Graft failure: II. Ocular surface complications.

Abstract:

:Risk factors for corneal transplantation failure include both immunologic factors, such as graft rejection, corneal neovascularization, and peripheral anterior synechiae, as well as non-immunologic factors, such as ocular surface disorders (OSD) and glaucoma. This review highlights the necessity of having healthy ocular surface epithelia, tears, and eyelids. It presents different types of OSD, their underlying pathology, and their impact on native cornea and corneal grafts. In addition, a range of proposed donor and surgical factors influencing surface integrity following corneal transplant are addressed. Current medical and surgical research, both pre- and post-operative that promise to further improve the outcome of corneal grafts in the context of OSD are discussed.

journal_name

Int Ophthalmol

authors

Al-Swailem SA

doi

10.1007/s10792-007-9127-9

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

175-89

issue

3

eissn

0165-5701

issn

1573-2630

journal_volume

28

pub_type

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