Abstract：
:Management of retinoblastoma (Rb), the most common intraocular malignant tumor in childhood, is tailored to each individual case and based on the overall situation. We present a case of bilateral Rbs in a 4-month-old girl, referred to our center for bilateral leukocoria. In the right eye, the optic disc was partially visible, and three large foci of retinoblastoma were noted adjective in the vitreous cavity with satellite retinal detachment. The macula was obscured by the tumors. The tumor was therefore classified as group D (International classification of retinoblastoma), and thus underwent intravenous chemotherapy with the standard three-agent protocol of ifosfamide, carboplatin and etoposide (ICE protocol) delivered monthly for six cycles, regressing with a type I calcified pattern. The left eye presented three multifocal yellow-white retinal masses, with a total retinal detachment, and secondary glaucoma. The lesions were classified as group E and, therefore, taking the results obtained by Shields et al. in group E tumors into consideration, underwent enucleation. This case clearly shows that this cancer is curable if detected at a stage in which it is still contained within the retina, subretinal space or vitreous, and that the management of Rb relies on an experienced team of ocular oncologists, pediatricians and pediatric ophthalmologists working together for the single goal of saving the child's life.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Pichi F,Lembo A,De Luca M,Hadjistilianou T,Nucci Pdoi
10.1007/s10792-012-9703-5subject
Has Abstractpub_date
2013-10-01 00:00:00pages
589-93issue
5eissn
0165-5701issn
1573-2630journal_volume
33pub_type
杂志文章abstract：:To describe a congenital retinal macrovessel with macular thickening. This case was investigated using fundus photography, fluorescein angiography, Spectralis optical coherence tomography and a 10-2 visual field test. A 23-year-old man was referred to our clinic with decreased vision in the right eye. Fundus examinati...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9402-z
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:To assess the effect of lateral rectus muscle resection on abduction in Duane retraction syndrome (DRS) type 1. METHODS:The medical records of patients with DRS type 1 were reviewed retrospectively. Fifteen patients who underwent lateral rectus resection were included. Prism and cover test and the Krimsky test...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01632-w
更新日期：2020-11-13 00:00:00
abstract：:The purpose of this study was to report various conditions masquerading as congenital nasolacrimal duct obstruction (CNLDO). Retrospective review was designed in a tertiary hospital setting. 92 eyes of 65 consecutive patients were included in this study. All patients presenting with CNLDO symptomatology but where the ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0050-1
更新日期：2015-12-01 00:00:00
abstract：:A 65-year-old woman with iridocorneal endothelial syndrome and a history of Ahmed glaucoma drainage (AGD) tube implantation underwent Descemet stripping automated endothelial keratoplasty (DSAEK) in her right eye. During the procedure, filling the anterior chamber with air was quite difficult due to escape of air via ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9603-8
更新日期：2012-12-01 00:00:00
abstract：:One hundred cases of clinically acceptable sympathetic ophthalmia (SO) were evaluated histologically to determine the incidence of atypical features and correlate them with the severity of choroidal inflammation. The inflammatory response in the choroid varied from a focal non-granulomatous to a diffuse non-necrotizin...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00161902
更新日期：1982-02-01 00:00:00
abstract：:To evaluate the potential benefit of intraocular pressure (IOP) reduction in normal-tension glaucoma (NTG) patients in South Korea. A retrospective, multi-center analysis of Korean NTG patients with 5-years follow-up, typical glaucomatous optic disc and/or visual field changes and no recorded IOP >21 mmHg. Progression...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
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更新日期：2011-10-01 00:00:00
abstract：PURPOSE:Numerous studies suggest that reactive oxygen species play a crucial role in the development of glaucoma. Since glaucoma patients exhibit posterior vitreous detachment earlier than controls, it has been suggested that reactive oxygen species-increased in glaucoma-also affect the vitreous. In the present study w...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01268-5
更新日期：2020-04-01 00:00:00
abstract：PURPOSE:To report a case of resolution of retinal arterial aneurysms in a patient of idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) treated with oral steroids. METHODS:This study contains case report and review of literature. RESULTS:A 16-year-old girl with stage 2 IRVAN was treated with oral ste...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
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更新日期：2019-05-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-006-9027-4
更新日期：2007-04-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章,评审
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更新日期：2008-06-01 00:00:00
abstract：:We constructed a contact lens with an integrated pressure-sensing device. It is housed in a container with three force-sensing elements, each 120 degrees apart, enabling measurement of the appositional force, i.e., the force with which the instrument is held against the eye. In part 1 of the study, the lens' precision...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006292102204
更新日期：1998-01-01 00:00:00
abstract：:To report the clinical and microbiological characteristics of infectious endophthalmitis after Boston type I keratoprosthesis (B-K-Pro) implantation. Retrospective analysis of 136 eyes that received a B-K-Pro type 1 between 1999 and 2012 was performed. Five eyes with a diagnosis of exogenous endophthalmitis after B-K-...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9994-9
更新日期：2015-10-01 00:00:00
abstract：:This retrospective study reviews the clinical and histopathological features of ocular epidermoid cyst. The 30-year laboratory records of all the patients of the Igbo ethnic group, whose surgical specimens were received at a central pathology laboratory service in south-eastern Nigeria, West Africa, were reviewed. The...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1025483024858
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Only a few studies have investigated structural and functional changes in monocular blind individuals. Our aim in this study was to segmentally investigate the cerebellar structures of subjects with late-onset monocular blindness (LMB) using a Voxel-based volumetric analysis system. METHODS:The segmental vo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01629-5
更新日期：2020-11-12 00:00:00
abstract：:To investigate the correlation between the perifoveal capillary blood flow velocity (BFV) and the vitreous level of pigment epithelium-derived factor (PEDF) in patients with branch retinal vein occlusion (BRVO) and macular edema. In a retrospective interventional study of patients with BRVO and macular edema, undilute...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9584-7
更新日期：2012-10-01 00:00:00
abstract：:Primary lacrimal sac melanoma is an extremely rare clinical entity with fewer than 25 cases reported in the literature. We present a well-documented case of lacrimal sac melanoma with anterior lacrimal crest infiltration and discuss the clinical, radiological and histopathological features along with surgical challeng...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9743-5
更新日期：2014-02-01 00:00:00
abstract：:The purpose of the study was to evaluate the outcomes and possible complications of CXL performed with customized epithelial debridement technique to keratoconic corneas with the thinnest pachymetry values less than 400 µm. Nineteen eyes of 19 patients were included. The uncorrected (UCVA) and best corrected visual ac...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0234-3
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Optic disc drusen (ODD) are acellular deposits in the prelaminar optic nerve head. The most accredited theory is that they are secondary to abnormalities in axonal metabolism and degeneration, but the pathogenesis is not clear to date. CLINICAL MANIFESTATION:Although ODD are often considered a benign condit...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-020-01365-w
更新日期：2020-08-01 00:00:00
abstract：:In the original publication, first line of methods under the Abstract section was published incorrectly. ...
journal_title：International ophthalmology
pub_type： 已发布勘误
doi：10.1007/s10792-020-01327-2
更新日期：2020-04-01 00:00:00
abstract：PURPOSE:To investigate complex and different phenotypes in seven Chinese patients diagnosed with Bardet-Biedl syndrome (BBS) and carrying pathogenic mutations. METHODS:Seven unrelated BBS patients were enrolled. Their medical and ophthalmic histories were reviewed, and comprehensive clinical examinations, such as fund...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01415-3
更新日期：2020-09-01 00:00:00
abstract：:There has been great controversy about the pathogenesis of the focal changes in the retinal pigment epithelium (RPE) causing detachment of the neurosensory retina in central serous chorioretinopathy (CSC). This study was performed to evaluate changes in choroidal perfusion in 15 patients with CSC. Fluorescein and indo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00133176
更新日期：1995-01-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-012-9588-3
更新日期：2012-10-01 00:00:00
abstract：:Infants have been known occasionally to stare without blinking for almost a minute. This puts great demands on the stability of their tear-film. To verify the stability of infant tears, we performed biophysical experiments on Meibomian gland secretion, which forms the outermost layer of the tear-film. The secretion wa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00919408
更新日期：1994-01-01 00:00:00
abstract：:The purpose of this paper was to describe a patient with pericentral retinitis pigmentosa (RP) and cystoid macular edema (CME) refractory to oral acetazolamide alone who was successfully treated with adjunctive pegaptanib sodium. A 33-year-old man presented with decreased vision and a best-corrected visual acuity (BCV...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9175-1
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To observe the effect of sirt1 on retinal ganglion cells (RGC) with high glucose culture and to explore the role of sirt1 in the development of diabetic retinopathy. Method RGC was infected by sirt1 lentivirus overexpression vector pLV5-sirt1 and interference vector pLV3-si-sirt1. The normal control group and...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01638-4
更新日期：2020-11-11 00:00:00
abstract：PURPOSE:To assess posterior inflammation using a fluorescein (FA)/indocyanine-green angiography (ICGA) scoring system, and compare them to the presently recommended outcome measure, the standardization of uveitis nomenclature vitreous haze score (SUN-VH) in stromal choroiditis. METHODS:This was a retrospective study o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0979-y
更新日期：2019-07-01 00:00:00
abstract：:An animal model of keratomycosis was used to study the interaction between the new enzyme antifungal compound mycolase II and the polyene antifungal antibiotic pimaricin. Well established corneal infection caused by an ocular pathogenic candida albicans on New Zealand white male rabbits were treated with 3% mycolase I...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00149150
更新日期：1982-11-01 00:00:00
abstract：PURPOSE:To describe the outcome of a series of Acanthamoeba keratitis treated with a similar regimen. METHODS:All cases diagnosed with Acanthamoeba keratitis in a referral centre from June 1994 through June 1997 were included. Diagnosis of Acanthamoeba keratitis was based in clinical presentation and laboratory result...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006055918101
更新日期：1997-01-01 00:00:00
abstract：:Invasive aspergillosis is a rare disease and is often misdiagnosed. The clinical course is quite aggressive and it is a potentially fatal disease. We report a case of invasive aspergillosis involving the dura mater and optic nerves which was successfully treated with voriconazole, even though the patient had residual ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9730-x
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:To describe the incidence of, and risk factors associated with, diabetic retinopathy in diabetic persons assessed at a Saudi diabetes centre. METHODS:Five hundred and two patients with diabetes mellitus assessed by our service were studied. There were 174 patients (34.7%) with insulin-dependent diabetes mellit...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006240928938
更新日期：1998-01-01 00:00:00
