumor (64.00%). The mean delivered apex and scleral dose was 101.56 ± 6.51 and 412.26 ± 113.66 Gray (Gy), respectively. Initial tumor length, width and thickness were 10.26 ± 3.42, 8.05 ± 2.83 and 4.27 ± 1.10 mm, respectively. The mean tumor thickness decreased to 2.60 ± 0.63 mm, postoperatively. Complete resolution of subretinal fluid around the tumor was achieved in 81.80% of cases. Visual acuity was more than 20/400 in 64% of patients before treatment and 60% of patients at last follow-up. CONCLUSION:Our study showed that Ru-106 plaque radiotherapy is an effective and safe method of treatment in VPTs.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Abolfathzadeh N,Naseripour M,Jaberi R,Azma Z,Alemzadeh SA,Arbab M,Sedaghat Adoi
10.1007/s10792-020-01386-5subject
Has Abstractpub_date
2020-08-01 00:00:00pages
2095-2102issue
8eissn
0165-5701issn
1573-2630pii
10.1007/s10792-020-01386-5journal_volume
40pub_type
杂志文章abstract：:A 32-year-old lady presented with bilateral painful proptosis and left infranuclear facial palsy. She was mildly anemic. Ocular examination revealed a firm non-tender mass in the super lateral quadrant of both orbits. Fine-needle aspiration cytology from the orbital mass showed the presence of lymphoplasmacytoid cells...
journal_title：International ophthalmology
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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更新日期：1984-01-01 00:00:00
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journal_title：International ophthalmology
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journal_title：International ophthalmology
pub_type： 杂志文章
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