Abstract:
:Glycated proteins formed by the Maillard reaction were measured by furosine determination in human normal lenses and in senile and diabetic cataracts. Furosine, an hydrolysis product of fructose-lysine adduct formed in the early stages of the Maillard reaction, was measured by high performance liquid chromatography (HPLC). Furosine levels in diabetic cataracts were found to be 3 to 4 times higher than those observed for senile cataracts. The increased glycation levels both in cortex and nucleus were related to the increase of fluorescence determined in vitro by fluorometry and in vivo by Scheimpflug photography. Lens proteins were incubated with glucose and it has been demonstrated that protein glycation occurred parallel with the increase in concentration of fluorescent chromophores that present similar characteristics as those observed in vivo. The results indicate that protein insolubilization seemed to involve preferentially glycated proteins and at least in diabetic cataracts, the process seems to be initiated in the cortical region.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Mota MC,Carvalho P,Ramalho JS,Cardoso E,Gaspar AM,Abreu Gdoi
10.1007/BF00951795subject
Has Abstractpub_date
1994-01-01 00:00:00pages
187-93issue
4eissn
0165-5701issn
1573-2630journal_volume
18pub_type
杂志文章abstract:PURPOSE:To assess the level of awareness among UK ophthalmic surgeons of the potential risks from starch powdered surgical gloves during ophthalmic surgery and to show by electron microscopy that starch granule contamination can occur during ophthalmic surgery. SETTING:A sample (N = 46) of UK ophthalmologists from the...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1006392915801
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:Proliferative vitreoretinopathy (PVR) is characterized by the formation of cellular membranes on the detached retina and also in the vitreous. Glial cells can be found in epiretinal and subretinal membranes from eyes with PVR, proliferative diabetic retinopathy (PDR), idiopathic macular pucker, uveitis and othe...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1022509614815
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To evaluate the cognitive performance of patients with glaucoma and compare it to individuals with Alzheimer's disease (AD). METHODS:This is a prospective, cross-sectional and case-control study. All subjects were assessed using the Mini-Mental State Examination (MMSE) and its subtests verbal fluency, word lis...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0658-4
更新日期:2018-10-01 00:00:00
abstract::We describe a case illustrating a new technique of using intraoperative optical coherence tomography (IOCT) for foreign body removal from the limbus and cornea. In this case, fragments of a fish hook in the temporal limbus and cornea were identified on the OCT. The residual pieces were then removed, assisted by high-r...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0304-6
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION:We report on a 62-year-old healthy woman who suffered from bilateral predescemetic opacities, where the underlying disorder could not be identified. She had bilateral keratopathy with corneal edema, a diffuse predescemetic avascular haze and deszemetic folds. Because of high hyperopia (right +7.50/left +7....
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/b:inte.0000018521.88103.17
更新日期:2004-01-01 00:00:00
abstract::Oximetry may be useful for understanding pathologies of the eye. We use a prototype scanning laser ophthalmoscope capable of simultaneous multiple wavelength imaging to record fundus images. The system is run under non-confocal conditions in using slit apertures with a width of up to 600 microm. The laser lines launch...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1014406831412
更新日期:2001-01-01 00:00:00
abstract::Central serous chorioretinopathy (CSCR) is characterized by neurosensory retinal detachment. Because the retina pigment epithelium and choroidal pathology is the current mechanism in CSCR, many studies in the literature focused on the outer retinal layers. There is little information about the functional or histologic...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0278-4
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To compare corneal graft survival rates after penetrating keratoplasty (PK) and Descemet's stripping endothelial keratoplasty (DSEK) in patients with a glaucoma drainage device (GDD) or medically managed glaucoma. METHODS:A retrospective chart review was conducted on consecutive patients who underwent primary ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0451-4
更新日期:2018-02-01 00:00:00
abstract::To evaluate the potential benefit of intraocular pressure (IOP) reduction in normal-tension glaucoma (NTG) patients in South Korea. A retrospective, multi-center analysis of Korean NTG patients with 5-years follow-up, typical glaucomatous optic disc and/or visual field changes and no recorded IOP >21 mmHg. Progression...
journal_title:International ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10792-011-9463-7
更新日期:2011-10-01 00:00:00
abstract::The physiology of the orbital arteries supplying the eye is currently under intensive investigation. However, while the anatomical distribution of these vessels in humans is well known, their normal histology and age-related or other pathologic alterations have hardly been studied. We obtained at autopsy 10 orbits fro...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00918866
更新日期:1993-02-01 00:00:00
abstract::The cases of 23 patients with unilateral combined central retinal artery-central retinal vein obstruction are described. Criteria for the abnormality included: a history of relatively sudden visual loss; superficial retinal whitening in the posterior pole in combination with a cherry spot; and intraretinal blood, gene...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00918861
更新日期:1993-02-01 00:00:00
abstract::To evaluate the efficacy of 25-ga pars plana vitrectomy (PPV) and 25-ga PPV combined with phacoemulsification surgery for managing ciliary block (malignant) glaucoma. The medical records of 11 eyes, in nine consecutive patients with malignant glaucoma were retrospectively reviewed to determine the efficacy of 25-ga PP...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-014-9974-0
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:To evaluate the influence of strong fixation preference on clinical and surgical outcomes, in non-amblyopic patients with basic-type intermittent exotropia (IXT). MATERIALS AND METHODS:The records of patients were retrospectively investigated. Non-amblyopic patients with the diagnosis of basic-type IXT were en...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01603-1
更新日期:2020-10-14 00:00:00
abstract:PURPOSE:To investigate the characteristics of dynamic visual acuity (DVA) and contrast sensitivity (CS) in pseudophakic patients with posterior capsular opacification (PCO). METHODS:Fifty-four eyes (36 patients) with PCO planned for laser capsulotomy were recruited. They underwent examinations of static visual acuity ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01536-9
更新日期:2020-12-01 00:00:00
abstract::A case of keratomycosis caused by Alternaria species in a patient with glaucoma is reported. A 55-year-old Japanese man who had been followed for developmental glaucoma presented with corneal ulcer in his right eye, which did not respond to antibacterial agents. There was no history of traumatic episode. Culture on po...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9260-0
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the use of Optical Coherence Tomography (OCT) in the diagnosis of macular edema (ME) in diabetic patients in comparison to indirect ophthalmoscopy (IO) and, in addition, to study the characteristics of these patients. METHODS:165 patients were randomly selected to join the study in 1998. Ophthal...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/b:inte.0000006784.52885.e9
更新日期:2001-01-01 00:00:00
abstract::To describe the epidemiology, mechanism of injury, and final visual and anatomical outcomes of pediatric patients with open globe injury. The medical records of patients aged ≤ 16 years diagnosed with open globe injury between January 2006 and December 2010 were retrospectively reviewed. Forty-nine pediatric patients ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9890-8
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To describe indocyanine green angiography (ICGA) and visual acuity (VA) results in patients with neovascular age-related macular degeneration (nAMD) refractory to ranibizumab switched to aflibercept. METHODS:This study is a prospective interventional case series. Thirty-two eyes of 32 patients with nAMD showin...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01082-z
更新日期:2019-11-01 00:00:00
abstract::Infrequently, vitreomacular traction is released through the spontaneous development of complete posterior vitreous detachment (PVD). PVD caused by laser photocoagulation has also been reported. A 62-year-old woman with ischemic branch retinal vein occlusion showed decreased vision in the affected eye due to vitreomac...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9166-2
更新日期:2009-02-01 00:00:00
abstract:PURPOSE:To describe a case of scattered toxicity of indocyanine green on the outer retina and retinal pigment epithelium (RPE) after indocyanine green (ICG) assisted membrane peeling for macular pucker. METHODS:A 61-year-old woman was examined by slit-lamp biomicroscopy, fluorescein angiography (FA), indocyanine green...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9112-3
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:To investigate risk factors for choroidal detachment after trabeculectomy. METHODS:We prospectively evaluated 97 patients with open-angle glaucoma who underwent primary trabeculectomy to investigate risk factors for choroidal detachment after trabeculectomy. The primary outcome measure was risk factors for the...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01267-6
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To identify risk factors for endogenous endophthalmitis (EE) in hospitalized adults, under 65 years of age, with a history of intravenous opioid use and non-ocular infection. METHODS:The National Inpatient Sample Database was used to identify cases of EE with a recent history of intravenous opioid use disorder...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-021-01709-0
更新日期:2021-01-27 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the corneal biomechanical parameters in patients with ankylosing spondylitis (AS) and to compare them with the healthy subjects. METHODS:Sixty patients with AS (study group) and 60 healthy subjects (control group) were enrolled in this prospective study. The study group wa...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0368-3
更新日期:2017-08-01 00:00:00
abstract::Primary lacrimal sac melanoma is an extremely rare clinical entity with fewer than 25 cases reported in the literature. We present a well-documented case of lacrimal sac melanoma with anterior lacrimal crest infiltration and discuss the clinical, radiological and histopathological features along with surgical challeng...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9743-5
更新日期:2014-02-01 00:00:00
abstract::Dear editor and readers, this letter is written to make you aware that the original version of this article unfortunately contained a mistake. ...
journal_title:International ophthalmology
pub_type: 杂志文章,已发布勘误
doi:10.1007/s10792-018-0981-4
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To evaluate superficial capillary plexus (SCP) changes occurring after internal limiting membrane (ILM) peeling for the treatment of idiopathic epiretinal membrane (ERM). METHODS:A total of 15 eyes of 15 patients affected by idiopathic ERM (eight males and seven females; mean age 59.8 ± 9.6 years) were enrolle...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0608-1
更新日期:2018-08-01 00:00:00
abstract::To report an unusual case of primary paranasal sinus lymphoma associated with intraocular secondary uveal involvement. Retrospective case report emphasizing the histopathologic diagnosis as well as imaging studies, and review of the pertinent literature. The diagnosis of ophthalmologic lymphoma can be difficult due to...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-012-9570-0
更新日期:2012-08-01 00:00:00
abstract::The association between HLA-A29 and birdshot chorioretinopathy is the strongest of all associations between HLA and disease. Determination of HLA-A29 is even of diagnostic significance. The association between HLA-B27 and acute anterior uveitis (AAU) is much weaker, but B27 positive AAU may be considered as a distinct...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/BF00163552
更新日期:1990-10-01 00:00:00
abstract:PURPOSE:This study aims to evaluate the efficacy and safety of XEN45 gel stent (Allergan plc, Dublin, Ireland) in East Asian patients with glaucoma. METHODS:A retrospective study of consecutive XEN45 gel stent implantation surgeries with or without concurrent cataract surgery from May 2017 to August 2018 was performed...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01284-w
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To report a case of Pseudomonas aeruginosa endophthalmitis with choroidal abscess formation in a patient with bronchiectasis. METHODS:Case report. RESULTS:A 75-year-old gentleman with bronchiectasis and P. aeruginosa pneumonia developed painless loss of right eye vision. The patient had previously undergone b...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9126-x
更新日期:2008-08-01 00:00:00