Ocular findings in cerebro-ocular-myopathy syndrome (COMS). A possible role of growth factors?

Abstract:

:The clinical and histopathological findings are described in a case of cerebral and ocular abnormalities associated with (congenital) muscular dystrophy. Histopathological examination of the eyes revealed a fetal configuration of the anterior chamber angle, elongated ciliary processes, cataract, persistence of primary hyperplastic vitreous and total retinal detachment with retinal dysplasia. The similarity of ocular findings in Walker-Warburg syndrome, muscle-eye-brain disease and Fukuyama's congenital muscular dystrophy, and the role of growth factors as a possible unifying (foetal) cause are discussed. This case has been presented at the meeting of the EOPS Verhoeff Society, Nürnberg 1991.

journal_name

Int Ophthalmol

authors

Sanders DG,Mooy CM

doi

10.1007/BF01007744

subject

Has Abstract

pub_date

1993-08-01 00:00:00

pages

223-8

issue

4

eissn

0165-5701

issn

1573-2630

journal_volume

17

pub_type

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