Abstract：
PURPOSE:To describe the incidence of, and risk factors associated with, diabetic retinopathy in diabetic persons assessed at a Saudi diabetes centre. METHODS:Five hundred and two patients with diabetes mellitus assessed by our service were studied. There were 174 patients (34.7%) with insulin-dependent diabetes mellitus (IDDM) and 328 patients (65.3%) with non-insulin-dependent diabetes mellitus (NIDDM). RESULTS:The incidence of retinopathy was 157/502 (31.3%). The incidence was 42.5% in patients with IDDM and 25.3% in those with NIDDM. By logistic regression analysis, it was shown that old age (>60 years), insulin use, long duration of diabetes (>10 years), poor diabetes control, and the presence of nephropathy were significantly associated with the incidence of retinopathy. On the basis of the magnitudes of the regression coefficients in the hazard function, long duration of diabetes was the most important independent risk factor for the development of retinopathy; the presence of nephropathy, age >60 years, poor diabetes control, and use of insulin were less important (regression coefficients: 1.9, 1.71, 1.331, 0.8508 and 0.6178, respectively). The incidence of macular oedema was significantly associated with the presence of hypertension and high cholesterol levels in patients with IDDM. Polycotomous regression analysis showed that the presence of nephropathy was the only factor significantly associated with the severity of retinopathy. CONCLUSIONS:The significant associations with poor control and duration of diabetes provide further strong evidence for the benefits of optimal glycaemic control. Other potentially modifiable risk factors for retinopathy may be important, including elevated blood pressure and serum cholesterol.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
El-Asrar AM,Al-Rubeaan KA,Al-Amro SA,Kangave D,Moharram OAdoi
10.1023/a:1006240928938subject
Has Abstractpub_date
1998-01-01 00:00:00pages
155-61issue
3eissn
0165-5701issn
1573-2630journal_volume
22pub_type
杂志文章abstract：:This study aimed to monitor the graft-host junction's (GHJ's) apposition with anterior segment optical coherence tomogram after penetrating keratoplasty (PK) and correlate the analysis with the preoperative diagnosis. Fifty-one eyes of 50 patients with various preoperative diagnosis of adherent leucoma, pseudophakic b...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0269-5
更新日期：2017-04-01 00:00:00
abstract：:The purpose of this study was to investigate the reproducibility of choroidal thickness measurements in normal subjects on 3 spectral domain optical coherence tomography instruments, namely: Zeiss Cirrus HD-OCT (Carl Zeiss Meditec Inc., Dublin, CA), Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany), ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0306-4
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Autoenucleation is a severe, rare form of self-mutilation. The majority of cases have been reported in the 15- to 60-year age group, usually in psychiatric patients with a history of depression or schizophrenia, sometimes caused by drug abuse. CASE REPORT:We report a case of left-sided autoenucleation in an...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9222-6
更新日期：2009-08-01 00:00:00
abstract：:The unifying principle underlying this classification system is: The more posterior the disease and the greater the amount of involved retinal vascular tissue, the more serious the disease. The staging of the disease at any given location expresses the natural history and evolution of events at the border between vasc...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136454
更新日期：1985-04-01 00:00:00
abstract：:To investigate the efficacy of single-dose intravitreal dexamethasone implantation in the treatment of persistent diabetic macular edema (DME) unresponsive to 3 consecutive ranibizumab injections over a period of 6 months. Forty-one patients with a previous history of treatment for DME including at least three consecu...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0155-6
更新日期：2016-08-01 00:00:00
abstract：PURPOSE:Growth factors are considered as key molecules that participating in fibrosis formation. This research aimed to clarify potential effects of p53 on regulation of transforming growth factor β (TGF-β) and fibrosis formation and investigate the associated mechanisms. METHODS:Vimentin was examined to identify huma...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01320-9
更新日期：2020-06-01 00:00:00
abstract：:The clinical and histopathological findings are described in a case of cerebral and ocular abnormalities associated with (congenital) muscular dystrophy. Histopathological examination of the eyes revealed a fetal configuration of the anterior chamber angle, elongated ciliary processes, cataract, persistence of primary...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF01007744
更新日期：1993-08-01 00:00:00
abstract：:An animal model of keratomycosis was used to study the interaction between the new enzyme antifungal compound mycolase II and the polyene antifungal antibiotic pimaricin. Well established corneal infection caused by an ocular pathogenic candida albicans on New Zealand white male rabbits were treated with 3% mycolase I...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00149150
更新日期：1982-11-01 00:00:00
abstract：:A 37 year old woman presented with a bilateral vitritis. 4 months previously, she had developed in her left eye a necrotizing retinitis compatible with acute retinal necrosis (ARN). A trial of Acyclovir was unsuccessful as were systemic steroids. Over the following 2 months the vitritis worsened. The patient underwent...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00163568
更新日期：1990-10-01 00:00:00
abstract：PURPOSE:To compare the visual and refractive outcomes after FEMTOLASIK with and without iris registration. METHODS:In this randomized, prospective, comparative, contralateral eye study, 118 eyes of 59 patients with myopia and myopic astigmatism underwent LASIK using the Femto LDV femtosecond laser (160 µm) and the MEL...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-017-0703-3
更新日期：2018-10-01 00:00:00
abstract：:Onchocerciasis is a devastating blinding disease caused by the parasite Onchocerca volvulus that infects about 80 million people, causing blindness and visual impairment in 1-2 million people. In hyperendemic areas, more than half of the population will become blind from onchocerciasis before they die. Blindness is th...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00158317
更新日期：1990-05-01 00:00:00
abstract：:To evaluate the efficacy of 25-ga pars plana vitrectomy (PPV) and 25-ga PPV combined with phacoemulsification surgery for managing ciliary block (malignant) glaucoma. The medical records of 11 eyes, in nine consecutive patients with malignant glaucoma were retrospectively reviewed to determine the efficacy of 25-ga PP...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9974-0
更新日期：2015-08-01 00:00:00
abstract：:Roussel and Fankhauser have proposed contact glasses with a collecting front surface centred on the bundle focus for use with high power lasers. We demonstrate here that the main contribution to the gain in energy density within the focus spot must be attributed to the front surface of the glass. This is at variance w...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00165111
更新日期：1984-06-01 00:00:00
abstract：:Blindness in diabetics is largely due to retinopathy and/or cataract. Hyperglycaemia and the duration of diabetes are major risk factors for the development of cataract and retinopathy. This review details some of the reactions of glucose that are relevant to the development of complications, and follows the elucidati...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00150976
更新日期：1991-01-01 00:00:00
abstract：PURPOSE:State Gentamicin antibiotic prophylaxis is contraindicated in 25 gauge Transconjunctival Sutureless Vitrectomy. METHODS:A 75-year-old diabetic woman was affected by glaucoma and mild diabetic retinopathy in both eyes, and epiretinal membrane in the left eye. A 25-gauge Transconjunctival Sutureless Vitrectomy (...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9148-4
更新日期：2008-10-01 00:00:00
abstract：:To study and classify epiretinal membranes (ERMs) based on spectral domain optical coherence tomography (SD-OCT) findings. One hundred and twelve patients with ERMs were examined clinically and underwent OCT examination. The anatomical structure of the macula and vitreoretinal interface was studied. ERMs were classifi...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9975-z
更新日期：2015-08-01 00:00:00
abstract：:We examined nine patients who presented cilioretinal artery occlusion (CLRAO) associated with retinal vein occlusion (RVO). CLRAO was probably secondary to the raised intraluminal resistance consequent to the RVO in patients showing initially a delayed filling of the cilioretinal artery in fluorescein angiography. Int...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF01007789
更新日期：1993-10-01 00:00:00
abstract：:To evaluate the efficacy of golimumab on severe and frequent recurrent anterior uveitis in patients with HLA-B27-positive ankylosing spondylitis. In this study, 15 eyes of 12 HLA-B27-positive AS patients with resistant anterior uveitis who received 50 mg of subcutaneous golimumab (Gol) per month due to frequent uveiti...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0239-y
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVES:To compare the intraocular pressure (IOP)-lowering effects of ripasudil, a rho-kinase inhibitor, and selective laser trabeculoplasty (SLT) as adjuvant therapy in Japanese glaucoma patients and to identify the factors associated with treatment success. METHODS:We performed a retrospective medical chart revie...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01615-x
更新日期：2020-10-20 00:00:00
abstract：PURPOSE:To compare the systemic and ocular characteristics and laboratory findings of patients developing toxic anterior segment syndrome (TASS) after uneventful phaco surgery with unaffected subjects undergoing the same surgery in the same session. DESIGN:A retrospective case-control study. METHODS:The study group c...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0418-x
更新日期：2018-02-01 00:00:00
abstract：:In a study of 95 patients with intraocular foreign body injuries presenting in the eight year period from 1978-1986 we found the overall visual results to be good with 62% of patients achieving a final visual acuity of 6/18 or better. The factors leading to a poor visual result were a large intraocular foreign body, p...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00137136
更新日期：1988-01-01 00:00:00
abstract：PURPOSE:The purpose of this article was to introduce a novel surgical technique for the management of peripheral Descemet's membrane perforation during deep anterior lamellar keratoplasty (DALK). METHODS:First, a thin stromal patch was prepared either from the anterior stromal lamella cut during DALK or from the anter...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-01065-6
更新日期：2019-10-01 00:00:00
abstract：:Fifty patients who developed preretinal or papillary neovascularization following tributary vein occlusion were treated by laser photocoagulation. Areas of non-perfused retina within the distribution of the obstructed vein were identified by fluorescein angiography and ablated using moderately intense laser photocoagu...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130697
更新日期：1981-05-01 00:00:00
abstract：:We report on two cases of bilateral chorioretinal colobomas with ocular anomalies in patients with CHARGE syndrome. In the first case, a female infant was born at 36 + 5 weeks gestation. At birth, the patient demonstrated a small left eye. Slit-lamp examination revealed colobomas of both irises. Fundus examination sho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9817-4
更新日期：2014-06-01 00:00:00
abstract：:The aim of this study is to determine the incidence of cystoid macular edema (CME) following repositioning and McCannel iris-suturing of dislocated intraocular lenses. This study is conducted in an urban private practice. A retrospective chart review was performed on consecutive patients who presented with posteriorly...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9964-2
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To report a case of toxic optic neuropathy caused by an ocular bee sting. METHODS:Case report and literature review. RESULTS:A 44-year-old female presented with no light perception vision 2 days after a corneal bee sting in her right eye. She was found to have diffuse cornea edema with overlying epithelial de...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0978-z
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:To investigate the efficacy of intravitreal injection of triamcinolone acetonide in the management of papillophlebitis and associated cystoid macular edema. METHODS:This study was a retrospective medical records review of four eyes of four patients (three males and one female) who had approximately 2-4 mont...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9128-8
更新日期：2008-08-01 00:00:00
abstract：:In 15 eyes with uncontrolled aphakic/pseudophakic glaucoma, trabeculectomy with anterior vitrectomy was performed. Mean pre-operative intraocular pressure (IOP) was 38.2 +/- 6.7 mmHg and mean post operative IOP was 19.3 +/- 5.2 mmHg after follow-up of 11.2 2 months. The anterior chamber maintainer technique during vit...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00153920
更新日期：1991-05-01 00:00:00
abstract：:Transvitreal pars plana sclerotomy using the contact Nd:YAG laser with a sapphire probe was performed on a group of rabbit eyes and compared with a similar procedure performed with a Ziegler knife. Although the intraocular pressure (IOP) was lowered in both groups of animals, the reduction was greater and more lasting...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130620
更新日期：1988-01-01 00:00:00
abstract：:We report our experience with three cases of Epstein-Barr virus (EBV)-associated uveitis. These patients had the following common clinical features: 1) a common cold-like prodrome, 2) bilateral involvement, 3) severe acute anterior uveitis with fibrinous exudate, 4) granulomatous anterior uveitis in the chronic stage,...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00163559
更新日期：1990-10-01 00:00:00
