Abstract:
:Blindness in diabetics is largely due to retinopathy and/or cataract. Hyperglycaemia and the duration of diabetes are major risk factors for the development of cataract and retinopathy. This review details some of the reactions of glucose that are relevant to the development of complications, and follows the elucidation of monosaccharide autoxidation and its relevance to the aldose reductase reaction and its determination. Inhibitors of this 'aldose reductase' reaction are shown to have a number of effects which may be of importance to their action in vivo. The pharmacological implications of chemotherapy for diabetics with complications are briefly discussed.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Crabbe MJdoi
10.1007/BF00150976subject
Has Abstractpub_date
1991-01-01 00:00:00pages
25-36issue
1eissn
0165-5701issn
1573-2630journal_volume
15pub_type
杂志文章,评审abstract:UNLABELLED:We examined the immunocytochemical features of after cataract tissue and cataractous lens epithelium prior to cataract surgery and at the time of surgery. METHODS:This study included 23 cases. Antibodies against the following antigens were used: epidermal growth factor (EGF), EGF receptor (EGF-R), fibroblas...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1010640118852
更新日期:1999-01-01 00:00:00
abstract::The Hermansky-Pudlak Syndrome, a "tyrosinase positive' form of oculocutaneous albinism, is a triad comprising albinism, a hemorrhagic diathesis and ceroid-lipofuscin storage. A pedigree is presented showing consanguinity with a pattern of pseudodominance. Electroretinography in two isolated Hermansky-Pudlak subjects w...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00139585
更新日期:1981-08-01 00:00:00
abstract::Myelinated retinal nerve fibers (MRNF) represent an asymptomatic developmental anomaly in which myelin sheaths extend to a group of retinal nerve fibers along their intraocular portion. The additional volume of the myelin sheaths causes displacement of the axons toward the vitreous body. We investigated the effect of ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0207-6
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:To assess ophthalmic manifestations in patients with stroke and emphasize the importance of a formal screening for visual problems in stroke patients in hospital and rehabilitation settings. METHODS:This was a cross-sectional study of 50 newly diagnosed patients with stroke with Glasgow Coma Scale (GCS) > 8 ex...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01131-7
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To present the long-term results of therapeutic keratoplasty for microbial keratitis in moderate to advanced phases. METHODS:The medical records of 44 patients who underwent therapeutic keratoplasty for microbial keratitis at the ophthalmology clinic of a training and research hospital between June 2012 and Ma...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01538-7
更新日期:2020-12-01 00:00:00
abstract::The melanocytoma of the optic disc is a deeply-pigmented tumor located on the optic nerve head. In contrast to malignant melanoma, it appears to occur in equal frequency in whites and non-whites. Histologically, it consists of deeply-pigmented plump nervus cells with benign characteristics. No treatment is usually nec...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00133275
更新日期:1978-09-01 00:00:00
abstract::The objective of this study is to evaluate the visual prognosis and postoperative course in advanced glaucoma patients who underwent trabeculectomy. The records of 30 patients with advanced visual field (VF) defects undergoing trabeculectomy were retrospectively reviewed. Severe VF defects were defined as those with a...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-011-9494-0
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To present recurrent corneal erosion (RCE) caused by late suture exposure after blepharoplasty. METHODS:Four patients who have unilateral RCE were found to have previous blepharoplasty. The RCE was associated with late suture exposure. The clinical courses, characteristics, methods to identify the suture expos...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0936-9
更新日期:2019-06-01 00:00:00
abstract::Pigmented rabbits were treated with timolol maleate, betaxolol hydrochloride or levobunolol hydrochloride eye drops twice a day for six months. Animals of the same age group and breed were used as controls. There were no differences observed in corneal epithelium with light and transmission electron microscopy. With s...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF02028643
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION AND AIM:To compare intraocular pressure (IOP) measurements obtained with non-contact tonometry (NCT), Icare rebound tonometry (IRT) and Goldmann applanation tonometry (GAT) in pediatric cases and to examine the effect of topical anesthesia on measurements obtained using IRT. MATERIALS AND METHODS:Pediatri...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01375-8
更新日期:2020-08-01 00:00:00
abstract::The purpose is to report a case of Candida interface infection after deep anterior lamellar keratoplasty (DALK). A 23-year-old female patient underwent DALK surgery in the left eye for keratoconus. Four weeks after the surgery, she presented with asymptomatic white-cream colored deposits at the graft-host interface. E...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9545-1
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:To compare capillaries perfusion in macular areas at different layers and peripapillary region in radial peripapillary capillaries (RPC) between healthy subjects and subjects with obstructive sleep apnea-hypopnea (OSA) using spectral-domain optical coherence tomography angiography (OCTA). METHODS:Totally 16 ey...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01518-x
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To evaluate the influence of strong fixation preference on clinical and surgical outcomes, in non-amblyopic patients with basic-type intermittent exotropia (IXT). MATERIALS AND METHODS:The records of patients were retrospectively investigated. Non-amblyopic patients with the diagnosis of basic-type IXT were en...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01603-1
更新日期:2020-10-14 00:00:00
abstract::We report an unusual case of disseminated cysticercosis having simultaneous intraocular and extraocular involvement. This 21-year-old male presented with recent loss of vision in one eye and history of a single seizure. Examination revealed intravitreal cysticercosis with exudative retinal detachment. Computed tomogra...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-005-8248-2
更新日期:2005-02-01 00:00:00
abstract::Several different sets of criteria have been proposed to establish the diagnosis of Vogt-Koyanagi-Harada disease (VKH). Various investigators have used the criteria proposed by Sugiura, those proposed by by the American Uveitis Society as well as the revised diagnostic criteria proposed by the First VKH International ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-006-9021-x
更新日期:2007-04-01 00:00:00
abstract::Bietti crystalline corneoretinal dystrophy (BCD, MIM 210370) is a type of hereditary retinal disorder which commonly occurs in China. It is known that mutations in the CYP4V2 gene result in BCD. The purpose of this study was to investigate the case of a Chinese family and characterize the polymorphisms of the CYP4V2 g...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9686-2
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy. METHODS:Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations ...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1007/s10792-017-0685-1
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To compare stage of visual field loss (VFL) and age at diagnosis between patients with different types of glaucoma with regard to glaucoma screening and driving ability. METHODS:In a cross-sectional study of 1988 consecutive patients with different types of glaucoma VFL at diagnosis and age at diagnosis were a...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0477-7
更新日期:2018-04-01 00:00:00
abstract::This paper builds on results of a previous paper on the prevalence of trachomatous visual impairment as the foundation for assessing the global burden of trachomatous blindness and low vision: approximately 2.9 million cases of trachomatous blindness and 3.8 million low visioned corresponding to a global prevalence of...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00130921
更新日期:1995-01-01 00:00:00
abstract::To evaluate the potential benefit of intraocular pressure (IOP) reduction in normal-tension glaucoma (NTG) patients in South Korea. A retrospective, multi-center analysis of Korean NTG patients with 5-years follow-up, typical glaucomatous optic disc and/or visual field changes and no recorded IOP >21 mmHg. Progression...
journal_title:International ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10792-011-9463-7
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:To provide normal corneal elevation data for a large Caucasian population and to determine the impacts on these data of age, sex, axial length (AXL) and horizontal white-to-white (WW). SETTING:Centro Internacional de Oftalmología Avanzada, Madrid, Spain. DESIGN:Retrospective, cross-sectional, observational. ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-1028-6
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:To describe and analyze short-term posterior vitreous abnormalities following intravitreal ocriplasmin in eyes with symptomatic vitreomacular traction syndrome (VMT). METHODS:In this institutional, prospective and interventional study enrolled patients with symptomatic focal VMT syndrome treated with intravitr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01177-7
更新日期:2020-01-01 00:00:00
abstract::Preliminary results of a larger investigation on correlation between Retinal Nerve Fiber Layer Defects (RNFL) and Automated Perimetry (AP) are presented. A group of ocular hypertensive patients was recruited and a cross-section, randomized study was carried out. The group was composed of 54 eyes from 28 patients; 15 m...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00917968
更新日期:1992-09-01 00:00:00
abstract::The choroidal vascular bed has many interesting features such as relatively wide but flat capillaries, fenestrated capillary walls and an enormous blood flow. The high flow rate results in a high oxygen tension in the tissue and is also of importance in the temperature control of the eye. The capillary wall is permeab...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00127638
更新日期:1983-02-01 00:00:00
abstract:BACKGROUND:Autoenucleation is a severe, rare form of self-mutilation. The majority of cases have been reported in the 15- to 60-year age group, usually in psychiatric patients with a history of depression or schizophrenia, sometimes caused by drug abuse. CASE REPORT:We report a case of left-sided autoenucleation in an...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9222-6
更新日期:2009-08-01 00:00:00
abstract::I have developed two protective caps that fit on the viewing windows of the indirect ophthalmoscope. These caps contain filters that absorb the argon laser beam and protect the operator's eyes during endolaser treatment. ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00225937
更新日期:1986-04-01 00:00:00
abstract::To evaluate the effect of intravitreal bevacizumab (IVB) before Ahmed valve implantation for treatment of neovascular glaucoma (NVG). This study is a retrospective, comparative, consecutive case series. The study group consisted of 27 eyes of 26 patients with NVG who underwent an Ahmed valve implantation. Thirteen eye...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9875-7
更新日期:2014-08-01 00:00:00
abstract::To evaluate the effect of intracameral carbachol on foveal thickness in patients who underwent uneventful cataract surgery. This retrospective study included two groups: the study group patients (group 1, n = 47 eyes) had uneventful cataract surgery and received only carbachol 0.01 % for miosis; the control group pati...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9579-4
更新日期:2012-10-01 00:00:00
abstract::The purpose of this study was to determine the causes of childhood visual impairment and blindness in students of a school for blind children, to determine how many students had some residual vision, and to evaluate any unmet low-vision care. A survey of students in the blind school was conducted in two parts in May-J...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9134-x
更新日期:2008-10-01 00:00:00
abstract::We report the functional outcome of a patient who had undergone Boston keratoprosthesis type I for extensive ocular surface damage caused by latex of Euphorbia. The milky sap or latex of the Euphorbia plant is highly toxic and an irritant to the skin and eye. Damage to the eye ranges from mild to severe corneal edema,...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9515-7
更新日期:2012-02-01 00:00:00