Abstract：
AIM:To evaluate the whether intravitreal erythropoietin (EPO) administration has any beneficial or adverse effect in patients with late-stage optic neuropathy (ON) or not. METHODS:The study examined 16 eyes of 16 patients who had late-stage ON and ≥1/20 best-corrected visual acuity (BCVA) in their affected eye. There were nonarteritic ischemic ON in 10 (62.5%) eyes, traumatic ON in 4 (25.0%) eyes and methanol-induced ON in 2 (12.5%) eyes. Using pars plana approach, 2000 IU/0.2 ml EPO was administered intravitreally with a 30-gauge needle. Injections were administered three times with 6-week intervals. We compared the differences in the BCVA, intraocular pressure (IOP), retinal nerve fiber layer (RNFL) thickness, pattern visual evoked potentials (p-VEP) and pattern electroretinography (p-ERG) parameters performed at initial examination and final visits. RESULTS:The mean age of the patients was 52.38 ± 12.00 years; 2 (12.50%) of them were female, and 14 (87.50%) of them were male. The mean BCVA levels of 16 patients with optic atrophy were 1.12 ± 0.25 logMAR at the initial examination and 1.08 ± 0.26 logMAR at the final visit (p = 0.102). There was no statistically significant difference between the initial and final RNFL thicknesses, IOP values, p-ERG or p-VEP responses. CONCLUSIONS:Intravitreal EPO injections have no beneficial or detrimental effect on the late stage of ON. Further studies are necessary to compare our results in patients with ON in earlier stages.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Acar U,Kucuk B,Sevinc MK,Aykas S,Erdurmus M,Sobaci Gdoi
10.1007/s10792-017-0553-zsubject
Has Abstractpub_date
2018-06-01 00:00:00pages
1021-1025issue
3eissn
0165-5701issn
1573-2630pii
10.1007/s10792-017-0553-zjournal_volume
38pub_type
杂志文章abstract：:We describe a case illustrating a new technique of using intraoperative optical coherence tomography (IOCT) for foreign body removal from the limbus and cornea. In this case, fragments of a fish hook in the temporal limbus and cornea were identified on the OCT. The residual pieces were then removed, assisted by high-r...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0304-6
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVES:To determine the common eye diseases as well as the prevalence and causes of blindness and visual impairment in young adult residents of rural areas of Anambra State, Nigeria. MATERIALS AND METHODS:Three rural villages in Anambra State, Nigeria were selected by simple random sampling. A structured questionn...
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pub_type： 杂志文章
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更新日期：1998-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2012-08-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0202-y
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:Ripasudil accelerates aqueous humour drainage along the trabecular meshwork-Schlemm's canal route and has been approved for clinical use in Japan. We retrospectively investigated the efficacy and safety of adding ripasudil to existing treatment regimens to reduce intraocular pressure (IOP) in patients with glau...
journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：2018-02-01 00:00:00
abstract：PURPOSE:To report a case of resolution of retinal arterial aneurysms in a patient of idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) treated with oral steroids. METHODS:This study contains case report and review of literature. RESULTS:A 16-year-old girl with stage 2 IRVAN was treated with oral ste...
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pub_type： 杂志文章,评审
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更新日期：1987-10-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9973-1
更新日期：2015-08-01 00:00:00
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更新日期：2014-02-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9840-5
更新日期：2014-06-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00133274
更新日期：1978-09-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：2001-01-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9931-y
更新日期：2015-04-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0226-3
更新日期：2017-02-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s10792-020-01421-5
更新日期：2020-09-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00137371
更新日期：1983-01-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9515-7
更新日期：2012-02-01 00:00:00
abstract：PURPOSE:To report a case of toxic optic neuropathy caused by an ocular bee sting. METHODS:Case report and literature review. RESULTS:A 44-year-old female presented with no light perception vision 2 days after a corneal bee sting in her right eye. She was found to have diffuse cornea edema with overlying epithelial de...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0978-z
更新日期：2019-07-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00137136
更新日期：1988-01-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0623-2
更新日期：2018-08-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9148-4
更新日期：2008-10-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01518-x
更新日期：2020-12-01 00:00:00
abstract：INTRODUCTION AND AIM:To compare intraocular pressure (IOP) measurements obtained with non-contact tonometry (NCT), Icare rebound tonometry (IRT) and Goldmann applanation tonometry (GAT) in pediatric cases and to examine the effect of topical anesthesia on measurements obtained using IRT. MATERIALS AND METHODS:Pediatri...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01375-8
更新日期：2020-08-01 00:00:00
abstract：:The main visual field indices of Flammer and the analogous ones of Heijl have been compared based on a population of 113 glaucomatous visual fields. It is shown that for the population studied, the differences between the two sets of indices are negligible for Octopus G1 program results and that they may thus be used ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00128955
更新日期：1991-09-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9938-4
更新日期：2015-04-01 00:00:00
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journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1023/a:1026490902566
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:To investigate the effects of glaucomatous damage on the mfVEP parameters of patients suffering from primary open-angle glaucoma (POAG). METHODS:Fifteen healthy subjects and 15 patients with unilateral POAG participated in this study. In addition, routine ophthalmological examinations including visual acuity, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01138-0
更新日期：2019-12-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01345-0
更新日期：2020-07-01 00:00:00
abstract：:Diabetes mellitus and pregnancy have reciprocal influences between them, therefore diabetes mellitus may complicate the course of pregnancy as well as pregnancy can worsen the performance of diabetes especially at the fundus oculi. Several factors seem to play a role in retinal neovascularization. Actually it's not po...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9906-z
更新日期：2014-08-01 00:00:00
