Outcomes of corneal collagen crosslinking using a customized epithelial debridement technique in keratoconic eyes with thin corneas.

Abstract:

:The purpose of the study was to evaluate the outcomes and possible complications of CXL performed with customized epithelial debridement technique to keratoconic corneas with the thinnest pachymetry values less than 400 µm. Nineteen eyes of 19 patients were included. The uncorrected (UCVA) and best corrected visual acuity (BCVA), flattest and steepest keratometric (K) readings, central corneal thickness at the thinnest point (t-CCT), endothelial cell density (ECD) were assessed before and 12 months after CXL. The mean UCVA was increased (p = 0.001), while the mean BCVA did not show any difference (p > 0.05). The mean flattest and steepest K readings were decreased (p = 0.001). No change was observed in the mean t-CCT (p > 0.05). The mean ECD was decreased (p = 0.001). The mean pre-CXL and post-CXL percentages of polymegathism and pleomorphism did not show any significant difference (p > 0.05). CXL performed with customized epithelial debridement technique is successful in halting the progression of keratoconus in corneas thinner than 400 µm after 12 months of treatment. However, significant endothelial cell loss can occur after this procedure.

journal_name

Int Ophthalmol

authors

Cagil N,Sarac O,Can GD,Akcay E,Can ME

doi

10.1007/s10792-016-0234-3

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

103-109

issue

1

eissn

0165-5701

issn

1573-2630

pii

10.1007/s10792-016-0234-3

journal_volume

37

pub_type

杂志文章
  • Topical nonsteroidal anti-inflammatory drugs as adjuvant therapy in the prevention of macular edema after cataract surgery.

    abstract:PURPOSE:The purpose of the study was to assess adjuvant treatment with topical nonsteroidal anti-inflammatory drugs (NSAIDs) (0.9 % bromfenac, 0.1 % nepafenac, 0.5 % indomethacin, or 0.1 % diclofenac) in addition to topical steroidal treatment with 0.1 % dexamethasone and 0.3 % netilmicin for prevention of cystoid macu...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-016-0374-5

    authors: Cardascia N,Palmisano C,Centoducati T,Alessio G

    更新日期:2017-10-01 00:00:00

  • A comparison of three different intravitreal treatment modalities of macular edema due to branch retinal vein occlusion.

    abstract:PURPOSE:To compare the efficacy of intravitreal injection of ranibizumab, dexamethasone implant and aflibercept for the management of macular edema (ME) related to branch retinal vein occlusion (BRVO). METHODS:This retrospective and comparative study included 62 eyes of 62 patients with BRVO and ME. Patients received ...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-017-0618-z

    authors: Kaldırım HE,Yazgan S

    更新日期:2018-08-01 00:00:00

  • MTHFR and MTHFD1 gene polymorphisms are not associated with pseudoexfoliation syndrome in South Indian population.

    abstract:PURPOSE:Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PE...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-017-0498-2

    authors: Gopalakrishnan P,Haripriya A,Sundaresan P

    更新日期:2018-04-01 00:00:00

  • Morphometric evaluation of cerebellar structures in late monocular blindness.

    abstract:BACKGROUND:Only a few studies have investigated structural and functional changes in monocular blind individuals. Our aim in this study was to segmentally investigate the cerebellar structures of subjects with late-onset monocular blindness (LMB) using a Voxel-based volumetric analysis system. METHODS:The segmental vo...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01629-5

    authors: Özen Ö,Aslan F

    更新日期:2020-11-12 00:00:00

  • The effect of intravitreal bevacizumab injection before Ahmed valve implantation in patients with neovascular glaucoma.

    abstract::To evaluate the effect of intravitreal bevacizumab (IVB) before Ahmed valve implantation for treatment of neovascular glaucoma (NVG). This study is a retrospective, comparative, consecutive case series. The study group consisted of 27 eyes of 26 patients with NVG who underwent an Ahmed valve implantation. Thirteen eye...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-013-9875-7

    authors: Kang JY,Nam KY,Lee SJ,Lee SU

    更新日期:2014-08-01 00:00:00

  • Baseline demographics, clinical features, and treatment protocols of 240 patients with optic neuropathy: experiences from a neuro-ophthalmological clinic in the Aegean region of Turkey.

    abstract:PURPOSE:To analyze the demographic patterns, clinical characteristics, and treatment protocols of optic neuropathies. MATERIALS AND METHODS:The hospital data of patients with optic neuropathy admitted to the Department of Neuro-ophthalmology in a tertiary referral center in Turkey between January 2010 to January 2017 ...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-017-0799-5

    authors: Karti O,Karti DT,Kilic İH,Gokcay F,Celebisoy N

    更新日期:2019-01-01 00:00:00

  • A case of conjunctival MALT lymphoma: successfully treated with solely extended rituximab therapy.

    abstract:PURPOSE:Primary ocular adnexal lymphomas are cured by radiotherapy; however, complications are frequent and relapses may occur. In this case, we aimed to report the efficacy and safety of extended systemic rituximab (anti-CD 20 monoclonal antibody) therapy of conjunctival mucosa-associated lymphoid tissue (MALT) lympho...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-018-0844-z

    authors: Celiker H,Toker E,Kaygusuz Atagunduz I

    更新日期:2019-03-01 00:00:00

  • Creeping posterior synechiae following hyperopic iris-fixated phakic implants.

    abstract::The purpose of this study was to report on the occurrence and management of posterior synechiae (PS) in three hyperopic eyes after iris-fixated anterior chamber phakic IOL implantation. This is a case report of a 55-year-old man and a 55-year-old lady who had undergone iris-fixated anterior chamber phakic IOL implanta...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-016-0202-y

    authors: Messina M,Elalfy M,Fares U,Ghoz N,Mavi B,Dua H

    更新日期:2016-12-01 00:00:00

  • Glaucomatous optic nerve head changes with scanning laser ophthalmoscopy.

    abstract:PURPOSE:To determine whether there are angiographic differences among normal, preperimetric and advanced glaucoma eyes using indocyanine green angiography with SLO. This method was chosen because of its sensibility to detect peripapillary capillary vessels. METHODS:Scanning laser opthalmoscopy was preformed on normal ...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1023/a:1014431404096

    authors: Marengo J,Ucha RA,Martinez-Cartier M,Sampaolesi JR

    更新日期:2001-01-01 00:00:00

  • Strong fixation preference in patients with manifest exotropia: Does it matter or not?

    abstract:PURPOSE:To evaluate the influence of strong fixation preference on clinical and surgical outcomes, in non-amblyopic patients with basic-type intermittent exotropia (IXT). MATERIALS AND METHODS:The records of patients were retrospectively investigated. Non-amblyopic patients with the diagnosis of basic-type IXT were en...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01603-1

    authors: Cakir B,Aksoy NÖ,Bursalı Ö,Özmen S,Çelik E

    更新日期:2020-10-14 00:00:00

  • Intraocular pressure-lowering effects of ripasudil, a rho-kinase inhibitor, and selective laser trabeculoplasty as adjuvant therapy in patients with uncontrolled glaucoma.

    abstract:OBJECTIVES:To compare the intraocular pressure (IOP)-lowering effects of ripasudil, a rho-kinase inhibitor, and selective laser trabeculoplasty (SLT) as adjuvant therapy in Japanese glaucoma patients and to identify the factors associated with treatment success. METHODS:We performed a retrospective medical chart revie...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01615-x

    authors: Ono K,Sakemi F,Marumoto T

    更新日期:2020-10-20 00:00:00

  • Intravitreal triamcinolone acetonide for the management of papillophlebitis and associated macular edema.

    abstract:BACKGROUND:To investigate the efficacy of intravitreal injection of triamcinolone acetonide in the management of papillophlebitis and associated cystoid macular edema. METHODS:This study was a retrospective medical records review of four eyes of four patients (three males and one female) who had approximately 2-4 mont...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-007-9128-8

    authors: Chang YC,Wu WC

    更新日期:2008-08-01 00:00:00

  • Serum insulin-like growth factor-1 levels in patients with pseudoexfoliation syndrome and glaucoma.

    abstract::Insulin-like growth factor-1 (IGF-1) is altered in several neurodegenerative diseases, the association between serum IGF-1 levels and glaucoma has not been evaluated. This study was designed to evaluate whether serum IGF-1 levels are different in patients with Pseudoexfoliation (PEX) with or without glaucoma. The stud...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-016-0271-y

    authors: Dogan AS,Kabatas N,Erden G,Celikay O,Arzuhal AE,Gurdal C

    更新日期:2017-04-01 00:00:00

  • Ocular manifestations of rheumatic diseases.

    abstract:PURPOSE:Our aim was to summarize key aspects of the pathomechanism and the ocular involvements of rheumatic and systemic autoimmune diseases. METHODS:Apart from a paper in French (Morax V, Ann Oculist 109:368-370, 1893), all papers referred to in this article were published in English. All the materials were peer-revi...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-019-01183-9

    authors: Kemeny-Beke A,Szodoray P

    更新日期:2020-02-01 00:00:00

  • Successful treatment with adalimumab for severe multifocal choroiditis and panuveitis in presumed (early-onset) ocular sarcoidosis.

    abstract::Early-onset sarcoidosis (EOS) and Blau syndrome are rare auto-inflammatory diseases characterized by a triad of skin rash, granulomatous uveitis, and symmetrical polyarthritis occurring in early childhood. In this paper, we describe a case report very interesting for the multidisciplinary management (pediatric rheumat...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-015-0135-x

    authors: Achille M,Ilaria P,Teresa G,Roberto C,Ilir A,Piergiorgio N,Rolando C,Gabriele S

    更新日期:2016-02-01 00:00:00

  • Intracorneal ring segment depth in keratoconus patients: a long-term follow-up study.

    abstract:PURPOSE:To compare the actual depth of the tunnel created with femtosecond laser for intracorneal ring segment (ICRS) implantation with the target depth in keratoconus patients. METHODS:In this mix design study, eligible keratoconus patients were identified through chart review. The inclusion criterion was a history o...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-017-0595-2

    authors: Shahhoseini S,Hashemi H,Asgari S

    更新日期:2018-08-01 00:00:00

  • The acuityscope: a resolution test target projection ophthalmoscope.

    abstract::The Acuityscope projects an image of a three bar resolution test target onto the patient's retina, where it is viewed and read by an observer. The test target consists of a series of three bar targets varying in size on a logarithmic scale. Individual targets are identified in the projected image by Bailey-Lovie log v...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00224470

    authors: Brown NA,Sparrow JM,Shun-Shin GA,Franklin SL

    更新日期:1991-03-01 00:00:00

  • Observation of anterior chamber volume after cataract surgery with swept-source optical coherence tomography.

    abstract:PURPOSE:To investigate the changes in the anterior chamber volume (ACV) with swept-source optical coherence tomography (SS-OCT) after cataract surgery and the factors that influence these ACV changes. METHODS:This was a prospective cohort study. Fifty-one patients who underwent cataract surgery were enrolled. Their AC...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-018-1012-1

    authors: Chen M,Hu H,He W,Lu Y,Zhu X

    更新日期:2019-08-01 00:00:00

  • Clinical trials versus intuition in evaluating the results of laser photocoagulation.

    abstract::Clinical trials are often used to evaluate the efficacy of a given treatment. The results of clinical trials however do not always agree with a clinician's experience or intuition. The merits and demerits of Clinical Trials versus Intuition are discussed by using the laser photocoagulation trials of Proliferative Diab...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00159835

    authors: Wong D,Blach RK

    更新日期:1986-05-01 00:00:00

  • Graft failure: II. Ocular surface complications.

    abstract::Risk factors for corneal transplantation failure include both immunologic factors, such as graft rejection, corneal neovascularization, and peripheral anterior synechiae, as well as non-immunologic factors, such as ocular surface disorders (OSD) and glaucoma. This review highlights the necessity of having healthy ocul...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-007-9127-9

    authors: Al-Swailem SA

    更新日期:2008-06-01 00:00:00

  • Successful medical treatment of Acanthamoeba keratitis.

    abstract:PURPOSE:To describe the outcome of a series of Acanthamoeba keratitis treated with a similar regimen. METHODS:All cases diagnosed with Acanthamoeba keratitis in a referral centre from June 1994 through June 1997 were included. Diagnosis of Acanthamoeba keratitis was based in clinical presentation and laboratory result...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1023/a:1006055918101

    authors: Azuara-Blanco A,Sadiq AS,Hussain M,Lloyd JH,Dua HS

    更新日期:1997-01-01 00:00:00

  • Indocyanine green angiography findings in patients with neovascular age-related macular degeneration refractory to ranibizumab switched to aflibercept.

    abstract:PURPOSE:To describe indocyanine green angiography (ICGA) and visual acuity (VA) results in patients with neovascular age-related macular degeneration (nAMD) refractory to ranibizumab switched to aflibercept. METHODS:This study is a prospective interventional case series. Thirty-two eyes of 32 patients with nAMD showin...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-019-01082-z

    authors: Calvo-Gonzalez C,Reche-Frutos J,Fernández-Vigo JI,Donate-López J,Serrano-García I,Fernández-Pérez C

    更新日期:2019-11-01 00:00:00

  • Efficacy and safety of extemporaneously prepared miconazole eye drops in Candida albicans-induced keratomycosis.

    abstract:PURPOSE:Extemporaneously prepared miconazole eye drops (EPMD) are used by some eye care practitioners to manage keratomycosis in Ghana. This study therefore aimed to determine the efficacy and safety of EPMD using in vitro and in vivo experimental models. METHODS:The minimum inhibitory concentration (MIC) of EPMD was ...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-017-0707-z

    authors: Gyanfosu L,Koffuor GA,Kyei S,Ababio-Danso B,Peprah-Donkor K,Nyansah WB,Asare F

    更新日期:2018-10-01 00:00:00

  • The Nd:YAG laser 1.3 u wavelength: in vitro effects on ocular structures.

    abstract::We evaluated the in vitro effects of the 1.3 u wavelength of a Nd:YAG laser using a fiberoptic delivery system, with or without sapphire tips on ocular tissue. Conjunctival and retinal adhesions were achieved best with a noncontact technique compared with a contact method. ...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00155628

    authors: Peyman GA,Katoh N,Desai A

    更新日期:1987-08-01 00:00:00

  • Hypopyon--an unusual sign in acute angle-closure glaucoma.

    abstract::The appearance of a hypopyon is an extremely uncommon finding in acute angle-closure glaucoma and only a few cases have been previously reported in the literature. We report a fifty-year-old female who, following a recent bereavement, presented with classical features of acute angle-closure glaucoma and a hypopyon. Th...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00942925

    authors: Au Eong KG,Chua EC,Yip CC,Tun Y,Lim AS

    更新日期:1993-06-01 00:00:00

  • Comparison of inflammatory cytokines levels in the aqueous humor with diabetic retinopathy.

    abstract:PURPOSE:Evidence has accumulated suggesting that various inflammatory cytokines are involved in the progress of diabetic retinopathy (DR), but there are few studies concerning the relationship between individual cytokines levels in the aqueous humor (AH) and the severity of DR. This study aimed to explore the differenc...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01463-9

    authors: Zhang H,Liang L,Huang R,Wu P,He L

    更新日期:2020-10-01 00:00:00

  • Comparison of the efficacy of accelerated corneal cross-linking therapy in different pediatric age groups having progressive keratoconus.

    abstract:PURPOSE:To report a comparison analysis of accelerated corneal cross-linking (A-CXL) treatment for progressive keratoconus patients in different pediatric age groups. STUDY DESIGN:Retrospective, cross-sectional. METHODS:Patients with progressive keratoconus aged ≤ 18 were retrospectively reviewed. Forty-one eyes of 4...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01446-w

    authors: Ozer MD,Batur M,Mesen S,Tekın S,Seven E,Yasar T

    更新日期:2020-10-01 00:00:00

  • Evaluation of the learning curve of non-penetrating glaucoma surgery.

    abstract:PURPOSE:To evaluate the learning curve of non-penetrating glaucoma surgery (NPGS). METHODS:The study included 32 eyes of 27 patients' (20 male and 7 female) with medically uncontrolled glaucoma. Non-penetrating glaucoma surgeries performed by trainees under control of an experienced surgeon between 2005 and 2007 at ou...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-017-0691-3

    authors: Aslan F,Yuce B,Oztas Z,Ates H

    更新日期:2018-10-01 00:00:00

  • Evaluation of the effect of combined intravitreal ranibizumab injection and sub-tenon steroid injection in the treatment of resistant diabetic macular edema.

    abstract:PURPOSE:To compare sub-tenon steroid plus anti-VEGF injection with anti-VEGF injection solely in the treatment of resistant diabetic macular edema (DME). METHOD:Patients who exhibited insufficient anatomic [over 350 μm central macular thickness (CMT)] and less than 3 lines of visual gain at least six anti-VEGF injecti...

    journal_title:International ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10792-018-0977-0

    authors: Eriş E,Perente I,Vural E,Vural A,Seymen Z,Celebi ARC,Erdogan G,Ozkaya A,Artunay O

    更新日期:2019-07-01 00:00:00

  • Peripapillary vessel density in pediatric cases with buried optic disk drusen.

    abstract:BACKGROUND:To evaluate the retinal nerve fiber layer (RNFL) and peripapillary vascular density (VD) changes in the pediatric group with optic disk drusen (ODD). METHODS:Sixty eyes of 30 patients with buried ODD referred by the pediatric or neurology physicians to ophthalmology clinic with a preliminary diagnosis of pa...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-021-01700-9

    authors: Türker IÇ,Doğan CU,Uzun SÜ,Güven D

    更新日期:2021-01-18 00:00:00