Abstract：
:To investigate the efficacy of anti-tuberculous therapy and systemic corticosteroids in patients suffering from active presumed tuberculous choroiditis by the assessment of central retinal sensitivity and fixation characteristics. Six patients (six eyes) with active presumed tuberculous choroiditis were treated with anti-tuberculous therapy and systemic corticosteroids. Mean central retinal sensitivities and fixation stability and location were investigated with MP-1 microperimetry before and after treatment. After a mean follow-up of 11.33 ± 7.53 months (range 6-24 months), all eyes showed resolution of inflammation, with no recurrences, associated with a significant improvement in visual acuity (P = 0.003). At the baseline, mean central retinal sensitivities were 2.03 ± 2.46 dB (range 0.0-6.6 dB). Fixation was stable and predominantly central in three eyes, and unstable and predominantly eccentric in three eyes. After treatment at a mean of 9.33 ± 6.56 months (range 4-20 months), mean central retinal sensitivities improved to 9.65 ± 5.35 dB (range 2.4-15.2 dB) (P = 0.004) and fixation became predominantly central and stable in all eyes. Anti-tuberculous therapy combined with systemic corticosteroids improves central retinal sensitivity and fixation characteristics in patients with presumed tuberculous choroiditis.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Abu El-Asrar AM,Al-Mezaine HSdoi
10.1007/s10792-010-9371-2subject
Has Abstractpub_date
2010-10-01 00:00:00pages
567-76issue
5eissn
0165-5701issn
1573-2630journal_volume
30pub_type
杂志文章abstract：PURPOSE:Growth factors are considered as key molecules that participating in fibrosis formation. This research aimed to clarify potential effects of p53 on regulation of transforming growth factor β (TGF-β) and fibrosis formation and investigate the associated mechanisms. METHODS:Vimentin was examined to identify huma...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01320-9
更新日期：2020-06-01 00:00:00
abstract：:We report a case of peripheral ulcerative keratitis associated with neutrophilic dermatosis of the dorsal hand, a recently described clinical entity. A 68-year-old man presented with concurrent peripheral ulcerative keratitis of the right eye and neutrophilic dermatosis of the dorsal hand causing pustular skin eruptio...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-011-9428-x
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:The purpose of the study was to assess adjuvant treatment with topical nonsteroidal anti-inflammatory drugs (NSAIDs) (0.9 % bromfenac, 0.1 % nepafenac, 0.5 % indomethacin, or 0.1 % diclofenac) in addition to topical steroidal treatment with 0.1 % dexamethasone and 0.3 % netilmicin for prevention of cystoid macu...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0374-5
更新日期：2017-10-01 00:00:00
abstract：:In a prospective study of untreated ocular hypertension 117 eyes were non-exfoliative and 20 eyes exfoliative. The percentage of optic disc pallor was significantly larger in the exfoliative than in the non-exfoliative group, whereas no significant differences were found in IOP or in the visual field. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02028632
更新日期：1989-01-01 00:00:00
abstract：:To evaluate the efficacy of golimumab on severe and frequent recurrent anterior uveitis in patients with HLA-B27-positive ankylosing spondylitis. In this study, 15 eyes of 12 HLA-B27-positive AS patients with resistant anterior uveitis who received 50 mg of subcutaneous golimumab (Gol) per month due to frequent uveiti...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0239-y
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:A study of the characteristics and the results obtained in 99 consecutive eyes operated on for rhegmatogenous retinal detachment associated with aphakia or pseudophakia in order to find the predictive factors of poor anatomical and functional results. METHODS:The authors retrospectively reviewed the files o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00176882
更新日期：1996-01-01 00:00:00
abstract：:Thirty-six of 39 published calculated doubling times (Td's) of uveal melanomas appeared to be longer than 60 days. Metastatic death occurs 35-40 Td's after dissemination. The shortest interval between dissemination and metastatic death in individual patients may, therefore, be calculated as 35 x 60 days = 6 years; the...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00918938
更新日期：1992-03-01 00:00:00
abstract：:We evaluated the in vitro effects of the 1.3 u wavelength of a Nd:YAG laser using a fiberoptic delivery system, with or without sapphire tips on ocular tissue. Conjunctival and retinal adhesions were achieved best with a noncontact technique compared with a contact method. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00155628
更新日期：1987-08-01 00:00:00
abstract：PURPOSE:To evaluate the accuracy of intraocular lens (IOL) power calculation in relation to optical biometry devices and refraction types. METHODS:Patients undergoing cataract phacoemulsification and insertion of the MX60 IOL were enrolled. Optical biometric measurements were performed with both IOLMaster 700 and Lens...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01355-y
更新日期：2020-07-01 00:00:00
abstract：:Onchocerciasis is a devastating blinding disease caused by the parasite Onchocerca volvulus that infects about 80 million people, causing blindness and visual impairment in 1-2 million people. In hyperendemic areas, more than half of the population will become blind from onchocerciasis before they die. Blindness is th...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00158317
更新日期：1990-05-01 00:00:00
abstract：PURPOSE:To determine the efficacy of locally produced Latanoprost in reducing the intraocular pressure (IOP) in patients with Primary open-angle glaucoma (POAG). DESIGN:Open-label, non-comparative, observational case study with non-probability purposive sampling. METHODS:A total of 48 patients (94 eyes) of either gen...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-017-0773-2
更新日期：2018-12-01 00:00:00
abstract：PURPOSE:Early predictors of diabetic complications may aid in the prevention and/or management of these complications. The aim of this cross-sectional study was to determine the predictive value of retinopathy for the presence of other diabetic complications. METHODS:The population studied comprised 648 patients with ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014409829614
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To investigate the antibacterial effect of topical anesthetic proparacaine on conjunctival flora. METHODS:One hundred and forty-four eyes of 72 patients awaiting cataract surgery were included in the study. A commercially available solution of proparacaine, preserved with benzalkonium chloride 0.01%, was insti...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1023/a:1026567912389
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:To identify baseline optical coherence tomography (OCT) factors in ischemic central retinal vein occlusion (CRVO) that predict response to bevacizumab injections. METHODS:Patients underwent OCT at diagnosis and the central macular thickness, subretinal fluid width and height as well as the presence of intraret...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01604-0
更新日期：2020-10-22 00:00:00
abstract：PURPOSE:To explore whether retrobulbar administration of nerve growth factor (NGF) can restore visual function of streptozotocin-induced diabetes rats. METHODS:A high-sucrose/high-fat diet and single injection of streptozotocin (STZ) were used in modeling diabetes. During week 13-15 after STZ injection, diabetic rats ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01537-8
更新日期：2020-12-01 00:00:00
abstract：:Central serous chorioretinopathy (CSCR) is characterized by neurosensory retinal detachment. Because the retina pigment epithelium and choroidal pathology is the current mechanism in CSCR, many studies in the literature focused on the outer retinal layers. There is little information about the functional or histologic...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0278-4
更新日期：2017-04-01 00:00:00
abstract：:Uveitis is a complex intraocular inflammatory disease resulting from several aetiological entities that are linked to geographical, genetic and socioeconomic variables. The purpose of this study was to provide an overview of the distribution patterns of uveitis as seen in a nationwide referral centre at a community ho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9359-y
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To explore the protective effect of probucol on human retinal Müller cells cultured in high glucose. METHODS:Primary Müller cells from human retinas were cultured in complete DMEM. Third-generation Müller cells were identified using glutamine synthetase (GS) antibody and randomly divided into three groups: nor...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01130-8
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:To investigate the diurnal fluctuations of macular vessel density (VD) in primary open-angle glaucoma (POAG) and healthy subjects using optical coherence tomography angiography. METHODS:A total of 22 POAG eyes and 15 healthy eyes were included in this study. Macular VD, intraocular pressure, and blood pressure...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01408-2
更新日期：2020-09-01 00:00:00
abstract：:We studied the changes in the thickness of the retinal nerve fiber layer (RNFL) after surgery for idiopathic macular hole (MH) using spectral-domain optical coherence tomography (SD-OCT). Twenty eyes of 20 consecutive patients who underwent vitrectomy to close a MH were studied. The peripapillary RNFL thickness was me...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9855-y
更新日期：2014-06-01 00:00:00
abstract：:17 patients with intraretinal magnetic foreign bodies and vitreous hemorrhage are reported. 15 patients underwent a primary surgical repair consisting of a watertight wound closure and removal of the already swelling cataractous lens in 5 cases. All patients had vitrectomy during the second postinjury week. The foreig...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02279868
更新日期：1989-09-01 00:00:00
abstract：PURPOSE:To estimate objective visual acuity in subjects suffering from cataract and age-related macular degeneration via the optokinetic response evoked by a non-conventional induction method (oktotype); in addition, to compare such objective outcome with the subjective acuity based on the ETDRS charts. METHODS:Patien...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1001-4
更新日期：2019-08-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to compare the macular and peripapillary capillary vessel density (CVD) and foveal avascular zone (FAZ) in amblyopic eyes of adults with their fellow eyes and with eyes of healthy controls using optical coherence tomography-angiography (OCT-A). METHODS:A total of 34 eyes of 17 pa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01345-0
更新日期：2020-07-01 00:00:00
abstract：PURPOSE:To report a case of DUSN from the Indian subcontinent and emphasize the importance of immediate photocoagulation. METHOD:Review of case record. RESULT:The referring ophthalmologist had photographed the subretinal worm but had not undertaken laser photocoagulation. On presentation to us the patient had feature...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9045-x
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVES:To evaluate the use of Optical Coherence Tomography (OCT) in the diagnosis of macular edema (ME) in diabetic patients in comparison to indirect ophthalmoscopy (IO) and, in addition, to study the characteristics of these patients. METHODS:165 patients were randomly selected to join the study in 1998. Ophthal...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/b:inte.0000006784.52885.e9
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To evaluate circular neodymium: YAG laser incision in cases of anterior capsular contraction syndrome (ACCS) by comparing it to radial Neodymium: YAG laser incision as for efficacy and safety. SETTINGS:Ophthalmology Department, Benha University Hospitals. METHODS:The study was done on 74 eyes of 66 patients w...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-019-01094-9
更新日期：2019-11-01 00:00:00
abstract：:Bietti crystalline corneoretinal dystrophy (BCD, MIM 210370) is a type of hereditary retinal disorder which commonly occurs in China. It is known that mutations in the CYP4V2 gene result in BCD. The purpose of this study was to investigate the case of a Chinese family and characterize the polymorphisms of the CYP4V2 g...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9686-2
更新日期：2013-06-01 00:00:00
abstract：:Diplopia is a very disturbing condition that has been reported as a complication of several surgical procedures. The following review aims to identify the ocular and nonocular surgical techniques more often associated with this undesirable result. Diplopia is reported as an adverse outcome of some neurosurgical proced...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9927-7
更新日期：2014-08-01 00:00:00
abstract：PURPOSE:To report a childhood case of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) carrying the R92Q variant with a vision-threatening bilateral panuveitis. METHODS:Case report and review of the literature. RESULTS:A 7-year-old boy presented with an active bilateral panuveitis and a macular ras...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-017-0785-y
更新日期：2019-01-01 00:00:00
abstract：:This paper builds on results of a previous paper on the prevalence of trachomatous visual impairment as the foundation for assessing the global burden of trachomatous blindness and low vision: approximately 2.9 million cases of trachomatous blindness and 3.8 million low visioned corresponding to a global prevalence of...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130921
更新日期：1995-01-01 00:00:00
