Abstract：
PURPOSE:To investigate the antibacterial effect of topical anesthetic proparacaine on conjunctival flora. METHODS:One hundred and forty-four eyes of 72 patients awaiting cataract surgery were included in the study. A commercially available solution of proparacaine, preserved with benzalkonium chloride 0.01%, was instilled in one eye of all subjects while the vehicle solution, including the same concentration of preservative in aqueous solution, was administered to the other eye. Conjunctival cultures were taken from all eyes before and 15 minutes after the instillation of proparacaine and the vehicle. RESULTS:Of the 144 eyes, 76 (52.8%) had positive-conjunctival cultures with the most commonly isolated organisms being coagulase-negative staphylococci in each group. Of the 76 culture-positive eyes, 40 (52.6%) received proparacaine and 36 (47.4%) the vehicle preparation. Fifteen minutes after the instillation of proparacaine and the vehicle eyedrops, four eyes (10%) and 12 eyes (33.3%) had culture-positive conjunctival smears, respectively. Proparacaine significantly reduced the number of culture-positive eyes (p = 0.0003), in contrast to the vehicle (p = 0.21). CONCLUSION:A topical anesthetic, proparacaine, demonstrates antibacterial effects on the conjunctival flora.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Oguz H,Oguz E,Karadede S,Aslan Gdoi
10.1023/a:1026567912389subject
Has Abstractpub_date
1999-01-01 00:00:00pages
117-20issue
2eissn
0165-5701issn
1573-2630journal_volume
23pub_type
临床试验,杂志文章,随机对照试验abstract：PURPOSE:This study evaluates the outcomes of ruthenium-106 (Ru-106) plaque brachytherapy for vasoproliferative tumors (VPTs) of the ocular fundus in a single referral ocular oncology center. METHODS:The clinical charts of all patients diagnosed with VPT who underwent plaque radiotherapy from 2002 to 2017 were reviewed...
journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：2020-08-01 00:00:00
abstract：:Risk factors for corneal transplantation failure include both immunologic factors, such as graft rejection, corneal neovascularization, and peripheral anterior synechiae, as well as non-immunologic factors, such as ocular surface disorders (OSD) and glaucoma. This review highlights the necessity of having healthy ocul...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
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abstract：:Lipoid proteinosis is a rare disorder involving multiple organ systems. The ocular manifestations are usually trivial, but greatly aid in the diagnosis. We describe a patient who presented to us with typical moniliform blepharosis. A brief description of relevance to the ophthalmologist and review of the literature fo...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
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journal_title：International ophthalmology
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abstract：:We report our experience with photodynamic therapy (PDT) in the treatment of choroidal neovascularization (CNV) in young adult patients. This was a retrospective study of young adults with CNV treated with PDT. Data collected included age, diagnosis, type and size of CNV, number of treatments, visual outcome, and side...
journal_title：International ophthalmology
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journal_title：International ophthalmology
pub_type： 杂志文章
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journal_title：International ophthalmology
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更新日期：2007-12-01 00:00:00
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journal_title：International ophthalmology
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journal_title：International ophthalmology
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更新日期：2018-12-01 00:00:00
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journal_title：International ophthalmology
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journal_title：International ophthalmology
pub_type： 杂志文章
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journal_title：International ophthalmology
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更新日期：2019-09-01 00:00:00
