Baseline demographics, clinical features, and treatment protocols of 240 patients with optic neuropathy: experiences from a neuro-ophthalmological clinic in the Aegean region of Turkey.

Abstract:

PURPOSE:To analyze the demographic patterns, clinical characteristics, and treatment protocols of optic neuropathies. MATERIALS AND METHODS:The hospital data of patients with optic neuropathy admitted to the Department of Neuro-ophthalmology in a tertiary referral center in Turkey between January 2010 to January 2017 were retrospectively analyzed. Demographic patterns, clinical features, treatment protocols, and the natural disease courses were assessed. RESULTS:The total number of patients with optic neuropathy seen over this period was 240, which consist of 43 with idiopathic optic neuritis (17.9%), 40 with multiple sclerosis-related optic neuritis (16.7%), 12 with chronic relapsing inflammatory optic neuritis (5.0%), 12 with atypical optic neuritis (5.0%), 11 with neuromyelitis optica spectrum disorders-related optic neuritis (4.6%), 90 with non-arteritic ischemic optic neuropathy (37.5%), 4 with arteritic ischemic optic neuropathy (1.7%), 10 with traumatic optic neuropathy (4.1%), 6 with compressive optic neuropathy (2.5%), and 12 with mitochondrial optic neuropathy [9 with toxic optic neuropathy (3.7%) and 3 with Leber's hereditary optic neuropathy (1.2%)]. There were 101 males (42%) and 139 females (58%). The mean age was 43.34 ± 15.86 years. CONCLUSION:This study reported the demographics, clinical characteristics, and treatment protocols of optic neuropathies in a neuro-ophthalmology specialty clinic at a tertiary referral center in Turkey during the past decade. The data may be useful in assessing the global status of optic neuropathies.

journal_name

Int Ophthalmol

authors

Karti O,Karti DT,Kilic İH,Gokcay F,Celebisoy N

doi

10.1007/s10792-017-0799-5

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

155-166

issue

1

eissn

0165-5701

issn

1573-2630

pii

10.1007/s10792-017-0799-5

journal_volume

39

pub_type

杂志文章
  • Pediatric keratoconus: a review of the literature.

    abstract:PURPOSE:To describe the epidemiology and prevalence, rates of progression, difference between adult and pediatric populations, and therapeutic approaches to pediatric keratoconus from documented literature. METHODS:A literature search was done on PubMed using key words including pediatric keratoconus, children with ke...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-017-0699-8

    authors: Mukhtar S,Ambati BK

    更新日期:2018-10-01 00:00:00

  • 5-Fluorouracil versus mitomycin C as adjuncts to conjunctival autograft in preventing pterygium recurrence.

    abstract::To compare the efficacy of 5-fluorouracil (5-FU) with mitomycin C (MMC) in preventing pterygium recurrence when used as an adjuvant following pterygium excision with conjunctival autograft. Low-dose MMC combined with conjunctival autograft is an effective treatment for preventing recurrence following pterygium excisio...

    journal_title:International ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10792-011-9509-x

    authors: Bekibele CO,Ashaye A,Olusanya B,Baiyeroju A,Fasina O,Ibrahim AO,Ogun O

    更新日期:2012-02-01 00:00:00

  • Combined central retinal artery-central vein obstruction.

    abstract::The cases of 23 patients with unilateral combined central retinal artery-central retinal vein obstruction are described. Criteria for the abnormality included: a history of relatively sudden visual loss; superficial retinal whitening in the posterior pole in combination with a cherry spot; and intraretinal blood, gene...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00918861

    authors: Brown GC,Duker JS,Lehman R,Eagle RC Jr

    更新日期:1993-02-01 00:00:00

  • Visual acuity and corneal higher-order aberrations after EX-PRESS or trabeculectomy, and the determination of associated factors that influence visual function.

    abstract:PURPOSE:This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy. METHODS:Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations ...

    journal_title:International ophthalmology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10792-017-0685-1

    authors: Kobayashi N,Hirooka K,Nitta E,Ukegawa K,Tsujikawa A

    更新日期:2018-10-01 00:00:00

  • The technique and indications for photocoagulation in diabetic retinopathy. I. Principles of photocoagulation.

    abstract::The beneficial effect of photocoagulation in diabetic retinopathy is now established (2-6, 10). Whereas the capability of providing photocoagulation is widespread, the indications and actual techniques are poorly defined. In this paper, we propose to discuss the principles of photocoagulation. In a following paper the...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00133274

    authors: Blach R,Hamilton AM

    更新日期:1978-09-01 00:00:00

  • Incidence and clinical presentation of chlamydial keratoconjunctivitis: a preliminary study.

    abstract::Using a direct immunofluorescent technique and monoclonal antibody, chlamydia trachomatis was detected in the conjunctival smears of 13 out of 47 patients presenting with conjunctivitis or keratoconjunctivitis (an incidence of 28%). Two patients presented with acute symptoms of few days duration, whereas the condition...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00133933

    authors: Coppens I,Abu el-Asrar AM,Maudgal PC,Missotten L

    更新日期:1988-01-01 00:00:00

  • Retinal toxicity of indocyanine green.

    abstract:PURPOSE:To describe a case of scattered toxicity of indocyanine green on the outer retina and retinal pigment epithelium (RPE) after indocyanine green (ICG) assisted membrane peeling for macular pucker. METHODS:A 61-year-old woman was examined by slit-lamp biomicroscopy, fluorescein angiography (FA), indocyanine green...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-007-9112-3

    authors: Querques G,Prascina F,Iaculli C,Noci ND

    更新日期:2008-04-01 00:00:00

  • Occurrence of cholinergic nerve fibers in the human uveoscleral tissue.

    abstract::We have studied the cholinergic nerve fibers (CNF) of human uveoscleral tissue in normal and pathological conditions (intraocular pressure: (IOP) of various degrees ) and have performed a quantitative image analysis of CNF with the aim of studying an hypothetical association between IOP and the uveoscleral level of ch...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1023/a:1006306812296

    authors: Cavallotti C,Pescosolido N,Leali FM,Gherardi F,Cavallotti D

    更新日期:1998-01-01 00:00:00

  • Bilateral visual loss with eosinophilic infiltration in the bone marrow and the retina.

    abstract::A young patient is described who presented with sudden visual loss in the left eye quickly followed by proliferative retinopathy with retinal detachment and thrombotic glaucoma. He developed similar initial symptoms in the right eye but has now made a complete recovery in that eye on systemic steroids, oral acyclovir,...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00163567

    authors: Woon HW,Graham EM

    更新日期:1990-10-01 00:00:00

  • Regional comparison of preoperative biometry for cataract surgery between two domestic institutions.

    abstract:PURPOSE:Regional variations of the preoperative biometry can affect the refractive accuracy of cataract surgery. We aimed to compare the preoperative biometric data for cataract surgery between two domestic institutions. METHODS:We retrospectively reviewed the preoperative biometric data of 673 consecutive eyes underg...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01476-4

    authors: Kamiya K,Fujimura F,Iijima K,Nobuyuki S,Mori Y,Miyata K

    更新日期:2020-11-01 00:00:00

  • Quantitative assessment of the effect of acute anaerobic exercise on macular perfusion via swept-source optical coherence tomography angiography in young football players.

    abstract:AIM:To evaluate the effect of acute anaerobic exercise on macular perfusion measured by swept-source optical coherence tomography angiography (SS-OCTA) in young football players. MATERIALS AND METHODS:Football players with ages between 18 and 20 years were included into the study. After a detailed ophthalmological exa...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01303-w

    authors: Karakucuk Y,Okudan N,Bozkurt B,Belviranlı M,Sezer T,Gorçuyeva S

    更新日期:2020-06-01 00:00:00

  • Physiological diurnal variability and characteristics of the ocular pulse amplitude (OPA) with the dynamic contour tonometer (DCT-Pascal).

    abstract:PURPOSE:The Pascal dynamic contour tonometer (DCT) allows measurement of intraocular pressure (IOP) independently of corneal properties. It records, simultaneously, haemodynamic IOP fluctuations and the difference between the systolic and the diastolic IOP corresponding to the ocular pulse amplitude (OPA). The OPA indi...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-007-9161-7

    authors: Pourjavan S,Boëlle PY,Detry-Morel M,De Potter P

    更新日期:2007-12-01 00:00:00

  • Efficacy of single-dose dexamethasone implantation in patients with persistent diabetic macular edema.

    abstract::To investigate the efficacy of single-dose intravitreal dexamethasone implantation in the treatment of persistent diabetic macular edema (DME) unresponsive to 3 consecutive ranibizumab injections over a period of 6 months. Forty-one patients with a previous history of treatment for DME including at least three consecu...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-015-0155-6

    authors: Arıkan Yorgun M,Toklu Y,Mutlu M,Uysal BS,Çakmak HB

    更新日期:2016-08-01 00:00:00

  • Safety and efficacy of bilateral simultaneous XEN implant surgery: a pilot study.

    abstract:OBJECTIVE:To evaluate the efficacy and safety of the bilateral simultaneous XEN (BISIXEN) surgery in open-angle glaucoma patients. METHODS:Retrospective analysis of a prospective data base conducted on uncontrolled glaucoma patients who underwent BISIXEN surgery. Primary endpoint measure was the incidence of sight-thr...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01640-w

    authors: Urcola A,Garay-Aramburu G

    更新日期:2021-01-02 00:00:00

  • Outcomes of same-site re-operation with minimal use of mitomycin in failed trabeculectomy.

    abstract::To evaluate efficacy and safety of same site re-operation in eyes with failed trabeculectomy. A retrospective, noncomparative, interventional case series. We reviewed the medical records of 35 eyes of 35 patients who underwent same-site re-operation for failed trabeculectomy. The surgery involved a fornix-based perito...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-013-9840-5

    authors: Eslami Y,Samarai V,Mohammadi M,Fakhraie G,Zarei R,Eslami S,Moghimi S

    更新日期:2014-06-01 00:00:00

  • Graft failure: III. Glaucoma escalation after penetrating keratoplasty.

    abstract::Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus ...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/s10792-008-9223-5

    authors: Greenlee EC,Kwon YH

    更新日期:2008-06-01 00:00:00

  • Oximetry with a multiple wavelength SLO.

    abstract::Oximetry may be useful for understanding pathologies of the eye. We use a prototype scanning laser ophthalmoscope capable of simultaneous multiple wavelength imaging to record fundus images. The system is run under non-confocal conditions in using slit apertures with a width of up to 600 microm. The laser lines launch...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1023/a:1014406831412

    authors: Ashman RA,Reinholz F,Eikelboom RH

    更新日期:2001-01-01 00:00:00

  • Outcome of intravitreal dexamethasone implant for the treatment of ranibizumab-resistant macular edema secondary to retinal vein occlusion.

    abstract::To assess the effect of intravitreal dexamethasone implant (Ozurdex) for the treatment of macular edema secondary to retinal vein occlusion (RVO) resistant to repeated intravitreal ranibizumab injection. Retrospective review of 11 patients (11 eyes) with ranibizumab-resistant macular edema secondary to RVO. Macular ed...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-016-0226-3

    authors: Manousaridis K,Peter S,Mennel S

    更新日期:2017-02-01 00:00:00

  • Evaluation of the outcome of long-tube shunt implant surgery in uveitic glaucoma patients by analyzing the background of uveitis.

    abstract:PURPOSE:To evaluate the efficacy of long-tube shunt surgery (LTSS) without valve in uveitic glaucoma (UG) eyes. METHODS:We retrospectively analyzed the data of 45 UG eyes that underwent only LTSS or LTSS combined with trabeculectomy (TLE) (LTSS/TLE). The UG eyes were analyzed by categorizing them into granulomatous/no...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01601-3

    authors: Watanabe S,Hamanaka T,Sakurai T,Kobayashi K,Ishida N,Ebihara N

    更新日期:2020-10-14 00:00:00

  • Tear ferning and other lacrimal tests in normal persons of different ages.

    abstract::We investigated in normal persons of different ages ranging from 4 months to 85 years the frequency of different ferning types as well as the results of the Schirmer I test, break-up time and tear protein profile. With increasing age, ferning types of higher degree were significantly more frequent. Furthermore, a corr...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00137950

    authors: Puderbach S,Stolze HH

    更新日期:1991-11-01 00:00:00

  • Gyrate atrophy of the choroid and retina. Approaches to therapy.

    abstract::Gyrate atrophy of the choroid and retina is caused by deficient activity of ornithine ketoacid aminotransferase, a pyridoxal phosphate dependent enzyme. Besides the typical eye findings, abnormalities have been found on muscle biopsy, electro-encephalography, electromyography and electrocardiography, establishing this...

    journal_title:International ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1007/BF00139577

    authors: Weleber RG,Kennaway NG,Buist NR

    更新日期:1981-08-01 00:00:00

  • An international classification of retinopathy of prematurity.

    abstract::The unifying principle underlying this classification system is: The more posterior the disease and the greater the amount of involved retinal vascular tissue, the more serious the disease. The staging of the disease at any given location expresses the natural history and evolution of events at the border between vasc...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00136454

    authors:

    更新日期:1985-04-01 00:00:00

  • Vitreous albumin redox state in open-angle glaucoma patients and controls: a pilot study.

    abstract:PURPOSE:Numerous studies suggest that reactive oxygen species play a crucial role in the development of glaucoma. Since glaucoma patients exhibit posterior vitreous detachment earlier than controls, it has been suggested that reactive oxygen species-increased in glaucoma-also affect the vitreous. In the present study w...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-019-01268-5

    authors: Schwab C,Paar M,Fengler VH,Lindner E,Haas A,Ivastinovic D,Seidel G,Weger M,Wedrich A,Oettl K

    更新日期:2020-04-01 00:00:00

  • Outcome of cataract surgery by a general medical doctor at district level, Zimbabwe: a retrospective follow-up study.

    abstract::From January 1990 until October 1992, 103 Zimbabwean patients underwent intracapsular cataract extraction by a general medical doctor. Of the first 100 patients operated upon, 50 were traced of which 37 could be assessed adequately. Operative complications and visual acuities after three months show that this is an ef...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00131924

    authors: Killestein J,Hillegers M,van der Windt C,Stilma JS

    更新日期:1996-01-01 00:00:00

  • Effect of color information on the diagnostic performance of glaucoma in deep learning using few fundus images.

    abstract:PURPOSE:The purpose of this study was to evaluate the accuracy of the convolutional neural network (CNN) model in glaucoma identification with three primary colors (red, green, blue; RGB) and split color channels using fundus photographs with a small sample size. METHODS:The dataset was prepared using color fundus pho...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-020-01485-3

    authors: Hirota M,Mizota A,Mimura T,Hayashi T,Kotoku J,Sawa T,Inoue K

    更新日期:2020-11-01 00:00:00

  • Mycolase II: an enzyme antifungal agent interacts with the polyene antibiotic pimaricin in the treatment of keratomycosis.

    abstract::An animal model of keratomycosis was used to study the interaction between the new enzyme antifungal compound mycolase II and the polyene antifungal antibiotic pimaricin. Well established corneal infection caused by an ocular pathogenic candida albicans on New Zealand white male rabbits were treated with 3% mycolase I...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/BF00149150

    authors: Oji EO

    更新日期:1982-11-01 00:00:00

  • Ranibizumab versus aflibercept for the treatment of vascularized pigment epithelium detachment due to age-related macular degeneration.

    abstract:PURPOSE:To compare the efficacy and safety of two intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents, ranibizumab and aflibercept, for the treatment of vascularized pigment epithelium detachment (vPED) due to age-related macular degeneration (AMD) in a follow-up time of 12 months. METHODS:Particip...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-018-0833-2

    authors: Rouvas A,Chatziralli I,Androu A,Mpougatsou P,Alonistiotis D,Douvali M,Kabanarou SA,Theodossiadis P

    更新日期:2019-02-01 00:00:00

  • Vitreous IL-8 and VEGF levels in diabetic macular edema with or without subretinal fluid.

    abstract:PURPOSE:To determine the cytokine levels in vitreous samples of diabetic macular edema (DME) patients in comparison with nondiabetic patients, and to evaluate the effect of subretinal fluid on the cytokine levels of vitreous samples. METHODS:In this prospective case-control study, 11 eyes of 11 patients with DME and s...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-018-0874-6

    authors: Yenihayat F,Özkan B,Kasap M,Karabaş VL,Güzel N,Akpınar G,Pirhan D

    更新日期:2019-04-01 00:00:00

  • Boston keratoprosthesis restoring vision in an unusual case of end-stage limbal stem cell deficiency following exposure to Euphorbia latex.

    abstract::We report the functional outcome of a patient who had undergone Boston keratoprosthesis type I for extensive ocular surface damage caused by latex of Euphorbia. The milky sap or latex of the Euphorbia plant is highly toxic and an irritant to the skin and eye. Damage to the eye ranges from mild to severe corneal edema,...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-012-9515-7

    authors: Dutta J,Mukhopadhyay S,Datta H,Sen S

    更新日期:2012-02-01 00:00:00

  • Small-incision lenticule addition in ex vivo model of ectatic human corneas.

    abstract:PURPOSE:To investigate the feasibility of intrastromal lenticule insertion to restore corneal shape in a model of ectatic human cornea. METHODS:For this experimental ex vivo study on 34 human corneas unsuitable for transplantation, 17 corneas were thinned by decentralized posterior excimer laser ablation to 200 μm thi...

    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-019-01106-8

    authors: Pedrotti E,Cozzini T,Fasolo A,Bonacci E,Bonetto J,Merz T,Talli P,Marchini G

    更新日期:2019-11-01 00:00:00