Abstract：
:A national study was conducted in children attending six schools for the blind in Malaysia to identify the anatomical site and underlying causes of blindness (BL) and severe visual impairment (SVI), with a view to determine the potentially preventable and treatable causes so that appropriate control measures can be implemented in the future. The standardized clinical examination of eyes was performed and the findings were recorded on the WHO Prevention of Blindness Programme eye examination record form for children with blindness and low vision. A total of 358 children aged between 7 and 17 years were examined, of whom 332 (92.7%) were blind or severely visually impaired. The results relate to these 332 children. Lens was the major anatomical site (22.3%) of visual loss followed by retina (20.8%), whole globe (17.2%), cornea (15.1%), optic nerve (8.7%) and uvea (5.1%). Glaucoma was responsible for BL/SVI in 7.2% and others in 3.6% of cases. Hereditary diseases were responsible for visual loss in 29.5%, intrauterine factors in 4.5%, perinatal factors in 9% and childhood factors in 7.8% of cases. However, the aetiology was unknown in 49.1% of cases which included congenital anomalies of the globe. Childhood cataract and corneal scarring are major treatable causes of BL/SVI that can benefit from future intervention strategies. Perinatal screening for intrauterine factors and hereditary eye diseases, and appropriate interventional therapy will help in reducing the prevalence of childhood blindness.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Reddy SC,Tan BCdoi
10.1023/a:1014493228691subject
Has Abstractpub_date
2001-01-01 00:00:00pages
53-9issue
1eissn
0165-5701issn
1573-2630journal_volume
24pub_type
杂志文章abstract：PURPOSE:The aim of this pilot study was to evaluate a new semiautomatic procedure to assess in vivo changes in the crystalline lens and ciliary muscle during accommodation. METHODS:A total of 14 subjects were divided into two groups, young (aged between 20 and 25 years) and adult (aged between 35 and 40 years), and me...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0752-7
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Optic disc drusen (ODD) are acellular deposits in the prelaminar optic nerve head. The most accredited theory is that they are secondary to abnormalities in axonal metabolism and degeneration, but the pathogenesis is not clear to date. CLINICAL MANIFESTATION:Although ODD are often considered a benign condit...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-020-01365-w
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of long-tube shunt surgery (LTSS) without valve in uveitic glaucoma (UG) eyes. METHODS:We retrospectively analyzed the data of 45 UG eyes that underwent only LTSS or LTSS combined with trabeculectomy (TLE) (LTSS/TLE). The UG eyes were analyzed by categorizing them into granulomatous/no...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01601-3
更新日期：2020-10-14 00:00:00
abstract：:Diplopia is a very disturbing condition that has been reported as a complication of several surgical procedures. The following review aims to identify the ocular and nonocular surgical techniques more often associated with this undesirable result. Diplopia is reported as an adverse outcome of some neurosurgical proced...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9927-7
更新日期：2014-08-01 00:00:00
abstract：:Insulin-like growth factor-1 (IGF-1) is altered in several neurodegenerative diseases, the association between serum IGF-1 levels and glaucoma has not been evaluated. This study was designed to evaluate whether serum IGF-1 levels are different in patients with Pseudoexfoliation (PEX) with or without glaucoma. The stud...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0271-y
更新日期：2017-04-01 00:00:00
abstract：:Corneal ulcer is a devastating corneal disease which is potentially sight-threatening and conventionally is treated by topical antibiotics and in some cases with more invasive procedures such as keratoplasty. The aim of this study is to evaluate the efficacy of corneal collagen cross-linking in resistant corneal ulcer...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-012-9633-2
更新日期：2013-02-01 00:00:00
abstract：:To assess the effect of intravitreal dexamethasone implant (Ozurdex) for the treatment of macular edema secondary to retinal vein occlusion (RVO) resistant to repeated intravitreal ranibizumab injection. Retrospective review of 11 patients (11 eyes) with ranibizumab-resistant macular edema secondary to RVO. Macular ed...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0226-3
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:The authors investigated the use of dapiprazole, an alpha-adrenergic blocking agent, in preventing pigment release and IOP increase after exercise in patients affected with PDS. METHODS:Three young myopic males (31, 34 and 35 years old) affected with pigmentary dispersion syndrome performed 30 minutes of joggi...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130855
更新日期：1995-01-01 00:00:00
abstract：:Gyrate atrophy of the choroid and retina is caused by deficient activity of ornithine ketoacid aminotransferase, a pyridoxal phosphate dependent enzyme. Besides the typical eye findings, abnormalities have been found on muscle biopsy, electro-encephalography, electromyography and electrocardiography, establishing this...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00139577
更新日期：1981-08-01 00:00:00
abstract：PURPOSE:To examine the retinal layers' changes and alterations in retinal microvasculature in patients with rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy (PPV). METHODS:Participants in this study were 103 patients with RRD, 85 macula off and 18 macula on, who were treated with PPV and gas ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01521-2
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To investigate the effects of glaucomatous damage on the mfVEP parameters of patients suffering from primary open-angle glaucoma (POAG). METHODS:Fifteen healthy subjects and 15 patients with unilateral POAG participated in this study. In addition, routine ophthalmological examinations including visual acuity, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01138-0
更新日期：2019-12-01 00:00:00
abstract：:We present an unusual case of polypoidal choroidal vasculopathy (PCV) lying above the retinal pigment epithelium (RPE) in a 60-year-old Caucasian female. PCV lesions are typically located beneath the RPE layer. However, they may rarely lie above the level of the RPE due to a discontinuity in the RPE and Bruch's membra...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9681-7
更新日期：2013-02-01 00:00:00
abstract：AIM:To evaluate the whether intravitreal erythropoietin (EPO) administration has any beneficial or adverse effect in patients with late-stage optic neuropathy (ON) or not. METHODS:The study examined 16 eyes of 16 patients who had late-stage ON and ≥1/20 best-corrected visual acuity (BCVA) in their affected eye. There ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0553-z
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To compare the outcome of penetrating keratoplasty (PKP) and deep anterior lamellar keratoplasty (DALK) in the surgical management of keratoconus (KC). PATIENT AND METHODS:A retrospective review was conducted of the medical records of all patients treated with PKP or DALK for KC at University of Iowa Hospitals...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9393-9
更新日期：2010-12-01 00:00:00
abstract：:The aim of this study is to determine the incidence of cystoid macular edema (CME) following repositioning and McCannel iris-suturing of dislocated intraocular lenses. This study is conducted in an urban private practice. A retrospective chart review was performed on consecutive patients who presented with posteriorly...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9964-2
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:The aim of the study reported here was to assess the influence of serum HbA1c levels on foveal choroidal thickness in diabetic patients. METHODS:A total of 122 eyes from 122 patients who had type 2 DM were studied in this prospective, cross-sectional study. Patients were divided into three groups: 43 patients ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0668-2
更新日期：2018-10-01 00:00:00
abstract：:To compare the efficacy of 5-fluorouracil (5-FU) with mitomycin C (MMC) in preventing pterygium recurrence when used as an adjuvant following pterygium excision with conjunctival autograft. Low-dose MMC combined with conjunctival autograft is an effective treatment for preventing recurrence following pterygium excisio...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-011-9509-x
更新日期：2012-02-01 00:00:00
abstract：PURPOSE:Primary ocular adnexal lymphomas are cured by radiotherapy; however, complications are frequent and relapses may occur. In this case, we aimed to report the efficacy and safety of extended systemic rituximab (anti-CD 20 monoclonal antibody) therapy of conjunctival mucosa-associated lymphoid tissue (MALT) lympho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0844-z
更新日期：2019-03-01 00:00:00
abstract：:In order to evaluate possible etiological factors and the natural course of 'idiopathic' preretinal fibrosis in young persons, nine consecutive patients with macular pucker diagnosed under the age of 50 years were examined. There were six women and three men with the mean age of 27.2 years (range 15-50) and the mean f...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00202776
更新日期：1987-02-01 00:00:00
abstract：:The purpose of this study was to report on two novel missense mutations of the cornea-specific TGFBI gene in one single patient and in two generations of a family diagnosed with unique corneal dystrophy (CD) phenotypes. Ophthalmologic examination, in several cases ocular coherence tomography of the anterior segment (A...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0216-5
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:To report a case of DUSN from the Indian subcontinent and emphasize the importance of immediate photocoagulation. METHOD:Review of case record. RESULT:The referring ophthalmologist had photographed the subretinal worm but had not undertaken laser photocoagulation. On presentation to us the patient had feature...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9045-x
更新日期：2005-12-01 00:00:00
abstract：:To describe a congenital retinal macrovessel with macular thickening. This case was investigated using fundus photography, fluorescein angiography, Spectralis optical coherence tomography and a 10-2 visual field test. A 23-year-old man was referred to our clinic with decreased vision in the right eye. Fundus examinati...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9402-z
更新日期：2011-02-01 00:00:00
abstract：INTRODUCTION:We report on a 62-year-old healthy woman who suffered from bilateral predescemetic opacities, where the underlying disorder could not be identified. She had bilateral keratopathy with corneal edema, a diffuse predescemetic avascular haze and deszemetic folds. Because of high hyperopia (right +7.50/left +7....
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/b:inte.0000018521.88103.17
更新日期：2004-01-01 00:00:00
abstract：:A 17-year-old female presented to our hospital with fatigue, arthralgia and fever associated with non-granulomatous anterior uveitis in the left eye. Blood tests revealed renal failure and a renal biopsy showed acute tubulointerstitial nephritis. Findings were consistent with tubulointerstitial nephritis and uveitis (...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9820-9
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:We aimed to analyze the clinical characteristics of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome. Furthermore, we aimed to correlate the number and location of retinal aneurysms with the size of retinal non-perfusion area and neovascularization. METHODS:Six patients with IRVAN ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0962-7
更新日期：2019-07-01 00:00:00
abstract：UNLABELLED:We examined the immunocytochemical features of after cataract tissue and cataractous lens epithelium prior to cataract surgery and at the time of surgery. METHODS:This study included 23 cases. Antibodies against the following antigens were used: epidermal growth factor (EGF), EGF receptor (EGF-R), fibroblas...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1010640118852
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:To develop a new regression formula based on the Gaussian thick lens formula and to verify the accuracy of the regression formula. METHODS:In this prospective study, 207 eyes of 207 myopic subjects and 133 eyes of 67 postoperative subjects were included. For the 133 postoperative eyes, 127 eyes underwent laser...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01089-6
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:To evaluate one-year visual, refractive, and topographic outcomes of 58 eyes of 53 keratoconus patients who underwent surgery with a progressive thickness intrastromal corneal ring segment (ICRS). METHODS:This multi-center, retrospective, observational study evaluates the one-year effects of progressive thickn...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01467-5
更新日期：2020-11-01 00:00:00
abstract：:After glaucoma filtering surgery subconjunctival injection of human recombinant tissue plasminogen activator may promote the function of glaucoma filter bleb and increase outflow facility. It can also increase postoperative complications, such as corneal damage. The aim of our research was to determine corneal endothe...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00156413
更新日期：1995-01-01 00:00:00
abstract：:A 32-year-old lady presented with bilateral painful proptosis and left infranuclear facial palsy. She was mildly anemic. Ocular examination revealed a firm non-tender mass in the super lateral quadrant of both orbits. Fine-needle aspiration cytology from the orbital mass showed the presence of lymphoplasmacytoid cells...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9037-x
更新日期：2005-12-01 00:00:00
