Abstract：
PURPOSE:To compare the visual and refractive outcomes between centration on the corneal vertex and the pupil center in corneal refractive surgery. METHODS:A comprehensive literature search was conducted using PubMed, MEDLINE, EMBASE, and the Cochrane Library to identify relevant studies. The primary outcomes were the postoperative spherical equivalent (SE), effectiveness [uncorrected distance visual acuity (UDVA) ≥ 20/20, eyes within ± 0.50 diopter (D) of target refraction], and safety [loss ≥ 2 lines of corrected distance visual acuity (CDVA)]. Higher-order aberrations were considered secondary outcomes. RESULTS:Seven studies describing a total of 1964 eyes were included in this meta-analysis. A statistical significance in postoperative SE was found between the two centration methods for the correction of myopia that favor the CV-centered method (p < 0.001). No significant differences were observed in the proportion of eyes with UDVA ≥ 20/20 or loss ≥ 2 lines of CDVA postoperatively. However, the proportion of eyes within ± 0.50 D was slightly higher (p = 0.02) and the coma aberration was much lower in the corneal vertex-centered method (p < 0.001). CONCLUSION:Preferable visual and refractive outcomes could be achieved with either centering on the corneal vertex or pupil center in corneal refractive surgery; however, the corneal vertex-centered method has shown partial benefits in some clinical indices. In order to obtain higher quality of clinical evidences, more randomized controlled trials (RCTs) are required in further investigations.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Zhang J,Wang Y,Chen X,Wu Wdoi
10.1007/s10792-020-01506-1subject
Has Abstractpub_date
2020-12-01 00:00:00pages
3555-3563issue
12eissn
0165-5701issn
1573-2630pii
10.1007/s10792-020-01506-1journal_volume
40pub_type
杂志文章,评审abstract：:Blindness in diabetics is largely due to retinopathy and/or cataract. Hyperglycaemia and the duration of diabetes are major risk factors for the development of cataract and retinopathy. This review details some of the reactions of glucose that are relevant to the development of complications, and follows the elucidati...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00150976
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journal_title：International ophthalmology
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pub_type： 杂志文章,多中心研究
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更新日期：2014-10-01 00:00:00
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更新日期：2020-04-01 00:00:00
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journal_title：International ophthalmology
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：2017-10-01 00:00:00
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更新日期：2009-02-01 00:00:00
