Abstract：
PURPOSE:To evaluate the long-term safety and efficacy of Mycophenolate Mofetil (MMF) for the control of cystoid macular oedema (CMO) secondary to noninfectious uveitis (NU). METHODS:The medical records of 19 consecutive patients with inflammatory CMO treated with MMF were retrospectively reviewed. Patient demographics, best corrected visual acuity (BCVA), fluorescein angiography (FA), and optical coherence tomography (OCT) findings were evaluated. RESULTS:There were eight females and 11 males with a mean age of 32.9 +/- 8.9 years. After a 1-year follow-up, 18/19 patients (31 eyes, 96.9%, P < 0.05) no longer had signs of CMO, as per their FA and OCT findings; the mean central foveal thickness (CFT) was 167.2 +/- 12.8 microm. At the last follow-up, only 3/19 patients, all affected by Behçet panuveitis, had recurrences of CMO. Mean BCVA improved from 0.34 +/- 0.14 SD at baseline to 0.65 +/- 0.2 SD at last follow-up. CONCLUSIONS:MMF was safe and effective in controlling CMO and in reducing the uveitis relapse rate in patients not responding to traditional immunosuppressants. Further case-controlled studies are mandatory to validate those preliminary results.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Neri P,Mariotti C,Cimino L,Mercanti L,Giovannini Adoi
10.1007/s10792-008-9200-zsubject
Has Abstractpub_date
2009-06-01 00:00:00pages
127-33issue
3eissn
0165-5701issn
1573-2630journal_volume
29pub_type
杂志文章abstract：PURPOSE:To describe the epidemiology and prevalence, rates of progression, difference between adult and pediatric populations, and therapeutic approaches to pediatric keratoconus from documented literature. METHODS:A literature search was done on PubMed using key words including pediatric keratoconus, children with ke...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-017-0699-8
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abstract：:Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus ...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
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更新日期：2008-06-01 00:00:00
abstract：:The beneficial effect of photocoagulation in diabetic retinopathy is now established (2-6, 10). Whereas the capability of providing photocoagulation is widespread, the indications and actual techniques are poorly defined. In this paper, we propose to discuss the principles of photocoagulation. In a following paper the...
journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：1978-09-01 00:00:00
abstract：PURPOSE:Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PE...
journal_title：International ophthalmology
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journal_title：International ophthalmology
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更新日期：1987-08-01 00:00:00
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journal_title：International ophthalmology
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：2007-12-01 00:00:00
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journal_title：International ophthalmology
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更新日期：1996-01-01 00:00:00
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journal_title：International ophthalmology
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：1992-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2011-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-06-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014409829614
更新日期：2001-01-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00224470
更新日期：1991-03-01 00:00:00
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更新日期：1995-01-01 00:00:00
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更新日期：2016-02-01 00:00:00
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更新日期：2018-02-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章,评审
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：1989-01-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：2015-08-01 00:00:00
