Conjunctival mucoepithelial hyperplasia of the elderly.

Abstract:

:The ocular surface is exposed to many chronic inflammatory stimuli, and goblet cell hyperplasia of the conjunctiva occurs in many situations. We report two cases of epithelial goblet cell hyperplasia with nonspecific chronic inflammation which occurred on the internal canthus of elderly people. These cases shared the same clinicopathological features that mimicked neoplastic lesion macroscopically, but are composed of nonspecific inflammatory changes pathologically. Immunostaining of the tissue showed few IgG4+ plasma cells, and no neoplastic changes were observed. Both cases arose in elderly patients over the age of 80 years. Pathogenesis and clinical significance of the lesion is unclear, but it might be age related. Recognition of this diagnosis might help us avoid overdiagnosis of malignancy and to reach the correct diagnosis.

journal_name

Int Ophthalmol

authors

Ohashi A,Elsayed AA,Yasuma T,Iijima T,Nakamura S

doi

10.1007/s10792-015-0083-5

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

611-4

issue

4

eissn

0165-5701

issn

1573-2630

journal_volume

35

pub_type

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