Abstract:
INTRODUCTION:The aim of this study was to compare the macular and peripapillary capillary vessel density (CVD) and foveal avascular zone (FAZ) in amblyopic eyes of adults with their fellow eyes and with eyes of healthy controls using optical coherence tomography-angiography (OCT-A). METHODS:A total of 34 eyes of 17 patients with anisometropic amblyopia and 80 eyes of 40 age- and gender-matched healthy controls were included. CVD in superficial (SCP) and deep retinal capillary plexuses (DCP), peripapillary region, and FAZ were analyzed by OCT-A. RESULTS:The median ages were 31 years (range 20-64) in patients with amblyopia and 34.5 years (range 24-65) in healthy controls (p = 0.242). The mean FAZ area measured was 0.329 ± 0.024 mm2 in amblyopic eyes, 0.332 ± 0.025 mm2 in fellow eyes, and 0.269 ± 0.015 mm2 in control eyes (p < 0.05). The amblyopic eye of participants showed a decrease in CVD of SCP and DCP (p < 0.001, for all). The inside optic disk CVD measurements were lower in the amblyopic eyes than in the fellow eyes (p = 0.001) and healthy subjects (p = 0.015). CONCLUSION:Significant differences in macular and peripapillary microvasculature were found in anisometropic amblyopic patients. The clinical significance of the results requires further investigation.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Dereli Can Gdoi
10.1007/s10792-020-01345-0subject
Has Abstractpub_date
2020-07-01 00:00:00pages
1765-1772issue
7eissn
0165-5701issn
1573-2630pii
10.1007/s10792-020-01345-0journal_volume
40pub_type
杂志文章abstract:PURPOSE:Regional variations of the preoperative biometry can affect the refractive accuracy of cataract surgery. We aimed to compare the preoperative biometric data for cataract surgery between two domestic institutions. METHODS:We retrospectively reviewed the preoperative biometric data of 673 consecutive eyes underg...
journal_title:International ophthalmology
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pub_type: 临床试验,杂志文章
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