Abstract：
OBJECTIVE:To evaluate the efficacy and safety of the bilateral simultaneous XEN (BISIXEN) surgery in open-angle glaucoma patients. METHODS:Retrospective analysis of a prospective data base conducted on uncontrolled glaucoma patients who underwent BISIXEN surgery. Primary endpoint measure was the incidence of sight-threatening complications. Secondary endpoints included intraocular pressure (IOP) reduction and in number of required antiglaucoma medications. RESULTS:Ten patients (20 eyes) were included in the analysis. Median (95% confidence interval) follow-up was 12.0 (7.0-12.0) months, with 14 eyes having a follow-up of 12 months. No sight-threatening complications, such as endophthalmitis, retinal detachment, corneal decompensation, or intraocular hemorrhages were observed in any eye of study sample. Mean IOP decreased significantly from 25.2 (21.5-28.9) mm Hg at baseline to 15.1 (13.4-16.8) mm Hg at the last follow-up visit (p = 0.0001). Mean number of antiglaucoma medications was significantly reduced from 2.9 (2.5 to 3.3) drugs at baseline to 0.40 (0.00-0.70) at the end of the study (p < 0.0001). At the last study visit, 14 (70.0%) eyes had an IOP ≥ 6 and ≤ 18 mm Hg without treatment. Two eyes needed surgical revision and three ones needed a new glaucoma surgery: two underwent Ahmed valves (one eye with aniridia and the other previously operated on) and one underwent non-penetrating deep sclerectomy. CONCLUSIONS:Bilateral simultaneous XEN implantation may be a feasible strategy in those patients with high anesthetic risk.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Urcola A,Garay-Aramburu Gdoi
10.1007/s10792-020-01640-wsubject
Has Abstractpub_date
2021-01-02 00:00:00eissn
0165-5701issn
1573-2630pii
10.1007/s10792-020-01640-wpub_type
杂志文章abstract：:To document the rate of self-reported compliance and glaucoma-related knowledge in Swiss patients and to identify risk factors for their poor compliance. This was an observational study, including a total of 200 consecutive patients already under glaucoma medication in two Swiss tertiary glaucoma clinics (Geneva and B...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-011-9468-2
更新日期：2011-10-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to compare the macular and peripapillary capillary vessel density (CVD) and foveal avascular zone (FAZ) in amblyopic eyes of adults with their fellow eyes and with eyes of healthy controls using optical coherence tomography-angiography (OCT-A). METHODS:A total of 34 eyes of 17 pa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01345-0
更新日期：2020-07-01 00:00:00
abstract：PURPOSE:The study aims to evaluate changes in neopterin levels and tryptophan degradation which are induced by Th1-type immune response and nitric oxide metabolism which may be involved in allergic inflammation. METHODS:Serum nitrite, kynurenine, tryptophan and neopterin levels were evaluated in 36 patients with seaso...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0669-1
更新日期：2018-10-01 00:00:00
abstract：:There has been great controversy about the pathogenesis of the focal changes in the retinal pigment epithelium (RPE) causing detachment of the neurosensory retina in central serous chorioretinopathy (CSC). This study was performed to evaluate changes in choroidal perfusion in 15 patients with CSC. Fluorescein and indo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00133176
更新日期：1995-01-01 00:00:00
abstract：PURPOSE:We aimed to analyze the clinical characteristics of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome. Furthermore, we aimed to correlate the number and location of retinal aneurysms with the size of retinal non-perfusion area and neovascularization. METHODS:Six patients with IRVAN ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0962-7
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:To investigate the changes in ocular higher-order aberrations (HOA) after trabeculectomy using mitomycin-C (MMC). METHODS:We retrospectively reviewed data for 63 eyes from 63 glaucoma patients who had undergone MMC augmented trabeculectomy. We measured intraocular pressure (IOP), refractive errors, anterior ch...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0802-1
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:To provide normal corneal elevation data for a large Caucasian population and to determine the impacts on these data of age, sex, axial length (AXL) and horizontal white-to-white (WW). SETTING:Centro Internacional de Oftalmología Avanzada, Madrid, Spain. DESIGN:Retrospective, cross-sectional, observational. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1028-6
更新日期：2019-09-01 00:00:00
abstract：INTRODUCTION:Uveitis encompasses a wide variety of sight-threatening diseases characterized by intraocular inflammation. It is often classified as infectious and non-infectious uveitis. Unlike infectious uveitis, a distinct infectious agent cannot be identified in non-infectious uveitis and disease origin is usually au...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0984-1
更新日期：2019-07-01 00:00:00
abstract：:Clinical trials are often used to evaluate the efficacy of a given treatment. The results of clinical trials however do not always agree with a clinician's experience or intuition. The merits and demerits of Clinical Trials versus Intuition are discussed by using the laser photocoagulation trials of Proliferative Diab...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00159835
更新日期：1986-05-01 00:00:00
abstract：PURPOSE:To evaluate the long-term safety and efficacy of Mycophenolate Mofetil (MMF) for the control of cystoid macular oedema (CMO) secondary to noninfectious uveitis (NU). METHODS:The medical records of 19 consecutive patients with inflammatory CMO treated with MMF were retrospectively reviewed. Patient demographics...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9200-z
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:To introduce a case of ciliary detachment with primary pulmonary hypertension (PPH). METHODS:The clinical manifestations of a case of ciliary detachment with PPH were addressed by comprehensive examination including ultrasound biological microscope (UBM), intraocular pressure, color fundus photographs, fluores...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0443-4
更新日期：2018-02-01 00:00:00
abstract：:Microtropia is an unilateral strabismus of less than 5 degrees, usually with harmonious anomalous correspondence. Three forms may be distinguished: Primary constant, primary decompensating and consecutive microtropia. In three instances microtropia is important for the ophthalmologist: In assessment of amblyopia appar...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00137371
更新日期：1983-01-01 00:00:00
abstract：:We report the immunopathology and histopathology of a patient with Terson syndrome. The design was an observational case-report. Histopathology and immunohistochemical staining for endoglin (CD105) of an eye from a patient with subarachnoid haemorrhage and Terson syndrome was performed. Immunohistology revealed high p...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9343-6
更新日期：2010-08-01 00:00:00
abstract：:After glaucoma filtering surgery subconjunctival injection of human recombinant tissue plasminogen activator may promote the function of glaucoma filter bleb and increase outflow facility. It can also increase postoperative complications, such as corneal damage. The aim of our research was to determine corneal endothe...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00156413
更新日期：1995-01-01 00:00:00
abstract：:Blindness in diabetics is largely due to retinopathy and/or cataract. Hyperglycaemia and the duration of diabetes are major risk factors for the development of cataract and retinopathy. This review details some of the reactions of glucose that are relevant to the development of complications, and follows the elucidati...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00150976
更新日期：1991-01-01 00:00:00
abstract：:The cone dystrophies can be subdivided into 3 functional stages: central cone disease, peripheral cone disease and diffuse cone disease, respectively. In the patient material of our clinic the sex distribution of patients presenting with te diffuse cone disease stage was abnormal: 22 males and 3 females. The authors s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00155631
更新日期：1987-08-01 00:00:00
abstract：:Ocular wall dimensions (axial eye length, anterior chamber depth, lens thickness, vitreous length, thickness and volume of the ocular wall) were determined by echobiometry on 10 eyes of 10 patients with glaucoma one day before and four days after trabeculectomy. The results showed significant differences: decreased ax...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00917990
更新日期：1992-09-01 00:00:00
abstract：PURPOSE:To report a comparison analysis of accelerated corneal cross-linking (A-CXL) treatment for progressive keratoconus patients in different pediatric age groups. STUDY DESIGN:Retrospective, cross-sectional. METHODS:Patients with progressive keratoconus aged ≤ 18 were retrospectively reviewed. Forty-one eyes of 4...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01446-w
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:To evaluate the accuracy of an advanced manual corneal astigmatic marking method for toric intraocular lens (IOL) implantation. METHODS:From 52 patients, 52 eyes with cataracts and corneal astigmatism were included. The target axis of the toric IOL was marked with the new manual marking method preoperatively a...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01498-y
更新日期：2020-11-01 00:00:00
abstract：:An animal model of keratomycosis was used to study the interaction between the new enzyme antifungal compound mycolase II and the polyene antifungal antibiotic pimaricin. Well established corneal infection caused by an ocular pathogenic candida albicans on New Zealand white male rabbits were treated with 3% mycolase I...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00149150
更新日期：1982-11-01 00:00:00
abstract：:To investigate the efficacy of anti-tuberculous therapy and systemic corticosteroids in patients suffering from active presumed tuberculous choroiditis by the assessment of central retinal sensitivity and fixation characteristics. Six patients (six eyes) with active presumed tuberculous choroiditis were treated with a...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9371-2
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:The quality of cataract surgery delivered in sub-Saharan Africa (SSA) is a significant constraint to achieving the elimination of avoidable blindness. No published reports from routine SSA cataract services attain the WHO benchmarks for visual outcomes; poor outcomes (<6/60) often comprise 20% in published case...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0599-y
更新日期：2018-08-01 00:00:00
abstract：:Traumatic expulsive iridodialysis is a rare complication after trauma by a blunt object in eyes with previous small-incision cataract surgery. The presence of an intact lens capsule with an intraocular lens was thought to protect against damage beyond the posterior capsule. We report a case of dehiscence of the catara...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-011-9491-3
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:This study aims to evaluate the efficacy and safety of XEN45 gel stent (Allergan plc, Dublin, Ireland) in East Asian patients with glaucoma. METHODS:A retrospective study of consecutive XEN45 gel stent implantation surgeries with or without concurrent cataract surgery from May 2017 to August 2018 was performed...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01284-w
更新日期：2020-05-01 00:00:00
abstract：:Lipoid proteinosis is a rare disorder involving multiple organ systems. The ocular manifestations are usually trivial, but greatly aid in the diagnosis. We describe a patient who presented to us with typical moniliform blepharosis. A brief description of relevance to the ophthalmologist and review of the literature fo...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-011-9417-0
更新日期：2011-04-01 00:00:00
abstract：:The aim of this study is to compare a portable spectral domain optical coherence tomography (SD-OCT) device with a non-portable SD-OCT for the identification of anterior chamber angle parameters based on location of Schwalbe's line (SL) and to measure their reproducibility. 99 eyes from 46 normal, healthy participants...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0223-6
更新日期：2017-02-01 00:00:00
abstract：INTRODUCTION:Vogt-Koyanagi-Harada syndrome (VKHS) is an inflammatory systemic autoimmune disease principally affecting pigmented tissues in the ocular, auditory, integumentary and central nervous systems. Patients are generally women in the fourth decade of life. The prognosis is correlated mainly with the time between...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0504-8
更新日期：2018-04-01 00:00:00
abstract：:Diabetes mellitus and pregnancy have reciprocal influences between them, therefore diabetes mellitus may complicate the course of pregnancy as well as pregnancy can worsen the performance of diabetes especially at the fundus oculi. Several factors seem to play a role in retinal neovascularization. Actually it's not po...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9906-z
更新日期：2014-08-01 00:00:00
abstract：PURPOSE:To evaluate the additional intraocular pressure (IOP) lowering effect of gonioscopy-assisted transluminal trabeculotomy (GATT) to contemporary goniosynechialysis (GSL) in endeavouring to abolish subsequent occlusion after chronic iridotrabecular contact in primary angle closure (PAC) patients. METHODS:A retros...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01676-y
更新日期：2021-01-03 00:00:00
abstract：:The purpose of the study was to compare the accuracy of various biometric formulas for predicting postoperative refraction determined using applanation A-scan ultrasound. This retrospective comparative study included 485 eyes that underwent uneventful phacoemulsification with intraocular lens (IOL) implantation. Appla...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0195-6
更新日期：2016-10-01 00:00:00
