Abstract:
:An animal model of keratomycosis was used to study the interaction between the new enzyme antifungal compound mycolase II and the polyene antifungal antibiotic pimaricin. Well established corneal infection caused by an ocular pathogenic candida albicans on New Zealand white male rabbits were treated with 3% mycolase II, 5% pimaricin and a combination of 3% mycolase II and 5% pimaricin respectively. The rates of resolution of the corneal lesions for each group of eyes treated by the various drugs were determined and the results were analysed by computer using a two-way analysis of variance to determine the interaction or independence of 3% mycolase II in combination therapy with 5% pimaricin in rabbit keratomycosis. The analysis of variance showed a significant level of positive interaction after each period of treatment. (P less than 0.001).
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Oji EOdoi
10.1007/BF00149150subject
Has Abstractpub_date
1982-11-01 00:00:00pages
175-9issue
3eissn
0165-5701issn
1573-2630journal_volume
5pub_type
杂志文章abstract::This paper presents 5 patients seen in the Eye Clinic, Royal Victoria Hospital, Belfast with orbital infiltration of malignant eyelid tumours. The physical features and natural progression of the disease are described. The value of CT scans in determining the extent of the disease and patient management are described....
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00159865
更新日期:1990-07-01 00:00:00
abstract:PURPOSE:To report a childhood case of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) carrying the R92Q variant with a vision-threatening bilateral panuveitis. METHODS:Case report and review of the literature. RESULTS:A 7-year-old boy presented with an active bilateral panuveitis and a macular ras...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-017-0785-y
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:The surgical management of macular holes has been a subject of controversy in recent years. Various techniques such as vitrectomy, membrane peeling, and gas tamponade with or without transforming growth factor-beta 2, and recently the use of autologous platelets have produced closure rates from 58% to 96%, d...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1023/a:1005866002930
更新日期:1997-01-01 00:00:00
abstract::One hundred cases of clinically acceptable sympathetic ophthalmia (SO) were evaluated histologically to determine the incidence of atypical features and correlate them with the severity of choroidal inflammation. The inflammatory response in the choroid varied from a focal non-granulomatous to a diffuse non-necrotizin...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00161902
更新日期:1982-02-01 00:00:00
abstract::We describe a case illustrating a new technique of using intraoperative optical coherence tomography (IOCT) for foreign body removal from the limbus and cornea. In this case, fragments of a fish hook in the temporal limbus and cornea were identified on the OCT. The residual pieces were then removed, assisted by high-r...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0304-6
更新日期:2017-06-01 00:00:00
abstract::Glycated proteins formed by the Maillard reaction were measured by furosine determination in human normal lenses and in senile and diabetic cataracts. Furosine, an hydrolysis product of fructose-lysine adduct formed in the early stages of the Maillard reaction, was measured by high performance liquid chromatography (H...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00951795
更新日期:1994-01-01 00:00:00
abstract::To compare the efficacy of 5-fluorouracil (5-FU) with mitomycin C (MMC) in preventing pterygium recurrence when used as an adjuvant following pterygium excision with conjunctival autograft. Low-dose MMC combined with conjunctival autograft is an effective treatment for preventing recurrence following pterygium excisio...
journal_title:International ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10792-011-9509-x
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:Regional variations of the preoperative biometry can affect the refractive accuracy of cataract surgery. We aimed to compare the preoperative biometric data for cataract surgery between two domestic institutions. METHODS:We retrospectively reviewed the preoperative biometric data of 673 consecutive eyes underg...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01476-4
更新日期:2020-11-01 00:00:00
abstract::Ocular tuberculosis is difficult to diagnose but should be suspected when uveitis fails to respond to inflammation suppressive therapy. Interferon-gamma release assays (IGRAs) represent a substantial help to diagnose suspected ocular tuberculosis especially in non-endemic areas. Indocyanine green angiography (ICGA) is...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-012-9588-3
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the safety indexes and efficacy of Artisan phakic intraocular lens (IOL) for the correction of high myopia. METHODS:Retrospective interventional case series reports. Thirty-one eyes (22 patients) with myopia from -5.25 to -19.00 diopters underwent implantation of an Artisan phakic IOL. Follow-up...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-005-5016-2
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:To describe and evaluate the value of nutritional supplements in the management of age-related macular degeneration (AMD) through a review of the current literature. METHODS:An extensive literature search was performed, and key research articles exploring AREDS and AREDS-2 formulations, genetics, omega fatty a...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-019-01140-6
更新日期:2019-12-01 00:00:00
abstract::Melanoma-associated retinopathy is a paraneoplastic retinopathy associated mostly with cutaneous melanoma. In most cases it presents months to years after diagnosis of primary cutaneous melanoma was made or after recurrence. We describe a 55-year-old male patient who presented with symptoms of decreased vision and pho...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9564-y
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:To report two cases of ciliochoroidal effusion after the usage of topiramate. CASES:Two middle-aged women experienced sudden onset of acute glaucoma and acquired myopia after taking topiramate. Ultrasound biomicroscopy demonstrated bilateral ciliochoroidal effusion and angle closure. The A-scan ultrasonography...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-017-0740-y
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To evaluate whether retrobulbar blood flow and choroidal thickness (CT) are affected in patients with rheumatoid arthritis (RA), and the relationship between these values. METHODS:We evaluated 40 eyes of 20 RA patients and 40 eyes of 20 healthy controls. The enhanced depth imaging optical coherence tomography,...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0656-6
更新日期:2018-10-01 00:00:00
abstract::To describe the efficacy of intravitreal chemotherapy (IViC) preceded by intra-arterial chemotherapy (IAC) for the treatment of advanced stage retinoblastoma. This non-comparative interventional case series retrospectively reviewed the medical records of six patients who presented within months of each other with unil...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-015-0129-8
更新日期:2015-12-01 00:00:00
abstract::Current theories for macular hole formation implicate antero-posterior and tractional forces at the vitreofoveal interface. It is thought that localized perifoveal defects enlarge from centrifugal forces acting about the axis of ocular rotation. If this is true, eyes with longer axial lengths should have an increased ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9568-7
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:Numerous studies suggest that reactive oxygen species play a crucial role in the development of glaucoma. Since glaucoma patients exhibit posterior vitreous detachment earlier than controls, it has been suggested that reactive oxygen species-increased in glaucoma-also affect the vitreous. In the present study w...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01268-5
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:To describe the incidence of, and risk factors associated with, diabetic retinopathy in diabetic persons assessed at a Saudi diabetes centre. METHODS:Five hundred and two patients with diabetes mellitus assessed by our service were studied. There were 174 patients (34.7%) with insulin-dependent diabetes mellit...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1006240928938
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To elucidate the role of trabeculectomy in advanced glaucoma. MATERIALS AND METHODS:Only patients with primary open-angle glaucoma were selected. All patients who had cup-disc ratio of 0.9 or a near-total cupping were given a trial of aggressive maximum medical therapy for IOP control for at least 4 weeks. Tar...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0797-7
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to compare the macular and peripapillary capillary vessel density (CVD) and foveal avascular zone (FAZ) in amblyopic eyes of adults with their fellow eyes and with eyes of healthy controls using optical coherence tomography-angiography (OCT-A). METHODS:A total of 34 eyes of 17 pa...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01345-0
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To investigate complex and different phenotypes in seven Chinese patients diagnosed with Bardet-Biedl syndrome (BBS) and carrying pathogenic mutations. METHODS:Seven unrelated BBS patients were enrolled. Their medical and ophthalmic histories were reviewed, and comprehensive clinical examinations, such as fund...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01415-3
更新日期:2020-09-01 00:00:00
abstract:INTRODUCTION:We report on a 62-year-old healthy woman who suffered from bilateral predescemetic opacities, where the underlying disorder could not be identified. She had bilateral keratopathy with corneal edema, a diffuse predescemetic avascular haze and deszemetic folds. Because of high hyperopia (right +7.50/left +7....
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/b:inte.0000018521.88103.17
更新日期:2004-01-01 00:00:00
abstract::The aim of this study is to compare a portable spectral domain optical coherence tomography (SD-OCT) device with a non-portable SD-OCT for the identification of anterior chamber angle parameters based on location of Schwalbe's line (SL) and to measure their reproducibility. 99 eyes from 46 normal, healthy participants...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0223-6
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:To assess safety and efficacy of deep topical anesthesia with ropivacaine-soaked sponge compared with topical anesthesia with oxybuprocaine in patients undergoing phacoemulsification. METHODS:This was a retrospective study where records of patients operated for cataract were evaluated. Patients using a visual ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01132-6
更新日期:2019-12-01 00:00:00
abstract::To evaluate the effect of intravitreal bevacizumab (IVB) before Ahmed valve implantation for treatment of neovascular glaucoma (NVG). This study is a retrospective, comparative, consecutive case series. The study group consisted of 27 eyes of 26 patients with NVG who underwent an Ahmed valve implantation. Thirteen eye...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9875-7
更新日期:2014-08-01 00:00:00
abstract::Retinal astrocytic hamartomas are benign tumors of the retinal nerve fiber layer (NFL) that may be found in association with tuberous sclerosis (TS). We describe the spectral-domain optical coherence tomography (SD-OCT) features of type 1 astrocytic hamartomas in a child with TS that may aid in the diagnosis and follo...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9586-5
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To compare the outcome of penetrating keratoplasty (PKP) and deep anterior lamellar keratoplasty (DALK) in the surgical management of keratoconus (KC). PATIENT AND METHODS:A retrospective review was conducted of the medical records of all patients treated with PKP or DALK for KC at University of Iowa Hospitals...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-010-9393-9
更新日期:2010-12-01 00:00:00
abstract::Insulin-like growth factor-1 (IGF-1) is altered in several neurodegenerative diseases, the association between serum IGF-1 levels and glaucoma has not been evaluated. This study was designed to evaluate whether serum IGF-1 levels are different in patients with Pseudoexfoliation (PEX) with or without glaucoma. The stud...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0271-y
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To determine the cytokine levels in vitreous samples of diabetic macular edema (DME) patients in comparison with nondiabetic patients, and to evaluate the effect of subretinal fluid on the cytokine levels of vitreous samples. METHODS:In this prospective case-control study, 11 eyes of 11 patients with DME and s...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0874-6
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:We evaluated the ability of optic disc parameters and nerve fiber analysis with the Glaucoma-scope to distinguish glaucoma from normal or hypertensive eyes. METHODS:Glaucoma-scope examination was performed on 68 eyes of 44 patients split into following groups based on Humphrey 24-2 visual field and clinical cr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00212942
更新日期:1996-01-01 00:00:00