Abstract：
:Onchocerciasis is a major blinding disease affecting at least 28 million people in Africa and Latin America. Although a large-scale vector control program has been highly successful in limiting transmission of infection in West Africa, there has not been a satisfactory form of treatment available for those already infected or those living in other areas. Despite the fact that two drugs, diethylcarbamazine and suramin, are active against the filarial parasite that causes onchocerciasis, their use is severely limited by their toxicity and the reaction they induce. A newly developed drug, ivermectin, appears to offer a major revolution in the treatment of onchocerciasis. In a series of clinical trials, ivermectin has been shown to be an extremely effective microfilaricide which induces only minimal side effects. Ivermectin is given as a single oral dose which can be repeated on an annual basis. In view of its safety and efficacy and its ease of administration, it seems likely that ivermectin will be suitable for use in mass chemotherapy programs against onchocerciasis.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Taylor HRdoi
10.1007/BF00136735subject
Has Abstractpub_date
1987-12-01 00:00:00pages
83-5issue
2eissn
0165-5701issn
1573-2630journal_volume
11pub_type
杂志文章abstract：:To assess the effect of intravitreal dexamethasone implant (Ozurdex) for the treatment of macular edema secondary to retinal vein occlusion (RVO) resistant to repeated intravitreal ranibizumab injection. Retrospective review of 11 patients (11 eyes) with ranibizumab-resistant macular edema secondary to RVO. Macular ed...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0226-3
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To investigate the effects of 1% cyclopentolate hydrochloride and 1% tropicamide eye drops on aqueous flare measurements by using the laser flare meter. METHODS:One hundred forty eight eyes of 83 patients with inactive uveitis were enrolled. The patients were randomly assigned to receive either 1% tropicamide ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01639-3
更新日期：2020-11-16 00:00:00
abstract：PURPOSE:To compare the actual depth of the tunnel created with femtosecond laser for intracorneal ring segment (ICRS) implantation with the target depth in keratoconus patients. METHODS:In this mix design study, eligible keratoconus patients were identified through chart review. The inclusion criterion was a history o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0595-2
更新日期：2018-08-01 00:00:00
abstract：PURPOSE:To evaluate by Environmental Scanning Electron Microscopy (ESEM) the corneal incision architecture after intraocular lens (IOL) implantation in pig eyes, using manual, automated injectors or preloaded delivery systems. METHODS:Twenty-four pig eyes underwent IOL implantation in the anterior chamber using three ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0825-2
更新日期：2019-02-01 00:00:00
abstract：PURPOSE:To report the fluorescein fundus angiographic (FFA) findings in the different clinical stages of Vogt-Koyanagi-Harada (VKH) patients. METHODS:Retrospective, transversal and descriptive study. All patients underwent FFA at least in one occasion. Patients with incomplete clinical files or a deficient FFA were ex...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-006-9027-4
更新日期：2007-04-01 00:00:00
abstract：PURPOSE:To investigate the natural course, visual outcome, and risk factors for visual loss after nonarteritic anterior ischemic optic neuropathy (NAION) attack in Chinese patients from a tertiary medical center in Southern Taiwan. METHODS:This is a longitudinal observational study that included sixty NAION patients, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01448-8
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:To report a case of toxic optic neuropathy caused by an ocular bee sting. METHODS:Case report and literature review. RESULTS:A 44-year-old female presented with no light perception vision 2 days after a corneal bee sting in her right eye. She was found to have diffuse cornea edema with overlying epithelial de...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0978-z
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:Aromatase inhibitors (anastrozole, letrozole) and selective estrogen receptor modulators (tamoxifen) are widely used as adjuvant hormonal therapy in women with hormone receptor-positive breast cancer. We aimed to evaluate the effects of oral adjuvant hormonotherapy on tear functions in patients with breast canc...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01384-7
更新日期：2020-08-01 00:00:00
abstract：:The aim of this study is to report the clinical outcome of a diabetic patient with optic nerve head neovascularization treated with an intravitreal injection of triamcinolone acetonide. A 52-year-old patient presented with clinically significant diffuse macular edema and optic nerve head neovascularization due to prol...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/b:inte.0000031740.85124.78
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:To evaluate the effect of metronidazole ophthalmic solutions on corneal neovascularization (CNV) in a rat model. METHODS:A chemical burn was created in the right central cornea of 40 rats. Animals were randomized and distributed into four study groups (n = 10 rats per group) designated Met_0.1%, Met_0.5%, sham...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0922-2
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To report the first European case of endogenous endophthalmitis secondary to a liver abscess due to Klebsiella pneumoniae expressing MagA gene. METHODS:A 33-year-old diabetic patient was admitted for fever and right upper quadrant abdominal pain. Abdominal computed tomography and laboratory studies were perfor...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9111-4
更新日期：2008-04-01 00:00:00
abstract：PURPOSE:To describe and evaluate the value of nutritional supplements in the management of age-related macular degeneration (AMD) through a review of the current literature. METHODS:An extensive literature search was performed, and key research articles exploring AREDS and AREDS-2 formulations, genetics, omega fatty a...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-019-01140-6
更新日期：2019-12-01 00:00:00
abstract：:The clinical and pathological presentation of Behçet's disease are discussed. Necrotising arteriolitis and phlebitis with thromboses are demonstrated when a rare enucleation specimen became available for examination in this condition. Immunohistochemical studies show mural IgG, IgA, and C3 deposits in episcleral and s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00128365
更新日期：1985-03-01 00:00:00
abstract：:Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus ...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-008-9223-5
更新日期：2008-06-01 00:00:00
abstract：:A 32-year-old lady presented with bilateral painful proptosis and left infranuclear facial palsy. She was mildly anemic. Ocular examination revealed a firm non-tender mass in the super lateral quadrant of both orbits. Fine-needle aspiration cytology from the orbital mass showed the presence of lymphoplasmacytoid cells...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9037-x
更新日期：2005-12-01 00:00:00
abstract：PURPOSE:Retinal vascular abnormalities are associated with choroidal melanoma. Although tumor ischemia, resulting in soluble angiogenic factor production, is a proposed etiology of these abnormalities, other sources of ischemia may also contribute. Mushroom-shaped choroidal melanomas have increased loss of the overlyin...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1021170402679
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To report a case of resolution of retinal arterial aneurysms in a patient of idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) treated with oral steroids. METHODS:This study contains case report and review of literature. RESULTS:A 16-year-old girl with stage 2 IRVAN was treated with oral ste...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0913-3
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To evaluate whether retrobulbar blood flow and choroidal thickness (CT) are affected in patients with rheumatoid arthritis (RA), and the relationship between these values. METHODS:We evaluated 40 eyes of 20 RA patients and 40 eyes of 20 healthy controls. The enhanced depth imaging optical coherence tomography,...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0656-6
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:To assess the effect of lateral rectus muscle resection on abduction in Duane retraction syndrome (DRS) type 1. METHODS:The medical records of patients with DRS type 1 were reviewed retrospectively. Fifteen patients who underwent lateral rectus resection were included. Prism and cover test and the Krimsky test...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01632-w
更新日期：2020-11-13 00:00:00
abstract：PURPOSE:To evaluate the cognitive performance of patients with glaucoma and compare it to individuals with Alzheimer's disease (AD). METHODS:This is a prospective, cross-sectional and case-control study. All subjects were assessed using the Mini-Mental State Examination (MMSE) and its subtests verbal fluency, word lis...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0658-4
更新日期：2018-10-01 00:00:00
abstract：:Management of retinoblastoma (Rb), the most common intraocular malignant tumor in childhood, is tailored to each individual case and based on the overall situation. We present a case of bilateral Rbs in a 4-month-old girl, referred to our center for bilateral leukocoria. In the right eye, the optic disc was partially ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9703-5
更新日期：2013-10-01 00:00:00
abstract：:We describe a case illustrating a new technique of using intraoperative optical coherence tomography (IOCT) for foreign body removal from the limbus and cornea. In this case, fragments of a fish hook in the temporal limbus and cornea were identified on the OCT. The residual pieces were then removed, assisted by high-r...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0304-6
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:Ripasudil accelerates aqueous humour drainage along the trabecular meshwork-Schlemm's canal route and has been approved for clinical use in Japan. We retrospectively investigated the efficacy and safety of adding ripasudil to existing treatment regimens to reduce intraocular pressure (IOP) in patients with glau...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0427-9
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:Few case reports have described vaso-occlusive retinopathy in systemic lupus erythematosus (SLE) using optical coherence tomography (OCT) angiography. Here we report the clinical features of a patient with SLE, complicated by Kikuchi-Fujimoto disease, who developed vaso-occlusive retinopathy. We then describe t...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0650-z
更新日期：2018-08-01 00:00:00
abstract：:A solitary fibrous tumor is a neoplasm generally arising from the mesothelial surfaces of the pleura and mesothelium. In this paper, we describe three cases of rare solitary fibrous tumors arising from the orbit and discuss the management of the tumors, including diagnosis and treatment. All three cases were treated b...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0421-2
更新日期：2018-02-01 00:00:00
abstract：:To evaluate the effect of intracameral carbachol on foveal thickness in patients who underwent uneventful cataract surgery. This retrospective study included two groups: the study group patients (group 1, n = 47 eyes) had uneventful cataract surgery and received only carbachol 0.01 % for miosis; the control group pati...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9579-4
更新日期：2012-10-01 00:00:00
abstract：:Pigmented rabbits were treated with timolol maleate, betaxolol hydrochloride or levobunolol hydrochloride eye drops twice a day for six months. Animals of the same age group and breed were used as controls. There were no differences observed in corneal epithelium with light and transmission electron microscopy. With s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02028643
更新日期：1989-01-01 00:00:00
abstract：:We encountered two cases of Harada's disease in monozygotic twins, and this is the first such report as far as could be determined. Case 1 was a 32-year-old woman who presented a typical clinical picture of Harada's disease. Seven years later, case 2 (the younger sister), also presented with the disease at 39 years of...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00917073
更新日期：1992-01-01 00:00:00
abstract：PURPOSE:To evaluate one-year visual, refractive, and topographic outcomes of 58 eyes of 53 keratoconus patients who underwent surgery with a progressive thickness intrastromal corneal ring segment (ICRS). METHODS:This multi-center, retrospective, observational study evaluates the one-year effects of progressive thickn...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01467-5
更新日期：2020-11-01 00:00:00
abstract：:Infrequently, vitreomacular traction is released through the spontaneous development of complete posterior vitreous detachment (PVD). PVD caused by laser photocoagulation has also been reported. A 62-year-old woman with ischemic branch retinal vein occlusion showed decreased vision in the affected eye due to vitreomac...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9166-2
更新日期：2009-02-01 00:00:00
