Gentamicin-induced macular infarction in transconjunctival sutureless 25-gauge vitrectomy.

Abstract:

PURPOSE:State Gentamicin antibiotic prophylaxis is contraindicated in 25 gauge Transconjunctival Sutureless Vitrectomy. METHODS:A 75-year-old diabetic woman was affected by glaucoma and mild diabetic retinopathy in both eyes, and epiretinal membrane in the left eye. A 25-gauge Transconjunctival Sutureless Vitrectomy (TSV) was performed with self-sealing transconjunctival scletomies of the left eye. Post-operation antibiotic prophylaxis was obtained by subconconjunctival injection of Gentamicin sulfate (0.4 mg/ml) adjacent to scletomies. RESULTS:A month after the operation visual acuity had not recovered. Fluorescein angiography detected occlusion of perifoveal capillaries. CONCLUSION:Antibiotics, in particular gentamicin, have the potential to cause significant ocular toxicity when they gain access to the inside of the eye, through thinned sclera or sutureless sclerotomies of TSV.

journal_name

Int Ophthalmol

authors

Cardascia N,Boscia F,Furino C,Sborgia L

doi

10.1007/s10792-007-9148-4

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

383-5

issue

5

eissn

0165-5701

issn

1573-2630

journal_volume

28

pub_type

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