Abstract：
:To evaluate the potential benefit of intraocular pressure (IOP) reduction in normal-tension glaucoma (NTG) patients in South Korea. A retrospective, multi-center analysis of Korean NTG patients with 5-years follow-up, typical glaucomatous optic disc and/or visual field changes and no recorded IOP >21 mmHg. Progression was identified by Advanced Glaucoma Intervention Study visual field scoring. There were 90 (42%) progressed patients and 127 (58%) stable patients included in the study. Mean IOP measured higher in the progressed (14.3 ± 2.2 mmHg) than stable patients (14.0 ± 1.9 mmHg), but was not statistically different between the groups (P = 0.29). The mean IOP that best discriminated stable patients was ≤15 mmHg, but no statistical difference existed in the numbers of progressed versus stable patients at ≤15 mmHg compared to >15 mmHg (P = 0.07). Multivariate regression analysis showed that the baseline number of glaucoma medicines and visual field as well as mean, peak and fluctuation of IOP were significant risk factors for glaucomatous progression (P < 0.01). This study suggests that in Korean NTG patients, despite relatively similar IOPs between progressed and stable patients, and based on multivariate regression analysis, IOP may be a risk factor for glaucomatous progression.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Ma KT,Kim CY,Seong GJ,Lee SH,Park JW,Ha SJ,Cho BJ,Stewart JA,Kristoffersen MS,Nelson LA,Stewart WCdoi
10.1007/s10792-011-9463-7subject
Has Abstractpub_date
2011-10-01 00:00:00pages
355-61issue
5eissn
0165-5701issn
1573-2630journal_volume
31pub_type
杂志文章,多中心研究abstract：:We report on two cases of bilateral chorioretinal colobomas with ocular anomalies in patients with CHARGE syndrome. In the first case, a female infant was born at 36 + 5 weeks gestation. At birth, the patient demonstrated a small left eye. Slit-lamp examination revealed colobomas of both irises. Fundus examination sho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9817-4
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:Traditional color vision tests depend on subjective judgments and are not suitable for infant children and subjects with cognitive dysfunction. We aimed to explore an objective and quantitative color vision testing method based on sweep steady-state visual evoked potentials (sweep SSVEPs) and compare the result...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01613-z
更新日期：2020-10-12 00:00:00
abstract：PURPOSE:The aim of this study was to evaluate the corneal biomechanical parameters in patients with ankylosing spondylitis (AS) and to compare them with the healthy subjects. METHODS:Sixty patients with AS (study group) and 60 healthy subjects (control group) were enrolled in this prospective study. The study group wa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0368-3
更新日期：2017-08-01 00:00:00
abstract：:Ewing's sarcoma is a small, blue, round-cell tumor of mesenchymal origin which typically presents itself during the first and the second decades of life. Typically, it is noticed in the long bones of the limbs, pelvis, or ribs. There have been few reports worldwide with none in Pakistan of this rare phenomenon. We rep...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9937-5
更新日期：2014-10-01 00:00:00
abstract：:A national study was conducted in children attending six schools for the blind in Malaysia to identify the anatomical site and underlying causes of blindness (BL) and severe visual impairment (SVI), with a view to determine the potentially preventable and treatable causes so that appropriate control measures can be im...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014493228691
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:Proliferative vitreoretinopathy (PVR) is characterized by the formation of cellular membranes on the detached retina and also in the vitreous. Glial cells can be found in epiretinal and subretinal membranes from eyes with PVR, proliferative diabetic retinopathy (PDR), idiopathic macular pucker, uveitis and othe...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1022509614815
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To examine the retinal layers' changes and alterations in retinal microvasculature in patients with rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy (PPV). METHODS:Participants in this study were 103 patients with RRD, 85 macula off and 18 macula on, who were treated with PPV and gas ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01521-2
更新日期：2020-12-01 00:00:00
abstract：:Aqueous flare and cells are the two inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barriers. When examined with the slit lamp, measurement of intraocular inflammation remains subjective with considerable intra- and interobserver variations. Laser flare cell photo...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-009-9310-2
更新日期：2010-10-01 00:00:00
abstract：:The clinical and histopathological findings are described in a case of cerebral and ocular abnormalities associated with (congenital) muscular dystrophy. Histopathological examination of the eyes revealed a fetal configuration of the anterior chamber angle, elongated ciliary processes, cataract, persistence of primary...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF01007744
更新日期：1993-08-01 00:00:00
abstract：PURPOSE:To evaluate the effects of epiretinal membrane (ERM) formation on the anatomic and functional results of subjects with diabetic macular edema (DME) who are receiving intravitreal aflibercept injections (IAIs). MATERIALS AND METHODS:This retrospective comparative study includes 29 eyes with DME (Group 1) and 43...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01444-y
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:To investigate the dry eye symptoms after cataract surgery in MGD patients and their relationships METHODS: The study included 115 patients (115 eyes) with age-related cataract that underwent uncomplicated cataract surgery, and the patients were divided into two groups according to the MGD diagnostic criteria...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01294-8
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:To evaluate the additional intraocular pressure (IOP) lowering effect of gonioscopy-assisted transluminal trabeculotomy (GATT) to contemporary goniosynechialysis (GSL) in endeavouring to abolish subsequent occlusion after chronic iridotrabecular contact in primary angle closure (PAC) patients. METHODS:A retros...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01676-y
更新日期：2021-01-03 00:00:00
abstract：INTRODUCTION:The aim of this prospective study is to verify, in terms of both early postoperative complications and intraocular pressure (IOP) outcomes, the performance of a scleral flap removable suture. MATERIALS AND METHODS:Sixty-six patients that underwent trabeculectomy were randomly divided into two groups: in t...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-008-9245-z
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:A case report of recurrent unilateral granulomatous iridocyclitis with ocular hypertension without retinitis caused by cytomegalovirus (CMV) in an immunocompetent patient. METHODS:Aqueous humor was analysed by multiplex PCR to detect viral DNA, and real-time PCR was used to evaluate virus copies before and ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9090-5
更新日期：2007-12-01 00:00:00
abstract：:Spontaneous hyphema has been linked to many conditions. We describe a patient with recurrent spontaneous hyphema caused by an abnormal angle vessel without associated rubeosis iridis, glaucoma, or other vascular abnormalities as documented by iris fluorescein angiography. After treatment with several sessions of argon...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136495
更新日期：1985-09-01 00:00:00
abstract：PURPOSE:To compare capillaries perfusion in macular areas at different layers and peripapillary region in radial peripapillary capillaries (RPC) between healthy subjects and subjects with obstructive sleep apnea-hypopnea (OSA) using spectral-domain optical coherence tomography angiography (OCTA). METHODS:Totally 16 ey...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01518-x
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To evaluate whether retrobulbar blood flow and choroidal thickness (CT) are affected in patients with rheumatoid arthritis (RA), and the relationship between these values. METHODS:We evaluated 40 eyes of 20 RA patients and 40 eyes of 20 healthy controls. The enhanced depth imaging optical coherence tomography,...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0656-6
更新日期：2018-10-01 00:00:00
abstract：:Ocular wall dimensions (axial eye length, anterior chamber depth, lens thickness, vitreous length, thickness and volume of the ocular wall) were determined by echobiometry on 10 eyes of 10 patients with glaucoma one day before and four days after trabeculectomy. The results showed significant differences: decreased ax...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00917990
更新日期：1992-09-01 00:00:00
abstract：PURPOSE:Corneal melting with perforation is a severe ophthalmic complication of autoimmune disorders such as rheumatoid arthritis. It requires urgent medical management in order to maintain the integrity of the globe and preserve vision. Treating this complication by penetrating keratoplasty is problematic due to the h...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0545-z
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To assess safety and efficacy of deep topical anesthesia with ropivacaine-soaked sponge compared with topical anesthesia with oxybuprocaine in patients undergoing phacoemulsification. METHODS:This was a retrospective study where records of patients operated for cataract were evaluated. Patients using a visual ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01132-6
更新日期：2019-12-01 00:00:00
abstract：:To evaluate the efficacy of 25-ga pars plana vitrectomy (PPV) and 25-ga PPV combined with phacoemulsification surgery for managing ciliary block (malignant) glaucoma. The medical records of 11 eyes, in nine consecutive patients with malignant glaucoma were retrospectively reviewed to determine the efficacy of 25-ga PP...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9974-0
更新日期：2015-08-01 00:00:00
abstract：:The purpose of this study was to report various conditions masquerading as congenital nasolacrimal duct obstruction (CNLDO). Retrospective review was designed in a tertiary hospital setting. 92 eyes of 65 consecutive patients were included in this study. All patients presenting with CNLDO symptomatology but where the ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0050-1
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Autoenucleation is a severe, rare form of self-mutilation. The majority of cases have been reported in the 15- to 60-year age group, usually in psychiatric patients with a history of depression or schizophrenia, sometimes caused by drug abuse. CASE REPORT:We report a case of left-sided autoenucleation in an...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9222-6
更新日期：2009-08-01 00:00:00
abstract：PURPOSE:The aim of the study reported here was to assess the influence of serum HbA1c levels on foveal choroidal thickness in diabetic patients. METHODS:A total of 122 eyes from 122 patients who had type 2 DM were studied in this prospective, cross-sectional study. Patients were divided into three groups: 43 patients ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0668-2
更新日期：2018-10-01 00:00:00
abstract：:Gyrate atrophy of the choroid and retina is caused by deficient activity of ornithine ketoacid aminotransferase, a pyridoxal phosphate dependent enzyme. Besides the typical eye findings, abnormalities have been found on muscle biopsy, electro-encephalography, electromyography and electrocardiography, establishing this...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00139577
更新日期：1981-08-01 00:00:00
abstract：PURPOSE:This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy. METHODS:Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations ...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-017-0685-1
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:To investigate the risk factors associated with corneal epithelial defects (CED) and delayed healing (exceeding 1 week) following pars plana vitrectomy (PPV). METHODS:This retrospective study enrolled patients who underwent PPV at a single center in Taiwan between 2011 and 2012. Medical records were reviewed, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0429-7
更新日期：2018-02-01 00:00:00
abstract：:Carotid cavernous fistulas (CCFs) can be classified as direct and indirect, depending on their flow rates and their etiology. Both forms can cause the same characteristic ophthalmological symptoms and signs. We analyzed these ocular characteristics and determined the prognostics factors associated with treatment outco...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9550-4
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:To evaluate the long-term safety and efficacy of Mycophenolate Mofetil (MMF) for the control of cystoid macular oedema (CMO) secondary to noninfectious uveitis (NU). METHODS:The medical records of 19 consecutive patients with inflammatory CMO treated with MMF were retrospectively reviewed. Patient demographics...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9200-z
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PE...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0498-2
更新日期：2018-04-01 00:00:00
