Abstract:
:Published data on growth rates of uveal melanomas and effects of treatment modalities raise important considerations. Dissemination from uveal melanomas starts after the tumour is larger than 7 mm diameter; growth from 7 to 10 mm diameter increases the risk of metastases incrementally to approximately 16%. Estimations of tumour doubling times indicate that metastatic death before 8 years is nearly always due to pre-therapeutic dissemination so that the impact on survival by therapy can only be assessed thereafter. Histopathology on irradiated melanomas reveals that reproductive activity has not been suppressed and the anticipated (and unfavourable) risk of metastases is not balanced by poor post-irradiation visual acuity. Also the psychological well-being of a patient with a functional fellow eye is better after primary enucleation. Conservative management is most appropriate for: small melanomas, patients with a short life expectancy, melanomas in a single functioning eye, and patients refusing enucleation.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Manschot WA,Lee WR,van Strik Rdoi
10.1007/BF00132688subject
Has Abstractpub_date
1995-01-01 00:00:00pages
203-9issue
4eissn
0165-5701issn
1573-2630journal_volume
19pub_type
杂志文章,评审abstract::The unifying principle underlying this classification system is: The more posterior the disease and the greater the amount of involved retinal vascular tissue, the more serious the disease. The staging of the disease at any given location expresses the natural history and evolution of events at the border between vasc...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00136454
更新日期:1985-04-01 00:00:00
abstract:PURPOSE:To investigate the changes in ocular higher-order aberrations (HOA) after trabeculectomy using mitomycin-C (MMC). METHODS:We retrospectively reviewed data for 63 eyes from 63 glaucoma patients who had undergone MMC augmented trabeculectomy. We measured intraocular pressure (IOP), refractive errors, anterior ch...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0802-1
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:To determine the inflammatory course and level of visual rehabilitation after cataract extraction and posterior chamber lens implantation in patients with Fuchs' heterochromic iridocyclitis complicated by cataract. METHODS:In a clinical trial, 32 eyes (visual acuity of 20/160 or worse) of 30 patients underw...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1023/a:1026490902566
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:To report a case with acute endophthalmitis as a postoperative complication of 25-gauge transconjunctival sutureless vitrectomy. METHODS:A 65-year-old gentleman, who underwent 25-gauge sutureless vitrectomy for an idiopathic epiretinal membrane at Beyoğlu Eye Research and Training Hospital, presented with pain...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9081-6
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To report the fluorescein fundus angiographic (FFA) findings in the different clinical stages of Vogt-Koyanagi-Harada (VKH) patients. METHODS:Retrospective, transversal and descriptive study. All patients underwent FFA at least in one occasion. Patients with incomplete clinical files or a deficient FFA were ex...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-006-9027-4
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To report a case of subtotal iridodialysis that was repaired using suturing with the assistance of a guide needle. PATIENT AND METHODS:A 52-year-old man had subtotal iridodialysis of approximately 300° with massive hyphema and vitreous hemorrhage after blunt trauma. The patient was treated with pars plana vitr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0465-y
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To compare the preoperative and postoperative measurements of optical low-coherence reflectometry (OLCR) biometry and assessment of its refractive predictability. METHODS:A total of 114 eyes of 102 patients who underwent cataract treatment were prospectively examined. The axial length (AL), central corneal thi...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0952-9
更新日期:2019-06-01 00:00:00
abstract::The purpose of this study was to evaluate the impact of intravitreal bevacizumab injections on the management and outcome of patients affected by retinal vein occlusions, their effectiveness on morphological and functional parameters, the modalities of long-term management and the need for additional laser treatment d...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-014-0002-1
更新日期:2014-12-01 00:00:00
abstract::We constructed a contact lens with an integrated pressure-sensing device. It is housed in a container with three force-sensing elements, each 120 degrees apart, enabling measurement of the appositional force, i.e., the force with which the instrument is held against the eye. In part 1 of the study, the lens' precision...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1006292102204
更新日期:1998-01-01 00:00:00
abstract::To evaluate subfoveal choroidal thickness of normal eyes with the use of the enhanced depth imaging technique of optical coherence tomography (EDI-OCT) and correlation of choroidal thickness with patient age. A retrospective analysis of 123 healthy eyes was performed. Age, gender, refractive state and spheric equivale...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9787-6
更新日期:2014-02-01 00:00:00
abstract::To evaluate the effect of intracameral carbachol on foveal thickness in patients who underwent uneventful cataract surgery. This retrospective study included two groups: the study group patients (group 1, n = 47 eyes) had uneventful cataract surgery and received only carbachol 0.01 % for miosis; the control group pati...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9579-4
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:Coagulase-negative staphylococci have been reported to be the most frequent cause of bacterial postoperative endophthalmitis. Biofilm formation is the major virulence factor of Staphylococcus epidermidis and is often associated with methicillin resistance. This study aims at evaluating the presence of biofilm-p...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0339-8
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Bevacizumab (Avastin) has been used as off-label treatment for the specific inhibition of the vascular endothelial growth factor (VEGF). Although only intravenous administration of the drug is approved in combination therapy of colorectal carcinoma, promising short-term results have been reported about its i...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9122-1
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:To evaluate and compare outcomes of CO2 laser-assisted sclerectomy surgery (CLASS) with mitomycin C (MMC) combined with or without phacoemulsification in adult Asian glaucoma patients. DESIGN:Retrospective, comparative study. METHODS:Adult Asian glaucoma patients who underwent CLASS alone or combined with pha...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-021-01707-2
更新日期:2021-01-22 00:00:00
abstract::To investigate subconjunctival bevacizumab as an adjuvant in first-time glaucoma filtration surgery, we conducted a non-comparative, interventional case series, enrolling consecutive patients with uncontrolled primary glaucomas. All patients underwent trabeculectomy with mitomycin C and received a 1.25 mg subconjuncti...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9704-4
更新日期:2013-12-01 00:00:00
abstract::IgG4-related disease is a recently defined inflammatory process characterized by IgG4-bearing plasma cells in the involved tissues. The most common sites of involvement are the pancreas, hepatobiliary tract, salivary glands, lymph nodes, retroperitoneum and orbit, especially the lacrimal glands. Other ocular or ocular...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-015-0070-x
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Our purpose is to describe a safe and easy technique for the removal of the BrightOcular cosmetic iris implants. Our technique involves cutting the implant into five parts rather than removal as a whole with less intraocular manipulation and no rotation of the implant. METHODS:We have used this technique in tw...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01328-1
更新日期:2020-06-01 00:00:00
abstract::The clinical and pathological presentation of Behçet's disease are discussed. Necrotising arteriolitis and phlebitis with thromboses are demonstrated when a rare enucleation specimen became available for examination in this condition. Immunohistochemical studies show mural IgG, IgA, and C3 deposits in episcleral and s...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00128365
更新日期:1985-03-01 00:00:00
abstract::Ectopic cilia are the most rare of cilial anomalies. We report a 27-year-old man who presents with tarsal conjunctival symptomatic ectopic cilia. On slit-lamp examination eversion of the lower eyelid demonstrated that several black-white cilia were protruding from the conjunctiva. ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9228-0
更新日期:2009-08-01 00:00:00
abstract::Transvitreal pars plana sclerotomy using the contact Nd:YAG laser with a sapphire probe was performed on a group of rabbit eyes and compared with a similar procedure performed with a Ziegler knife. Although the intraocular pressure (IOP) was lowered in both groups of animals, the reduction was greater and more lasting...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00130620
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Optic disc drusen (ODD) are acellular deposits in the prelaminar optic nerve head. The most accredited theory is that they are secondary to abnormalities in axonal metabolism and degeneration, but the pathogenesis is not clear to date. CLINICAL MANIFESTATION:Although ODD are often considered a benign condit...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-020-01365-w
更新日期:2020-08-01 00:00:00
abstract::To evaluate efficacy and safety of same site re-operation in eyes with failed trabeculectomy. A retrospective, noncomparative, interventional case series. We reviewed the medical records of 35 eyes of 35 patients who underwent same-site re-operation for failed trabeculectomy. The surgery involved a fornix-based perito...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9840-5
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To introduce a case of ciliary detachment with primary pulmonary hypertension (PPH). METHODS:The clinical manifestations of a case of ciliary detachment with PPH were addressed by comprehensive examination including ultrasound biological microscope (UBM), intraocular pressure, color fundus photographs, fluores...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0443-4
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:Proliferative vitreoretinopathy (PVR) is characterized by the formation of cellular membranes on the detached retina and also in the vitreous. Glial cells can be found in epiretinal and subretinal membranes from eyes with PVR, proliferative diabetic retinopathy (PDR), idiopathic macular pucker, uveitis and othe...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1022509614815
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy. METHODS:Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations ...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1007/s10792-017-0685-1
更新日期:2018-10-01 00:00:00
abstract::To study the efficacy and safety of sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft and to investigate the clinical outcomes. Thirty eyes of 30 patients with primary pterygia were treated in this institutional study with excision followed by sutureless amniotic membrane t...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1007/s10792-011-9488-y
更新日期:2011-12-01 00:00:00
abstract::The melanocytoma of the optic disc is a deeply-pigmented tumor located on the optic nerve head. In contrast to malignant melanoma, it appears to occur in equal frequency in whites and non-whites. Histologically, it consists of deeply-pigmented plump nervus cells with benign characteristics. No treatment is usually nec...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00133275
更新日期:1978-09-01 00:00:00
abstract:PURPOSE:To analyze the relationship between the seasonal allergic conjunctivitis (SAC), eotaxin-2, matrix metalloproteinase-9 (MMP-9), and the topographical findings in the keratoconus patients. METHODS:Thirty-four eyes of patients without SAC (Group 1), 34 eyes of patients with SAC (Group 2), and 20 eyes of control s...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01149-x
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To assess the level of awareness among UK ophthalmic surgeons of the potential risks from starch powdered surgical gloves during ophthalmic surgery and to show by electron microscopy that starch granule contamination can occur during ophthalmic surgery. SETTING:A sample (N = 46) of UK ophthalmologists from the...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1006392915801
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To compare the actual depth of the tunnel created with femtosecond laser for intracorneal ring segment (ICRS) implantation with the target depth in keratoconus patients. METHODS:In this mix design study, eligible keratoconus patients were identified through chart review. The inclusion criterion was a history o...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0595-2
更新日期:2018-08-01 00:00:00