Abstract：
PURPOSE:To compare early optical coherence tomography (OCT) changes in neuroretinal foveal thickness (NFT) after first versus repeated photodynamic treatment (PDT) in eyes with choroidal neovascularization (CNV) due to age-related macular degeneration (AMD). METHODS:This is a prospective comparative case series study. Consecutive AMD patients, treated with PDT due to subfoveal CNV, were enrolled. The eyes were divided into two groups: group A included eyes that had received the first initial treatment, and group B included eyes that had received repeated treatment. All eyes underwent serial examinations with OCT: prior to PDT, 1 h, and 3 months after the PDT. The primary outcome measure was early OCT change in NFT after PDT. RESULTS:Thirty-three eyes of 33 patients were included in this study; 16 in group A and 17 in group B. Optical coherence tomography showed a significant increase in NFT 1 h after PDT, as compared to pre-treatment status, in group A eyes (P = 0.008) but not in group B eyes (P = 0.731). Subretinal fluid was increased in both groups (93.8% and 88.2%, respectively), whereas intraretinal fluid was remarkably more increased in group A eyes (88%) than in group B eyes (59%). CONCLUSION:Early change in NFT, demonstrated on OCT, indicates that PDT causes different retinal response in primary versus repeated treatment of PDT for CNV due to AMD.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Landa G,Bukelman A,Katz H,Pollack Adoi
10.1007/s10792-007-9176-0subject
Has Abstractpub_date
2009-02-01 00:00:00pages
1-5issue
1eissn
0165-5701issn
1573-2630journal_volume
29pub_type
杂志文章abstract：BACKGROUND:Bevacizumab (Avastin) has been used as off-label treatment for the specific inhibition of the vascular endothelial growth factor (VEGF). Although only intravenous administration of the drug is approved in combination therapy of colorectal carcinoma, promising short-term results have been reported about its i...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9122-1
更新日期：2008-04-01 00:00:00
abstract：:The main visual field indices of Flammer and the analogous ones of Heijl have been compared based on a population of 113 glaucomatous visual fields. It is shown that for the population studied, the differences between the two sets of indices are negligible for Octopus G1 program results and that they may thus be used ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00128955
更新日期：1991-09-01 00:00:00
abstract：:Thirty-six of 39 published calculated doubling times (Td's) of uveal melanomas appeared to be longer than 60 days. Metastatic death occurs 35-40 Td's after dissemination. The shortest interval between dissemination and metastatic death in individual patients may, therefore, be calculated as 35 x 60 days = 6 years; the...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00918938
更新日期：1992-03-01 00:00:00
abstract：:The purpose of the study is to determine the incidence and distribution of paravascular lamellar holes (PLH) around retinal vessels in highly myopic eyes and their relationship with macular retinoschisis (MR). We examined 306 eyes of 178 patients with high myopia, performing multiple scans of the posterior pole within...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0110-6
更新日期：2016-04-01 00:00:00
abstract：PURPOSE:To evaluate the changes on optical coherence tomography angiography (OCTA) in macula-off rhegmatogenous retinal detachments (RRD) treated with pars plana vitrectomy (PPV) and silicone oil (SO) 5000-cSt tamponade. MATERIALS AND METHOD:Forty-five eyes with macula-off RRD treated with PPV and SO tamponade were en...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01516-z
更新日期：2020-12-01 00:00:00
abstract：:Onchocerciasis is a major blinding disease affecting at least 28 million people in Africa and Latin America. Although a large-scale vector control program has been highly successful in limiting transmission of infection in West Africa, there has not been a satisfactory form of treatment available for those already inf...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136735
更新日期：1987-12-01 00:00:00
abstract：:Onchocerciasis is a devastating blinding disease caused by the parasite Onchocerca volvulus that infects about 80 million people, causing blindness and visual impairment in 1-2 million people. In hyperendemic areas, more than half of the population will become blind from onchocerciasis before they die. Blindness is th...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00158317
更新日期：1990-05-01 00:00:00
abstract：:The aim of this study is to report the clinical outcome of a diabetic patient with optic nerve head neovascularization treated with an intravitreal injection of triamcinolone acetonide. A 52-year-old patient presented with clinically significant diffuse macular edema and optic nerve head neovascularization due to prol...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/b:inte.0000031740.85124.78
更新日期：2004-03-01 00:00:00
abstract：:The unifying principle underlying this classification system is: The more posterior the disease and the greater the amount of involved retinal vascular tissue, the more serious the disease. The staging of the disease at any given location expresses the natural history and evolution of events at the border between vasc...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136454
更新日期：1985-04-01 00:00:00
abstract：PURPOSE:Early predictors of diabetic complications may aid in the prevention and/or management of these complications. The aim of this cross-sectional study was to determine the predictive value of retinopathy for the presence of other diabetic complications. METHODS:The population studied comprised 648 patients with ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014409829614
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To report two cases of retinal vascular occlusion and associated subconjunctival hemorrhage in needle optic nerve injury during local bulbar anesthesia. METHODS:Surgical records of these two subjects who presented with acute vision loss after cataract extraction were studied, and systemic workup and ocular ima...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0539-x
更新日期：2018-06-01 00:00:00
abstract：UNLABELLED:We examined the immunocytochemical features of after cataract tissue and cataractous lens epithelium prior to cataract surgery and at the time of surgery. METHODS:This study included 23 cases. Antibodies against the following antigens were used: epidermal growth factor (EGF), EGF receptor (EGF-R), fibroblas...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1010640118852
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:To demonstrate differences in optic nerve head (ONH), retinal nerve fiber layer (RNFL), and macular thickness in patients with internal carotid artery (ICA) stenosis using spectral domain optical coherence tomography (SD-OCT). METHODS:A case-controlled study was conducted in 31 patients with a diagnosis of uni...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01642-8
更新日期：2020-11-10 00:00:00
abstract：INTRODUCTION:The aim of this study was to compare the macular and peripapillary capillary vessel density (CVD) and foveal avascular zone (FAZ) in amblyopic eyes of adults with their fellow eyes and with eyes of healthy controls using optical coherence tomography-angiography (OCT-A). METHODS:A total of 34 eyes of 17 pa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01345-0
更新日期：2020-07-01 00:00:00
abstract：PURPOSE:To report a case of bilateral Terson Syndrome with sub inner limiting membrane hemorrhage associated with a rare finding: perimacular fold. METHODS:The patient, a 34 years old female with aneurysmal subarachnoid hemorrhage and bilateral Terson syndrome was admitted to the Ophthalmology department, complaining ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0822-5
更新日期：2019-02-01 00:00:00
abstract：:Clinical trials are often used to evaluate the efficacy of a given treatment. The results of clinical trials however do not always agree with a clinician's experience or intuition. The merits and demerits of Clinical Trials versus Intuition are discussed by using the laser photocoagulation trials of Proliferative Diab...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00159835
更新日期：1986-05-01 00:00:00
abstract：:We constructed a contact lens with an integrated pressure-sensing device. It is housed in a container with three force-sensing elements, each 120 degrees apart, enabling measurement of the appositional force, i.e., the force with which the instrument is held against the eye. In part 1 of the study, the lens' precision...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006292102204
更新日期：1998-01-01 00:00:00
abstract：:We report an unusual case of disseminated cysticercosis having simultaneous intraocular and extraocular involvement. This 21-year-old male presented with recent loss of vision in one eye and history of a single seizure. Examination revealed intravitreal cysticercosis with exudative retinal detachment. Computed tomogra...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-005-8248-2
更新日期：2005-02-01 00:00:00
abstract：:To report the clinical and microbiological characteristics of infectious endophthalmitis after Boston type I keratoprosthesis (B-K-Pro) implantation. Retrospective analysis of 136 eyes that received a B-K-Pro type 1 between 1999 and 2012 was performed. Five eyes with a diagnosis of exogenous endophthalmitis after B-K-...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9994-9
更新日期：2015-10-01 00:00:00
abstract：:Ectopic cilia are the most rare of cilial anomalies. We report a 27-year-old man who presents with tarsal conjunctival symptomatic ectopic cilia. On slit-lamp examination eversion of the lower eyelid demonstrated that several black-white cilia were protruding from the conjunctiva. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9228-0
更新日期：2009-08-01 00:00:00
abstract：:Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus ...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-008-9223-5
更新日期：2008-06-01 00:00:00
abstract：:I have developed two protective caps that fit on the viewing windows of the indirect ophthalmoscope. These caps contain filters that absorb the argon laser beam and protect the operator's eyes during endolaser treatment. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00225937
更新日期：1986-04-01 00:00:00
abstract：:Strabismus is a well recognized complication of retrobulbar anesthesia for cataract surgery. This may manifest as either paresis or sometimes contracture (overaction) in the late stage. Management of the patient is tailored to the individual case. Herein, we report a patient with inferior rectus paresis and medial rec...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9342-7
更新日期：2010-08-01 00:00:00
abstract：PURPOSE:Traditional color vision tests depend on subjective judgments and are not suitable for infant children and subjects with cognitive dysfunction. We aimed to explore an objective and quantitative color vision testing method based on sweep steady-state visual evoked potentials (sweep SSVEPs) and compare the result...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01613-z
更新日期：2020-10-12 00:00:00
abstract：PURPOSE:To identify baseline optical coherence tomography (OCT) factors in ischemic central retinal vein occlusion (CRVO) that predict response to bevacizumab injections. METHODS:Patients underwent OCT at diagnosis and the central macular thickness, subretinal fluid width and height as well as the presence of intraret...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01604-0
更新日期：2020-10-22 00:00:00
abstract：:The purpose of this study was to evaluate the presence of Toxoplasmosis gondii in samples of peripheral blood from patients with varying etiologies of uveitis. Whole blood from patients with different forms of uveitis was tested for the presence of T. gondii using real-time PCR targeting the well-characterized 529 bp ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0221-8
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To evaluate rotational stability and visual and refractive outcomes of supplementary toric IOLs (Sulcoflex Toric 653T, Rayner Intraocular Lenses Ltd) for residual astigmatic refractive error in pseudophakic eyes. METHODS:A retrospective interventional case series was conducted in a single surgeon practice. Cha...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1027-7
更新日期：2019-09-01 00:00:00
abstract：:To investigate the correlation between the perifoveal capillary blood flow velocity (BFV) and the vitreous level of pigment epithelium-derived factor (PEDF) in patients with branch retinal vein occlusion (BRVO) and macular edema. In a retrospective interventional study of patients with BRVO and macular edema, undilute...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9584-7
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:With the increasing prevalence of electronic readers (e-readers) for vocational and professional uses, it is important to discover if there are visual consequences in the use of these products. There are no studies in the literature quantifying the incidence or severity of eyestrain, nor are there clinical c...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-016-0281-9
更新日期：2017-04-01 00:00:00
abstract：:The purpose of this study was to compare the keratometry (K) values obtained by the Scheimpflug camera combined with placido-disk corneal topography (Sirius) and optical biometry (Lenstar) for intraocular lens (IOL) power calculation before the cataract surgery, and to evaluate the accuracy of postoperative refraction...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0330-4
更新日期：2017-08-01 00:00:00
